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Murcko scaffold

3-Pyridinecarboxamide, N-(4-phenyl-2-thiazolyl)- scaffold

80 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
80
With full pages
9
Scaffold SMILES

O=C(Nc1nc(-c2ccccc2)cs1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Pyridinecarboxamide, N-(4-phenyl-2-thiazolyl)- page
Murcko scaffold O=C(Nc1nc(-c2ccccc2)cs1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 80 chemicals

3-Pyridinecarboxamide, N-(4-phenyl-2-thiazolyl)- chemical structure, C15H11N3OS, CAS 14397-15-0
3-Pyridinecarboxamide, N-(4-phenyl-2-thiazolyl)-
CAS 14397-15-0C15H11N3OS
3-Pyridinecarboxamide, N-(4-(4-chlorophenyl)-2-thiazolyl)- chemical structure, C15H10ClN3OS, CAS 66063-69-2
3-Pyridinecarboxamide, N-(4-(4-chlorophenyl)-2-thiazolyl)-
CAS 66063-69-2C15H10ClN3OS
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H10FN3OS, CAS 326914-70-9
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 326914-70-9C15H10FN3OS
N-[4-(4-Ethoxyphenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C17H15N3O2S, CAS 329227-32-9
N-[4-(4-Ethoxyphenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 329227-32-9C17H15N3O2S
N-[4-(2,4-Dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C18H17N3OS, CAS 459792-85-9
N-[4-(2,4-Dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 459792-85-9C18H17N3OS
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)nicotinamide chemical structure, C16H13N3OS, CAS 333433-07-1
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)nicotinamide
CAS 333433-07-1C16H13N3OS
N-[4-(2,4-Difluorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H9F2N3OS, CAS 545385-53-3
N-[4-(2,4-Difluorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 545385-53-3C15H9F2N3OS
N-(4-(4-Bromophenyl)thiazol-2-yl)nicotinamide chemical structure, C15H10BrN3OS, CAS 309293-36-5
N-(4-(4-Bromophenyl)thiazol-2-yl)nicotinamide
CAS 309293-36-5C15H10BrN3OS
5-Bromo-N-[(2Z)-4-(4-methylphenyl)-1,3-thiazol-2(3H)-ylidene]pyridine-3-carboxamide chemical structure, C16H12BrN3OS, CAS 307545-59-1
5-Bromo-N-[(2Z)-4-(4-methylphenyl)-1,3-thiazol-2(3H)-ylidene]pyridine-3-carboxamide
CAS 307545-59-1C16H12BrN3OS
5-Bromo-N-(5-methyl-4-p-tolyl-thiazol-2-yl)-nicotinamide chemical structure, C17H14BrN3OS, CAS 329226-82-6
5-Bromo-N-(5-methyl-4-p-tolyl-thiazol-2-yl)-nicotinamide
CAS 329226-82-6C17H14BrN3OS
5-Bromo-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H9BrClN3OS, CAS 429642-20-6
5-Bromo-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 429642-20-6C15H9BrClN3OS
5-Bromo-N-(4-phenyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C15H10BrN3OS, CAS 329224-42-2
5-Bromo-N-(4-phenyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 329224-42-2C15H10BrN3OS
5-Bromo-N-[(2E)-4-(4-ethoxyphenyl)-1,3-thiazol-2(3H)-ylidene]pyridine-3-carboxamide chemical structure, C17H14BrN3O2S, CAS 329227-36-3
5-Bromo-N-[(2E)-4-(4-ethoxyphenyl)-1,3-thiazol-2(3H)-ylidene]pyridine-3-carboxamide
CAS 329227-36-3C17H14BrN3O2S
2-Chloro-N-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H9ClN4O3S, CAS 313386-76-4
2-Chloro-N-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 313386-76-4C15H9ClN4O3S
2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H8Cl3N3OS, CAS 352678-64-9
2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 352678-64-9C15H8Cl3N3OS
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C17H15N3OS, CAS 717869-26-6
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 717869-26-6C17H15N3OS
N-[4-(3-Bromo-4-methoxyphenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C16H12BrN3O2S, CAS 330178-01-3
N-[4-(3-Bromo-4-methoxyphenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 330178-01-3C16H12BrN3O2S
N-[4-(4-Bromophenyl)-5-methyl-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C16H12BrN3OS, CAS 416873-39-7
N-[4-(4-Bromophenyl)-5-methyl-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 416873-39-7C16H12BrN3OS
N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H9Cl2N3OS, CAS 420090-03-5
N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 420090-03-5C15H9Cl2N3OS
5-Bromo-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide chemical structure, C15H9BrClN3OS, CAS 773863-52-8
5-Bromo-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
CAS 773863-52-8C15H9BrClN3OS
N-(4-Mesitylthiazol-2-yl)-2-(methylthio)nicotinamide chemical structure, C19H19N3OS2, CAS 771511-45-6
N-(4-Mesitylthiazol-2-yl)-2-(methylthio)nicotinamide
CAS 771511-45-6C19H19N3OS2
N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide chemical structure, C16H11F2N3OS2, CAS 784159-79-1
N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide
CAS 784159-79-1C16H11F2N3OS2
N-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-2-(methylthio)nicotinamide chemical structure, C18H17N3O3S2, CAS 784160-43-6
N-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-2-(methylthio)nicotinamide
CAS 784160-43-6C18H17N3O3S2
N-(4-(2,5-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide chemical structure, C16H11F2N3OS2, CAS 784162-36-3
N-(4-(2,5-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide
CAS 784162-36-3C16H11F2N3OS2