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Murcko scaffold

Ring system with 3 rings and 20 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
18
With full pages
0
Scaffold SMILES

O=C(N1CCCCC1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(N1CCCCC1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

4-(2,3-Dimethylphenyl)piperazinyl piperidyl ketone chemical structure, C18H27N3O, CAS 501104-54-7
4-(2,3-Dimethylphenyl)piperazinyl piperidyl ketone
CAS 501104-54-7C18H27N3O
4-(2,6-Dimethylphenyl)piperazinyl piperidyl ketone chemical structure, C18H27N3O, CAS 713097-29-1
4-(2,6-Dimethylphenyl)piperazinyl piperidyl ketone
CAS 713097-29-1C18H27N3O
1-(4-Chlorophenyl)-4-(piperidine-1-carbonyl)piperazine chemical structure, C16H22ClN3O, CAS 701222-61-9
1-(4-Chlorophenyl)-4-(piperidine-1-carbonyl)piperazine
CAS 701222-61-9C16H22ClN3O
1-(2,5-Dichlorophenyl)-4-(piperidine-1-carbonyl)piperazine chemical structure, C16H21Cl2N3O, CAS 501104-57-0
1-(2,5-Dichlorophenyl)-4-(piperidine-1-carbonyl)piperazine
CAS 501104-57-0C16H21Cl2N3O
(4-(3-Chloro-4-methylphenyl)piperazin-1-yl)(piperidin-1-yl)methanone chemical structure, C17H24ClN3O, CAS 501104-28-5
(4-(3-Chloro-4-methylphenyl)piperazin-1-yl)(piperidin-1-yl)methanone
CAS 501104-28-5C17H24ClN3O
1-(3,4-Dimethylphenyl)-4-(piperidine-1-carbonyl)piperazine chemical structure, C18H27N3O, CAS 501104-34-3
1-(3,4-Dimethylphenyl)-4-(piperidine-1-carbonyl)piperazine
CAS 501104-34-3C18H27N3O
(4-(3,4-Dichlorophenyl)piperazin-1-yl)(piperidin-1-yl)methanone chemical structure, C16H21Cl2N3O, CAS 501104-40-1
(4-(3,4-Dichlorophenyl)piperazin-1-yl)(piperidin-1-yl)methanone
CAS 501104-40-1C16H21Cl2N3O
(4-(2-Fluorophenyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C17H24FN3O, CAS 890605-08-0
(4-(2-Fluorophenyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone
CAS 890605-08-0C17H24FN3O
(4-(4-Methoxyphenyl)piperazin-1-yl)(piperidin-1-yl)methanone chemical structure, C17H25N3O2, CAS 927640-66-2
(4-(4-Methoxyphenyl)piperazin-1-yl)(piperidin-1-yl)methanone
CAS 927640-66-2C17H25N3O2
(4-(4-Methoxyphenyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C18H27N3O2, CAS 927640-68-4
(4-(4-Methoxyphenyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone
CAS 927640-68-4C18H27N3O2
(4-(2,3-Dimethylphenyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone chemical structure, C19H29N3O, CAS 890605-14-8
(4-(2,3-Dimethylphenyl)piperazin-1-yl)(4-methylpiperidin-1-yl)methanone
CAS 890605-14-8C19H29N3O
4-(4-Fluorophenyl)piperazinyl 4-methylpiperidyl ketone chemical structure, C17H24FN3O, CAS 890605-02-4
4-(4-Fluorophenyl)piperazinyl 4-methylpiperidyl ketone
CAS 890605-02-4C17H24FN3O
1-(4-Chlorophenyl)-4-[(4-methyl-1-piperidinyl)carbonyl]piperazine chemical structure, C17H24ClN3O, CAS 890601-29-3
1-(4-Chlorophenyl)-4-[(4-methyl-1-piperidinyl)carbonyl]piperazine
CAS 890601-29-3C17H24ClN3O
4-(2,5-Dichlorophenyl)piperazinyl 4-methylpiperidyl ketone chemical structure, C17H23Cl2N3O, CAS 890601-25-9
4-(2,5-Dichlorophenyl)piperazinyl 4-methylpiperidyl ketone
CAS 890601-25-9C17H23Cl2N3O
4-(2-Chlorophenyl)piperazinyl 4-methylpiperidyl ketone chemical structure, C17H24ClN3O, CAS 890605-38-6
4-(2-Chlorophenyl)piperazinyl 4-methylpiperidyl ketone
CAS 890605-38-6C17H24ClN3O
4-(3-Chlorophenyl)piperazinyl 4-methylpiperidyl ketone chemical structure, C17H24ClN3O, CAS 890605-32-0
4-(3-Chlorophenyl)piperazinyl 4-methylpiperidyl ketone
CAS 890605-32-0C17H24ClN3O
4-(5-Chloro-2-methylphenyl)piperazinyl 4-methylpiperidyl ketone chemical structure, C18H26ClN3O, CAS 890605-26-2
4-(5-Chloro-2-methylphenyl)piperazinyl 4-methylpiperidyl ketone
CAS 890605-26-2C18H26ClN3O
1-(3-Chloro-2-methylphenyl)-4-[(4-methyl-1-piperidinyl)carbonyl]piperazine chemical structure, C18H26ClN3O, CAS 890605-20-6
1-(3-Chloro-2-methylphenyl)-4-[(4-methyl-1-piperidinyl)carbonyl]piperazine
CAS 890605-20-6C18H26ClN3O