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Murcko scaffold

2,4-Diphenylpyridine scaffold

274 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
274
With full pages
24
Scaffold SMILES

c1ccc(-c2ccnc(-c3ccccc3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,4-Diphenylpyridine page
Murcko scaffold c1ccc(-c2ccnc(-c3ccccc3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 274 chemicals

2-Amino-4-(2,5-dimethylphenyl)-5-ethyl-6-phenylpyridine-3-carbonitrile chemical structure, C22H21N3, CAS 6957-66-0
2-Amino-4-(2,5-dimethylphenyl)-5-ethyl-6-phenylpyridine-3-carbonitrile
CAS 6957-66-0C22H21N3
3-Pyridinecarbonitrile, 2-amino-6-(3-bromophenyl)-4-(4-bromophenyl)- chemical structure, C18H11Br2N3, CAS 642037-10-3
3-Pyridinecarbonitrile, 2-amino-6-(3-bromophenyl)-4-(4-bromophenyl)-
CAS 642037-10-3C18H11Br2N3
2-Amino-4-(3,4-dimethoxyphenyl)-6-(2-nitrophenyl)pyridine-3-carbonitrile chemical structure, C20H16N4O4, CAS 6958-45-8
2-Amino-4-(3,4-dimethoxyphenyl)-6-(2-nitrophenyl)pyridine-3-carbonitrile
CAS 6958-45-8C20H16N4O4
2-Amino-4-(2,6-dichlorophenyl)-6-(2-nitrophenyl)pyridine-3-carbonitrile chemical structure, C18H10Cl2N4O2, CAS 6958-49-2
2-Amino-4-(2,6-dichlorophenyl)-6-(2-nitrophenyl)pyridine-3-carbonitrile
CAS 6958-49-2C18H10Cl2N4O2
2-Amino-4-(3-bromophenyl)-6-(4-cyanophenyl)pyridine-3-carbonitrile chemical structure, C19H11BrN4, CAS 6958-51-6
2-Amino-4-(3-bromophenyl)-6-(4-cyanophenyl)pyridine-3-carbonitrile
CAS 6958-51-6C19H11BrN4
2-Amino-4-(2-methoxyphenyl)-6-(2-methylphenyl)pyridine-3-carbonitrile chemical structure, C20H17N3O, CAS 6958-69-6
2-Amino-4-(2-methoxyphenyl)-6-(2-methylphenyl)pyridine-3-carbonitrile
CAS 6958-69-6C20H17N3O
2-Amino-6-(2-methylphenyl)-4-(2,3,4,5,6-pentafluorophenyl)pyridine-3-carbonitrile chemical structure, C19H10F5N3, CAS 6958-71-0
2-Amino-6-(2-methylphenyl)-4-(2,3,4,5,6-pentafluorophenyl)pyridine-3-carbonitrile
CAS 6958-71-0C19H10F5N3
2,2-Dimethyl-6-[(4,6-diphenyl-2-pyridyl)oxy]hexanoic acid chemical structure, C25H27NO3, CAS 141747-27-5
2,2-Dimethyl-6-[(4,6-diphenyl-2-pyridyl)oxy]hexanoic acid
CAS 141747-27-5C25H27NO3
3-Pyridinecarbonitrile, 2-chloro-4-(4-methylphenyl)-6-phenyl- chemical structure, C19H13ClN2, CAS 143882-76-2
3-Pyridinecarbonitrile, 2-chloro-4-(4-methylphenyl)-6-phenyl-
CAS 143882-76-2C19H13ClN2
6-{[6-(4-Fluorophenyl)-4-phenylpyridin-2-yl]oxy}hexanoic acid chemical structure, C23H22FNO3, CAS 141747-54-8
6-{[6-(4-Fluorophenyl)-4-phenylpyridin-2-yl]oxy}hexanoic acid
CAS 141747-54-8C23H22FNO3
3-Pyridinecarbonitrile, 2-chloro-4-(4-chlorophenyl)-6-phenyl- chemical structure, C18H10Cl2N2, CAS 143882-77-3
3-Pyridinecarbonitrile, 2-chloro-4-(4-chlorophenyl)-6-phenyl-
CAS 143882-77-3C18H10Cl2N2
2-(4-Methylphenyl)-4-phenylpyridine chemical structure, C18H15N, CAS 262362-61-8
2-(4-Methylphenyl)-4-phenylpyridine
CAS 262362-61-8C18H15N
3-Pyridinecarbonitrile, 2-(butylamino)-4,6-diphenyl- chemical structure, C22H21N3, CAS 61006-46-0
3-Pyridinecarbonitrile, 2-(butylamino)-4,6-diphenyl-
CAS 61006-46-0C22H21N3
3-Pyridinecarbonitrile, 2-hydrazino-4,6-diphenyl- chemical structure, C18H14N4, CAS 61006-49-3
3-Pyridinecarbonitrile, 2-hydrazino-4,6-diphenyl-
CAS 61006-49-3C18H14N4
3-Pyridinecarboxamide, 2-methyl-4,6-diphenyl- chemical structure, C19H16N2O, CAS 61448-56-4
3-Pyridinecarboxamide, 2-methyl-4,6-diphenyl-
CAS 61448-56-4C19H16N2O
3,6-Dimethyl-2,4-diphenylpyridine chemical structure, C19H17N, CAS 30342-48-4
3,6-Dimethyl-2,4-diphenylpyridine
CAS 30342-48-4C19H17N
1-(2-Hydroxyethyl)-2-methyl-4,6-diphenylpyridin-1-ium perchlorate chemical structure, C20H20ClNO5, CAS 69821-41-6
1-(2-Hydroxyethyl)-2-methyl-4,6-diphenylpyridin-1-ium perchlorate
CAS 69821-41-6C20H20ClNO5
1-[2-(Acetyloxy)ethyl]-2-methyl-4,6-diphenylpyridin-1-ium perchlorate chemical structure, C22H22ClNO6, CAS 69821-46-1
1-[2-(Acetyloxy)ethyl]-2-methyl-4,6-diphenylpyridin-1-ium perchlorate
CAS 69821-46-1C22H22ClNO6
2-Chloro-6-(4-chlorophenyl)-4-phenylnicotinonitrile chemical structure, C18H10Cl2N2, CAS 69539-06-6
2-Chloro-6-(4-chlorophenyl)-4-phenylnicotinonitrile
CAS 69539-06-6C18H10Cl2N2
Pyridine, 2-(2,2-dimethylpropoxy)-4,6-diphenyl- chemical structure, C22H23NO, CAS 72140-20-6
Pyridine, 2-(2,2-dimethylpropoxy)-4,6-diphenyl-
CAS 72140-20-6C22H23NO
2-Methyl-1-oxo-4,6-diphenyl-1lambda~5~-pyridine chemical structure, C18H15NO, CAS 62094-31-9
2-Methyl-1-oxo-4,6-diphenyl-1lambda~5~-pyridine
CAS 62094-31-9C18H15NO
2-Chloro-4,6-diphenylpyridine chemical structure, C17H12ClN, CAS 76570-24-6
2-Chloro-4,6-diphenylpyridine
CAS 76570-24-6C17H12ClN
4,6-Diphenyl-3-pyridinol chemical structure, C17H13NO, CAS 76570-31-5
4,6-Diphenyl-3-pyridinol
CAS 76570-31-5C17H13NO
1-Methyl-2-(methylsulfanyl)-4,6-diphenylpyridin-1-ium iodide chemical structure, C19H18INS, CAS 83318-99-4
1-Methyl-2-(methylsulfanyl)-4,6-diphenylpyridin-1-ium iodide
CAS 83318-99-4C19H18INS