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Murcko scaffold

2,4-Diphenylpyridine scaffold

274 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
274
With full pages
24
Scaffold SMILES

c1ccc(-c2ccnc(-c3ccccc3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,4-Diphenylpyridine page
Murcko scaffold c1ccc(-c2ccnc(-c3ccccc3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 274 chemicals

4-[4-(4-Trifluoromethoxyphenyl)-pyridin-2-yl]-benzaldehyde chemical structure, C19H12F3NO2, CAS 1181214-53-8
4-[4-(4-Trifluoromethoxyphenyl)-pyridin-2-yl]-benzaldehyde
CAS 1181214-53-8C19H12F3NO2
2-(3-Nitrophenyl)-4-phenylpyridine chemical structure, C17H12N2O2, CAS 1426022-18-5
2-(3-Nitrophenyl)-4-phenylpyridine
CAS 1426022-18-5C17H12N2O2
2-Phenyl-4-o-tolylpyridine chemical structure, C18H15N, CAS 1215556-61-8
2-Phenyl-4-o-tolylpyridine
CAS 1215556-61-8C18H15N
2-(3-Bromophenyl)-4-phenylpyridine chemical structure, C17H12BrN, CAS 1561960-25-5
2-(3-Bromophenyl)-4-phenylpyridine
CAS 1561960-25-5C17H12BrN
2-(2-Methylphenyl)-4-phenylpyridine chemical structure, C18H15N, CAS 1426022-22-1
2-(2-Methylphenyl)-4-phenylpyridine
CAS 1426022-22-1C18H15N
2-[(3-Cyano-4,6-diphenylpyridin-2-yl)sulfanyl]-N,N-dimethylacetamide chemical structure, C22H19N3OS, CAS 933890-70-1
2-[(3-Cyano-4,6-diphenylpyridin-2-yl)sulfanyl]-N,N-dimethylacetamide
CAS 933890-70-1C22H19N3OS
2-Amino-4-(3-bromophenyl)-6-(4-fluoro-2-(methoxymethoxy)phenyl)nicotinonitrile chemical structure, C20H15BrFN3O2, CAS 925923-84-8
2-Amino-4-(3-bromophenyl)-6-(4-fluoro-2-(methoxymethoxy)phenyl)nicotinonitrile
CAS 925923-84-8C20H15BrFN3O2
3-Methyl-2,4-diphenylpyridine chemical structure, C18H15N, CAS 875228-76-5
3-Methyl-2,4-diphenylpyridine
CAS 875228-76-5C18H15N
4-(4-Isobutylphenyl)-2-phenylpyridine chemical structure, C21H21N, CAS 1414972-03-4
4-(4-Isobutylphenyl)-2-phenylpyridine
CAS 1414972-03-4C21H21N
2-[(2-Cyanoethyl)sulfanyl]-4,6-diphenylpyridine-3-carbonitrile chemical structure, C21H15N3S, CAS 933868-57-6
2-[(2-Cyanoethyl)sulfanyl]-4,6-diphenylpyridine-3-carbonitrile
CAS 933868-57-6C21H15N3S
[(4,6-Diphenylpyridin-2-yl)methyl]propanedinitrile chemical structure, C21H15N3, CAS 89174-44-7
[(4,6-Diphenylpyridin-2-yl)methyl]propanedinitrile
CAS 89174-44-7C21H15N3
[3-(4,6-Diphenylpyridin-2-yl)propyl]propanedinitrile chemical structure, C23H19N3, CAS 89174-47-0
[3-(4,6-Diphenylpyridin-2-yl)propyl]propanedinitrile
CAS 89174-47-0C23H19N3
(4,6-Diphenylpyridin-2-yl)(prop-1-en-1-yl)propanedinitrile chemical structure, C23H17N3, CAS 89174-49-2
(4,6-Diphenylpyridin-2-yl)(prop-1-en-1-yl)propanedinitrile
CAS 89174-49-2C23H17N3
6-(3,4-Dimethylphenyl)-2-methoxy-4-phenylpyridine-3-carbonitrile chemical structure, C21H18N2O, CAS 89572-46-3
6-(3,4-Dimethylphenyl)-2-methoxy-4-phenylpyridine-3-carbonitrile
CAS 89572-46-3C21H18N2O
2-Chloro-6-(3,4-dimethylphenyl)-4-phenylpyridine-3-carbonitrile chemical structure, C20H15ClN2, CAS 89572-51-0
2-Chloro-6-(3,4-dimethylphenyl)-4-phenylpyridine-3-carbonitrile
CAS 89572-51-0C20H15ClN2
6-(3,4-Dimethylphenyl)-2-hydrazinyl-4-phenylpyridine-3-carbonitrile chemical structure, C20H18N4, CAS 89572-54-3
6-(3,4-Dimethylphenyl)-2-hydrazinyl-4-phenylpyridine-3-carbonitrile
CAS 89572-54-3C20H18N4
6-(3,4-Dimethylphenyl)-4-phenylpyridin-2-amine chemical structure, C19H18N2, CAS 89572-63-4
6-(3,4-Dimethylphenyl)-4-phenylpyridin-2-amine
CAS 89572-63-4C19H18N2
2-Methoxy-6-phenyl-4-(3,4,5-trimethoxyphenyl)pyridine-3-carbonitrile chemical structure, C22H20N2O4, CAS 141951-66-8
2-Methoxy-6-phenyl-4-(3,4,5-trimethoxyphenyl)pyridine-3-carbonitrile
CAS 141951-66-8C22H20N2O4
2-Hydrazinyl-4-(4-methoxyphenyl)-6-phenylpyridine-3-carbonitrile chemical structure, C19H16N4O, CAS 833454-58-3
2-Hydrazinyl-4-(4-methoxyphenyl)-6-phenylpyridine-3-carbonitrile
CAS 833454-58-3C19H16N4O
2-Amino-4-(4-aminophenyl)-6-(3-chlorophenyl)pyridine-3-carbonitrile chemical structure, C18H13ClN4, CAS 824933-60-0
2-Amino-4-(4-aminophenyl)-6-(3-chlorophenyl)pyridine-3-carbonitrile
CAS 824933-60-0C18H13ClN4
N-Butyl-3-cyano-4,6-diphenylpyridine-2-carboxamide chemical structure, C23H21N3O, CAS 922522-95-0
N-Butyl-3-cyano-4,6-diphenylpyridine-2-carboxamide
CAS 922522-95-0C23H21N3O
4-(4-Phenylpyridin-2-yl)benzonitrile chemical structure, C18H12N2, CAS 1426022-16-3
4-(4-Phenylpyridin-2-yl)benzonitrile
CAS 1426022-16-3C18H12N2
2-[(3-Cyano-4,6-diphenylpyridin-2-yl)sulfanyl]-N-(2-methylpropyl)acetamide chemical structure, C24H23N3OS, CAS 1440248-92-9
2-[(3-Cyano-4,6-diphenylpyridin-2-yl)sulfanyl]-N-(2-methylpropyl)acetamide
CAS 1440248-92-9C24H23N3OS
2-Chloro-6-(3,4-dimethoxyphenyl)-4-phenylnicotinonitrile chemical structure, C20H15ClN2O2, CAS 1956369-52-0
2-Chloro-6-(3,4-dimethoxyphenyl)-4-phenylnicotinonitrile
CAS 1956369-52-0C20H15ClN2O2