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Murcko scaffold

Ring system with 3 rings and 19 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
17
With full pages
0
Scaffold SMILES

c1ccc(Nc2ccnc(N3CCOCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ccnc(N3CCOCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

Ethyl 4-((6-methyl-2-morpholinopyrimidin-4-yl)amino)benzoate chemical structure, C18H22N4O3, CAS 380871-99-8
Ethyl 4-((6-methyl-2-morpholinopyrimidin-4-yl)amino)benzoate
CAS 380871-99-8C18H22N4O3
N-(4-Ethoxyphenyl)-6-methyl-2-morpholin-4-ylpyrimidin-4-amine chemical structure, C17H22N4O2, CAS 352224-85-2
N-(4-Ethoxyphenyl)-6-methyl-2-morpholin-4-ylpyrimidin-4-amine
CAS 352224-85-2C17H22N4O2
N-(4-Chlorophenyl)-6-methyl-2-morpholin-4-ylpyrimidin-4-amine chemical structure, C15H17ClN4O, CAS 381699-94-1
N-(4-Chlorophenyl)-6-methyl-2-morpholin-4-ylpyrimidin-4-amine
CAS 381699-94-1C15H17ClN4O
6-Methyl-N-(4-methylphenyl)-2-morpholin-4-ylpyrimidin-4-amine chemical structure, C16H20N4O, CAS 380563-12-2
6-Methyl-N-(4-methylphenyl)-2-morpholin-4-ylpyrimidin-4-amine
CAS 380563-12-2C16H20N4O
N-(4-Fluorophenyl)-6-methyl-2-morpholin-4-yl-5-nitropyrimidin-4-amine chemical structure, C15H16FN5O3, CAS 378212-21-6
N-(4-Fluorophenyl)-6-methyl-2-morpholin-4-yl-5-nitropyrimidin-4-amine
CAS 378212-21-6C15H16FN5O3
N-(4-Ethoxyphenyl)-6-methyl-2-morpholin-4-yl-5-nitropyrimidin-4-amine chemical structure, C17H21N5O4, CAS 378216-29-6
N-(4-Ethoxyphenyl)-6-methyl-2-morpholin-4-yl-5-nitropyrimidin-4-amine
CAS 378216-29-6C17H21N5O4
N-(4-Chlorophenyl)-6-methyl-2-morpholin-4-yl-5-nitropyrimidin-4-amine chemical structure, C15H16ClN5O3, CAS 381171-56-8
N-(4-Chlorophenyl)-6-methyl-2-morpholin-4-yl-5-nitropyrimidin-4-amine
CAS 381171-56-8C15H16ClN5O3
N-(4-Methoxyphenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine chemical structure, C16H19N5O4, CAS 378208-76-5
N-(4-Methoxyphenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine
CAS 378208-76-5C16H19N5O4
2-(2,6-Dimethylmorpholino)-N4-(2-fluorophenyl)-5-nitropyrimidine-4,6-diamine chemical structure, C16H19FN6O3, CAS 835907-14-7
2-(2,6-Dimethylmorpholino)-N4-(2-fluorophenyl)-5-nitropyrimidine-4,6-diamine
CAS 835907-14-7C16H19FN6O3
N4-(2,5-dimethoxyphenyl)-2-morpholino-5-nitropyrimidine-4,6-diamine chemical structure, C16H20N6O5, CAS 674363-26-9
N4-(2,5-dimethoxyphenyl)-2-morpholino-5-nitropyrimidine-4,6-diamine
CAS 674363-26-9C16H20N6O5
2-(2,6-Dimethylmorpholino)-N4-(4-ethoxyphenyl)-5-nitropyrimidine-4,6-diamine chemical structure, C18H24N6O4, CAS 674305-82-9
2-(2,6-Dimethylmorpholino)-N4-(4-ethoxyphenyl)-5-nitropyrimidine-4,6-diamine
CAS 674305-82-9C18H24N6O4
N4-(2-methoxyphenyl)-2-morpholino-5-nitropyrimidine-4,6-diamine chemical structure, C15H18N6O4, CAS 672944-29-5
N4-(2-methoxyphenyl)-2-morpholino-5-nitropyrimidine-4,6-diamine
CAS 672944-29-5C15H18N6O4
2-(2,6-Dimethylmorpholin-4-yl)-N-(3-fluorophenyl)-5-nitropyrimidine-4,6-diamine chemical structure, C16H19FN6O3, CAS 585551-83-3
2-(2,6-Dimethylmorpholin-4-yl)-N-(3-fluorophenyl)-5-nitropyrimidine-4,6-diamine
CAS 585551-83-3C16H19FN6O3
2-(2,6-Dimethylmorpholin-4-yl)-N-(4-fluorophenyl)-6-methyl-5-nitropyrimidin-4-amine chemical structure, C17H20FN5O3, CAS 1203055-43-9
2-(2,6-Dimethylmorpholin-4-yl)-N-(4-fluorophenyl)-6-methyl-5-nitropyrimidin-4-amine
CAS 1203055-43-9C17H20FN5O3
N-[2-[(6-Chloro-2-morpholin-4-yl-pyrimidin-4-yl)amino]phenyl]-2,2,2-trifluoro-acetamide chemical structure, C16H15ClF3N5O2, CAS 1013402-34-0
N-[2-[(6-Chloro-2-morpholin-4-yl-pyrimidin-4-yl)amino]phenyl]-2,2,2-trifluoro-acetamide
CAS 1013402-34-0C16H15ClF3N5O2
N1-(6-Methyl-2-morpholinopyrimidin-4-yl)benzene-1,4-diamine chemical structure, C15H19N5O, CAS 1706442-79-6
N1-(6-Methyl-2-morpholinopyrimidin-4-yl)benzene-1,4-diamine
CAS 1706442-79-6C15H19N5O
6-Chloro-N-(4-chlorophenyl)-2-morpholinopyrimidin-4-amine chemical structure, C14H14Cl2N4O, CAS 1902975-81-8
6-Chloro-N-(4-chlorophenyl)-2-morpholinopyrimidin-4-amine
CAS 1902975-81-8C14H14Cl2N4O