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Murcko scaffold

3-Phenyl-N-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-propionamide scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
6
With full pages
5
Scaffold SMILES

O=C(CCc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-N-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-propionamide page
Murcko scaffold O=C(CCc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-3-phenylpropanamide chemical structure, C21H22N4O3S, CAS 307545-54-6
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)-3-phenylpropanamide
CAS 307545-54-6C21H22N4O3S
3-Phenyl-N-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-propionamide chemical structure, C19H18N4O3S, CAS 431892-73-8
3-Phenyl-N-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-propionamide
CAS 431892-73-8C19H18N4O3S
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-3-phenylpropanamide chemical structure, C20H20N4O3S, CAS 349431-96-5
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-3-phenylpropanamide
CAS 349431-96-5C20H20N4O3S
3-Phenyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C20H20N4O3S, CAS 521299-90-1
3-Phenyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 521299-90-1C20H20N4O3S
N-[4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl]-3-phenylbutanamide chemical structure, C21H22N4O3S, CAS 432519-78-3
N-[4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl]-3-phenylbutanamide
CAS 432519-78-3C21H22N4O3S
3-(4-Methoxyphenyl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}propanamide chemical structure, C21H22N4O4S, CAS 543693-46-5
3-(4-Methoxyphenyl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}propanamide
CAS 543693-46-5C21H22N4O4S