CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 13 atoms

71 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
71
With full pages
16
Scaffold SMILES

O=C(Nc1cccs1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccs1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 71 of 71 chemicals

2,4-Dimethyl 3-(bromomethyl)-5-(thiophene-2-amido)thiophene-2,4-dicarboxylate chemical structure, C14H12BrNO5S2, CAS 871673-28-8
2,4-Dimethyl 3-(bromomethyl)-5-(thiophene-2-amido)thiophene-2,4-dicarboxylate
CAS 871673-28-8C14H12BrNO5S2
Ethyl 2-(5-nitrothiophene-2-carboxamido)thiophene-3-carboxylate chemical structure, C12H10N2O5S2, CAS 896680-42-5
Ethyl 2-(5-nitrothiophene-2-carboxamido)thiophene-3-carboxylate
CAS 896680-42-5C12H10N2O5S2
Ethyl 2-(5-bromothiophene-2-carboxamido)thiophene-3-carboxylate chemical structure, C12H10BrNO3S2, CAS 896680-45-8
Ethyl 2-(5-bromothiophene-2-carboxamido)thiophene-3-carboxylate
CAS 896680-45-8C12H10BrNO3S2
Methyl 2-(5-nitrothiophene-2-carboxamido)thiophene-3-carboxylate chemical structure, C11H8N2O5S2, CAS 921054-21-9
Methyl 2-(5-nitrothiophene-2-carboxamido)thiophene-3-carboxylate
CAS 921054-21-9C11H8N2O5S2
Ethyl 2-(5-chlorothiophene-2-carboxamido)thiophene-3-carboxylate chemical structure, C12H10ClNO3S2, CAS 899350-94-8
Ethyl 2-(5-chlorothiophene-2-carboxamido)thiophene-3-carboxylate
CAS 899350-94-8C12H10ClNO3S2
N-(3-Carbamoylthiophen-2-yl)-5-chlorothiophene-2-carboxamide chemical structure, C10H7ClN2O2S2, CAS 864941-20-8
N-(3-Carbamoylthiophen-2-yl)-5-chlorothiophene-2-carboxamide
CAS 864941-20-8C10H7ClN2O2S2
2-(5-Bromothiophene-2-amido)-N-methylthiophene-3-carboxamide chemical structure, C11H9BrN2O2S2, CAS 888413-29-4
2-(5-Bromothiophene-2-amido)-N-methylthiophene-3-carboxamide
CAS 888413-29-4C11H9BrN2O2S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-5-nitrothiophene-2-carboxamide chemical structure, C12H9N3O3S2, CAS 896301-85-2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-5-nitrothiophene-2-carboxamide
CAS 896301-85-2C12H9N3O3S2
N,4,5-trimethyl-2-[(5-nitrothiophene-2-carbonyl)amino]thiophene-3-carboxamide chemical structure, C13H13N3O4S2, CAS 896294-39-6
N,4,5-trimethyl-2-[(5-nitrothiophene-2-carbonyl)amino]thiophene-3-carboxamide
CAS 896294-39-6C13H13N3O4S2
5-Chloro-N-(4,5-dimethyl-3-(methylcarbamoyl)thiophen-2-yl)thiophene-2-carboxamide chemical structure, C13H13ClN2O2S2, CAS 896302-05-9
5-Chloro-N-(4,5-dimethyl-3-(methylcarbamoyl)thiophen-2-yl)thiophene-2-carboxamide
CAS 896302-05-9C13H13ClN2O2S2
4,5-Dimethyl-2-[(5-nitrothiophene-2-carbonyl)amino]thiophene-3-carboxamide chemical structure, C12H11N3O4S2, CAS 896307-64-5
4,5-Dimethyl-2-[(5-nitrothiophene-2-carbonyl)amino]thiophene-3-carboxamide
CAS 896307-64-5C12H11N3O4S2
N,4,5-trimethyl-2-(thiophene-2-carbonylamino)thiophene-3-carboxamide chemical structure, C13H14N2O2S2, CAS 896293-46-2
N,4,5-trimethyl-2-(thiophene-2-carbonylamino)thiophene-3-carboxamide
CAS 896293-46-2C13H14N2O2S2
5-Bromo-N-(4,5-dimethyl-3-(methylcarbamoyl)thiophen-2-yl)thiophene-2-carboxamide chemical structure, C13H13BrN2O2S2, CAS 896294-81-8
5-Bromo-N-(4,5-dimethyl-3-(methylcarbamoyl)thiophen-2-yl)thiophene-2-carboxamide
CAS 896294-81-8C13H13BrN2O2S2
Methyl (4,5-dimethyl-2-(thiophene-2-carboxamido)thiophene-3-carbonyl)carbamate chemical structure, C14H14N2O4S2, CAS 896304-21-5
Methyl (4,5-dimethyl-2-(thiophene-2-carboxamido)thiophene-3-carbonyl)carbamate
CAS 896304-21-5C14H14N2O4S2
Ethyl 4-cyano-3-methyl-5-(5-nitrothiophene-2-carboxamido)thiophene-2-carboxylate chemical structure, C14H11N3O5S2, CAS 896321-60-1
Ethyl 4-cyano-3-methyl-5-(5-nitrothiophene-2-carboxamido)thiophene-2-carboxylate
CAS 896321-60-1C14H11N3O5S2
Ethyl 5-(5-chlorothiophene-2-carboxamido)-4-cyano-3-methylthiophene-2-carboxylate chemical structure, C14H11ClN2O3S2, CAS 896325-37-4
Ethyl 5-(5-chlorothiophene-2-carboxamido)-4-cyano-3-methylthiophene-2-carboxylate
CAS 896325-37-4C14H11ClN2O3S2
Ethyl 3-methyl-4-thiocyanato-5-(thiophene-2-carboxamido)thiophene-2-carboxylate chemical structure, C14H12N2O3S3, CAS 681157-90-4
Ethyl 3-methyl-4-thiocyanato-5-(thiophene-2-carboxamido)thiophene-2-carboxylate
CAS 681157-90-4C14H12N2O3S3
2-(Thiophene-2-amido)thiophene-3-carboxylic acid chemical structure, C10H7NO3S2, CAS 926235-66-7
2-(Thiophene-2-amido)thiophene-3-carboxylic acid
CAS 926235-66-7C10H7NO3S2
Methyl 5-(5-chlorothiophene-2-carboxamido)-4-cyano-3-methylthiophene-2-carboxylate chemical structure, C13H9ClN2O3S2, CAS 922860-02-4
Methyl 5-(5-chlorothiophene-2-carboxamido)-4-cyano-3-methylthiophene-2-carboxylate
CAS 922860-02-4C13H9ClN2O3S2
Methyl 2-{[(4-bromo-5-propylthiophen-2-yl)carbonyl]amino}-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate chemical structure, C20H25BrN2O4S2, CAS 669734-42-3
Methyl 2-{[(4-bromo-5-propylthiophen-2-yl)carbonyl]amino}-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate
CAS 669734-42-3C20H25BrN2O4S2
Methyl (2-(5-bromothiophene-2-carboxamido)-4,5-dimethylthiophene-3-carbonyl)carbamate chemical structure, C14H13BrN2O4S2, CAS 896305-49-0
Methyl (2-(5-bromothiophene-2-carboxamido)-4,5-dimethylthiophene-3-carbonyl)carbamate
CAS 896305-49-0C14H13BrN2O4S2
Ethyl 2-(5-bromothiophene-2-carboxamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C14H14BrNO3S2, CAS 477546-12-6
Ethyl 2-(5-bromothiophene-2-carboxamido)-4,5-dimethylthiophene-3-carboxylate
CAS 477546-12-6C14H14BrNO3S2
2,4-Dimethyl 3-(bromomethyl)-5-(5-bromothiophene-2-amido)thiophene-2,4-dicarboxylate chemical structure, C14H11Br2NO5S2, CAS 1803583-73-4
2,4-Dimethyl 3-(bromomethyl)-5-(5-bromothiophene-2-amido)thiophene-2,4-dicarboxylate
CAS 1803583-73-4C14H11Br2NO5S2