CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
14
With full pages
3
Scaffold SMILES

O=c1c(NC(=S)Nc2ccccc2)c[nH]n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(NC(=S)Nc2ccccc2)c[nH]n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

3-(4-Antipyrinyl)-1-phenyl-2-thiourea chemical structure, C18H18N4OS, CAS 51641-29-3
3-(4-Antipyrinyl)-1-phenyl-2-thiourea
CAS 51641-29-3C18H18N4OS
4-((((4-Chlorophenyl)amino)thioxomethyl)amino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one chemical structure, C18H17ClN4OS, CAS 51944-21-9
4-((((4-Chlorophenyl)amino)thioxomethyl)amino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
CAS 51944-21-9C18H17ClN4OS
Ethyl 4-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)carbamothioylamino]benzoate chemical structure, C21H22N4O3S, CAS 380344-22-9
Ethyl 4-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)carbamothioylamino]benzoate
CAS 380344-22-9C21H22N4O3S
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-methylphenyl)thiourea chemical structure, C19H20N4OS, CAS 51944-22-0
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-methylphenyl)thiourea
CAS 51944-22-0C19H20N4OS
1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(3-hydroxyphenyl)thiourea chemical structure, C18H18N4O2S, CAS 402945-04-4
1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(3-hydroxyphenyl)thiourea
CAS 402945-04-4C18H18N4O2S
Urea, 3-(4-antipyrinyl)-1-(p-ethoxyphenyl)-2-thio- chemical structure, C20H22N4O2S, CAS 74051-62-0
Urea, 3-(4-antipyrinyl)-1-(p-ethoxyphenyl)-2-thio-
CAS 74051-62-0C20H22N4O2S
1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(3-methoxyphenyl)thiourea chemical structure, C19H20N4O2S, CAS 337470-05-0
1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(3-methoxyphenyl)thiourea
CAS 337470-05-0C19H20N4O2S
(Z)-N'-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-(4-((perfluoropropyl)thio)phenyl)carbamimidothioic acid chemical structure, C21H17F7N4OS2, CAS 304475-00-1
(Z)-N'-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-(4-((perfluoropropyl)thio)phenyl)carbamimidothioic acid
CAS 304475-00-1C21H17F7N4OS2
1-(4-Butylphenyl)-3-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)thiourea chemical structure, C22H26N4OS, CAS 436126-95-3
1-(4-Butylphenyl)-3-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)thiourea
CAS 436126-95-3C22H26N4OS
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-nitrophenyl)thiourea chemical structure, C18H17N5O3S, CAS 101721-59-9
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-nitrophenyl)thiourea
CAS 101721-59-9C18H17N5O3S
4-((((4-Methoxyphenyl)amino)thioxomethyl)amino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one chemical structure, C19H20N4O2S, CAS 74051-63-1
4-((((4-Methoxyphenyl)amino)thioxomethyl)amino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
CAS 74051-63-1C19H20N4O2S
Urea, 3-(4-antipyrinyl)-1-(p-(1-methylbutoxy)phenyl)-2-thio- chemical structure, C23H28N4O2S, CAS 73953-54-5
Urea, 3-(4-antipyrinyl)-1-(p-(1-methylbutoxy)phenyl)-2-thio-
CAS 73953-54-5C23H28N4O2S
Urea, 3-(4-antipyrinyl)-1-(p-pentoxyphenyl)-2-thio- chemical structure, C23H28N4O2S, CAS 73953-58-9
Urea, 3-(4-antipyrinyl)-1-(p-pentoxyphenyl)-2-thio-
CAS 73953-58-9C23H28N4O2S
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-isopropylphenyl)thiourea chemical structure, C21H24N4OS, CAS 682788-47-2
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-isopropylphenyl)thiourea
CAS 682788-47-2C21H24N4OS