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Murcko scaffold

6-Phenyl-2-pyridone scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
360
With full pages
43
Scaffold SMILES

O=c1cccc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-2-pyridone page
Murcko scaffold O=c1cccc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 360 chemicals

6-(3-Chloro-2-methylphenyl)-2-hydroxypyridine chemical structure, C12H10ClNO, CAS 1111111-61-5
6-(3-Chloro-2-methylphenyl)-2-hydroxypyridine
CAS 1111111-61-5C12H10ClNO
6-(3-Chloro-4-methylphenyl)-2-hydroxypyridine chemical structure, C12H10ClNO, CAS 1111111-03-5
6-(3-Chloro-4-methylphenyl)-2-hydroxypyridine
CAS 1111111-03-5C12H10ClNO
6-(3-Chloro-5-methylphenyl)-2-hydroxypyridine chemical structure, C12H10ClNO, CAS 1261981-70-7
6-(3-Chloro-5-methylphenyl)-2-hydroxypyridine
CAS 1261981-70-7C12H10ClNO
6-(4-Chloro-2-methylphenyl)-2-hydroxypyridine chemical structure, C12H10ClNO, CAS 1111111-30-8
6-(4-Chloro-2-methylphenyl)-2-hydroxypyridine
CAS 1111111-30-8C12H10ClNO
6-(4-Chloro-3-methylphenyl)-2-hydroxypyridine chemical structure, C12H10ClNO, CAS 1111110-95-2
6-(4-Chloro-3-methylphenyl)-2-hydroxypyridine
CAS 1111110-95-2C12H10ClNO
6-(2-Chloro-5-hydroxyphenyl)pyridin-2(1H)-one chemical structure, C11H8ClNO2, CAS 1261993-05-8
6-(2-Chloro-5-hydroxyphenyl)pyridin-2(1H)-one
CAS 1261993-05-8C11H8ClNO2
6-(3-Chloro-5-fluorophenyl)pyridin-2(1H)-one chemical structure, C11H7ClFNO, CAS 1111111-69-3
6-(3-Chloro-5-fluorophenyl)pyridin-2(1H)-one
CAS 1111111-69-3C11H7ClFNO
6-(3-Chloro-4-fluorophenyl)pyridin-2(1H)-one chemical structure, C11H7ClFNO, CAS 1111110-75-8
6-(3-Chloro-4-fluorophenyl)pyridin-2(1H)-one
CAS 1111110-75-8C11H7ClFNO
6-(2,4,6-Trifluorophenyl)pyridin-2(1H)-one chemical structure, C11H6F3NO, CAS 1111111-16-0
6-(2,4,6-Trifluorophenyl)pyridin-2(1H)-one
CAS 1111111-16-0C11H6F3NO
6-(3-Acetylaminophenyl)-2-hydroxypyridine chemical structure, C13H12N2O2, CAS 1111114-89-6
6-(3-Acetylaminophenyl)-2-hydroxypyridine
CAS 1111114-89-6C13H12N2O2
2-Hydroxy-6-[3-(N-methylaminocarbonyl)phenyl]pyridine chemical structure, C13H12N2O2, CAS 1261908-75-1
2-Hydroxy-6-[3-(N-methylaminocarbonyl)phenyl]pyridine
CAS 1261908-75-1C13H12N2O2
2-Hydroxy-6-(3-methoxycarbonylphenyl)pyridine chemical structure, C13H11NO3, CAS 1111105-60-2
2-Hydroxy-6-(3-methoxycarbonylphenyl)pyridine
CAS 1111105-60-2C13H11NO3
2-Hydroxy-6-(4-methoxycarbonylphenyl)pyridine chemical structure, C13H11NO3, CAS 1111105-59-9
2-Hydroxy-6-(4-methoxycarbonylphenyl)pyridine
CAS 1111105-59-9C13H11NO3
6-(4-Ethoxy-2-methylphenyl)-2-hydroxypyridine chemical structure, C14H15NO2, CAS 1111111-62-6
6-(4-Ethoxy-2-methylphenyl)-2-hydroxypyridine
CAS 1111111-62-6C14H15NO2
6-(4-Chloro-3-cyanophenyl)-2-hydroxypyridine chemical structure, C12H7ClN2O, CAS 1261993-28-5
6-(4-Chloro-3-cyanophenyl)-2-hydroxypyridine
CAS 1261993-28-5C12H7ClN2O
6-(2,4-Dimethoxyphenyl)-2-hydroxypyridine chemical structure, C13H13NO3, CAS 1111110-57-6
6-(2,4-Dimethoxyphenyl)-2-hydroxypyridine
CAS 1111110-57-6C13H13NO3
6-(2,5-Dimethoxyphenyl)-2-hydroxypyridine chemical structure, C13H13NO3, CAS 30831-49-3
6-(2,5-Dimethoxyphenyl)-2-hydroxypyridine
CAS 30831-49-3C13H13NO3
6-(3,4-Dimethoxyphenyl)pyridin-2(1H)-one chemical structure, C13H13NO3, CAS 34672-75-8
6-(3,4-Dimethoxyphenyl)pyridin-2(1H)-one
CAS 34672-75-8C13H13NO3
6-(3,5-Dimethoxyphenyl)-2-hydroxypyridine chemical structure, C13H13NO3, CAS 1111111-23-9
6-(3,5-Dimethoxyphenyl)-2-hydroxypyridine
CAS 1111111-23-9C13H13NO3
6-(4-Ethylthiophenyl)-2-hydroxypyridine chemical structure, C13H13NOS, CAS 1261915-59-6
6-(4-Ethylthiophenyl)-2-hydroxypyridine
CAS 1261915-59-6C13H13NOS
6-(3-Carboxy-5-fluorophenyl)-2-hydroxypyridine chemical structure, C12H8FNO3, CAS 1261915-74-5
6-(3-Carboxy-5-fluorophenyl)-2-hydroxypyridine
CAS 1261915-74-5C12H8FNO3
6-(4-Carboxy-3-fluorophenyl)-2-hydroxypyridine chemical structure, C12H8FNO3, CAS 1111110-44-1
6-(4-Carboxy-3-fluorophenyl)-2-hydroxypyridine
CAS 1111110-44-1C12H8FNO3
6-(5-Carboxy-2-fluorophenyl)-2-hydroxypyridine chemical structure, C12H8FNO3, CAS 1261972-78-4
6-(5-Carboxy-2-fluorophenyl)-2-hydroxypyridine
CAS 1261972-78-4C12H8FNO3
6-(2-Chloro-5-methoxyphenyl)-2-hydroxypyridine chemical structure, C12H10ClNO2, CAS 1111105-46-4
6-(2-Chloro-5-methoxyphenyl)-2-hydroxypyridine
CAS 1111105-46-4C12H10ClNO2