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Murcko scaffold

1-Benzoyl-4-phenylpiperazine scaffold

844 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
844
With full pages
177
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzoyl-4-phenylpiperazine page
Murcko scaffold O=C(c1ccccc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 844 chemicals

Ketone, 4-phenylpiperazinyl 3,4,5-trimethoxyphenyl chemical structure, C20H24N2O4, CAS 17766-63-1
Ketone, 4-phenylpiperazinyl 3,4,5-trimethoxyphenyl
CAS 17766-63-1C20H24N2O4
Ketone, 4-(p-chlorophenyl)piperazinyl 3,4,5-trimethoxyphenyl chemical structure, C20H23ClN2O4, CAS 17766-66-4
Ketone, 4-(p-chlorophenyl)piperazinyl 3,4,5-trimethoxyphenyl
CAS 17766-66-4C20H23ClN2O4
(4-(2-Methoxyphenyl)-1-piperazinyl)(3,4,5-trimethoxyphenyl)methanone chemical structure, C21H26N2O5, CAS 17766-68-6
(4-(2-Methoxyphenyl)-1-piperazinyl)(3,4,5-trimethoxyphenyl)methanone
CAS 17766-68-6C21H26N2O5
Ketone, 4-(p-methoxyphenyl)piperazinyl 3,4,5-trimethoxyphenyl chemical structure, C21H26N2O5, CAS 17766-70-0
Ketone, 4-(p-methoxyphenyl)piperazinyl 3,4,5-trimethoxyphenyl
CAS 17766-70-0C21H26N2O5
Ketone, 4-(m-tolyl)piperazinyl 3,4,5-trimethoxyphenyl chemical structure, C21H26N2O4, CAS 17766-74-4
Ketone, 4-(m-tolyl)piperazinyl 3,4,5-trimethoxyphenyl
CAS 17766-74-4C21H26N2O4
Ketone, 4-(p-tolyl)piperazinyl 3,4,5-trimethoxyphenyl chemical structure, C21H26N2O4, CAS 17766-75-5
Ketone, 4-(p-tolyl)piperazinyl 3,4,5-trimethoxyphenyl
CAS 17766-75-5C21H26N2O4
Methanone, [4-[2,5-bis(1-methylethoxy)-4-nitrophenyl]-1-piperazinyl]phenyl- chemical structure, C23H29N3O5, CAS 68901-00-8
Methanone, [4-[2,5-bis(1-methylethoxy)-4-nitrophenyl]-1-piperazinyl]phenyl-
CAS 68901-00-8C23H29N3O5
[4-(2-Chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone chemical structure, C20H23ClN2O4, CAS 17766-64-2
[4-(2-Chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
CAS 17766-64-2C20H23ClN2O4
[4-(3-Chloro-2-methylphenyl)piperazin-1-yl](3,4,5-trimethoxyphenyl)methanone chemical structure, C21H25ClN2O4, CAS 6631-47-6
[4-(3-Chloro-2-methylphenyl)piperazin-1-yl](3,4,5-trimethoxyphenyl)methanone
CAS 6631-47-6C21H25ClN2O4
1-(2-Ethylphenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine chemical structure, C22H28N2O4, CAS 500532-47-8
1-(2-Ethylphenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
CAS 500532-47-8C22H28N2O4
1-Benzoyl-4-phenylpiperazine chemical structure, C17H18N2O, CAS 18907-52-3
1-Benzoyl-4-phenylpiperazine
CAS 18907-52-3C17H18N2O
[4-(2-Chlorophenyl)piperazin-1-yl](phenyl)methanone chemical structure, C17H17ClN2O, CAS 20386-34-9
[4-(2-Chlorophenyl)piperazin-1-yl](phenyl)methanone
CAS 20386-34-9C17H17ClN2O
(2-Chlorophenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C17H17ClN2O, CAS 314284-53-2
(2-Chlorophenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 314284-53-2C17H17ClN2O
1-(4-Chlorobenzoyl)-4-phenylpiperazine chemical structure, C17H17ClN2O, CAS 18907-57-8
1-(4-Chlorobenzoyl)-4-phenylpiperazine
CAS 18907-57-8C17H17ClN2O
(4-(3-Chloro-4-methylphenyl)piperazin-1-yl)(4-nitrophenyl)methanone chemical structure, C18H18ClN3O3, CAS 500584-95-2
(4-(3-Chloro-4-methylphenyl)piperazin-1-yl)(4-nitrophenyl)methanone
CAS 500584-95-2C18H18ClN3O3
[4-(4-Methylphenyl)-1-piperazinyl]phenylmethanone chemical structure, C18H20N2O, CAS 500294-67-7
[4-(4-Methylphenyl)-1-piperazinyl]phenylmethanone
CAS 500294-67-7C18H20N2O
[4-(3-Chlorophenyl)piperazin-1-yl]-phenylmethanone chemical structure, C17H17ClN2O, CAS 20011-17-0
[4-(3-Chlorophenyl)piperazin-1-yl]-phenylmethanone
CAS 20011-17-0C17H17ClN2O
1-(4-Nitrophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine chemical structure, C20H23N3O6, CAS 349116-90-1
1-(4-Nitrophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
CAS 349116-90-1C20H23N3O6
[4-(2-Chloro-6-nitro-phenyl)-piperazin-1-yl]-(2-fluoro-phenyl)-methanone chemical structure, C17H15ClFN3O3, CAS 347354-62-5
[4-(2-Chloro-6-nitro-phenyl)-piperazin-1-yl]-(2-fluoro-phenyl)-methanone
CAS 347354-62-5C17H15ClFN3O3
(2-Fluorophenyl)-[4-[4-nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]methanone chemical structure, C18H15F4N3O3, CAS 347354-63-6
(2-Fluorophenyl)-[4-[4-nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
CAS 347354-63-6C18H15F4N3O3
Piperazine, 1-(2,4-dichlorobenzoyl)-4-phenyl- chemical structure, C17H16Cl2N2O, CAS 306743-28-2
Piperazine, 1-(2,4-dichlorobenzoyl)-4-phenyl-
CAS 306743-28-2C17H16Cl2N2O
Piperazine, 1-(3,5-dimethoxybenzoyl)-4-phenyl- chemical structure, C19H22N2O3, CAS 333347-87-8
Piperazine, 1-(3,5-dimethoxybenzoyl)-4-phenyl-
CAS 333347-87-8C19H22N2O3
4-(Dimethylamino)phenyl 4-phenylpiperazinyl ketone chemical structure, C19H23N3O, CAS 333350-91-7
4-(Dimethylamino)phenyl 4-phenylpiperazinyl ketone
CAS 333350-91-7C19H23N3O
1-(2-Chloro-4,5-difluorobenzoyl)-4-phenylpiperazine chemical structure, C17H15ClF2N2O, CAS 332025-98-6
1-(2-Chloro-4,5-difluorobenzoyl)-4-phenylpiperazine
CAS 332025-98-6C17H15ClF2N2O