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Murcko scaffold

3-Phenyl-1-(pyrrolidin-1-yl)propan-1-one scaffold

216 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
216
With full pages
19
Scaffold SMILES

O=C(CCc1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1-(pyrrolidin-1-yl)propan-1-one page
Murcko scaffold O=C(CCc1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 216 chemicals

L-Prolinamide, N-methyl-D-phenylalanyl-N-((1S)-4-((aminoiminomethyl)amino)-1-formylbutyl)-, sulfate (1:1) chemical structure, C21H34N6O7S, CAS 126721-07-1
L-Prolinamide, N-methyl-D-phenylalanyl-N-((1S)-4-((aminoiminomethyl)amino)-1-formylbutyl)-, sulfate (1:1)
CAS 126721-07-1C21H34N6O7S
Pyrrolidine, 1-(o-hydroxyhydrocinnamoyl)- chemical structure, C13H17NO2, CAS 20862-56-0
Pyrrolidine, 1-(o-hydroxyhydrocinnamoyl)-
CAS 20862-56-0C13H17NO2
Tyrosyl-prolyl-leucyl-glycinamide chemical structure, C22H33N5O5, CAS 77133-61-0
Tyrosyl-prolyl-leucyl-glycinamide
CAS 77133-61-0C22H33N5O5
Efegatran chemical structure, C21H32N6O3, CAS 105806-65-3
Efegatran
CAS 105806-65-3C21H32N6O3
Dup 714 chemical structure, C21H33BN6O5, CAS 130982-43-3
Dup 714
CAS 130982-43-3C21H33BN6O5
H-D-Phe-Pro-arginal chemical structure, C20H30N6O3, CAS 60503-05-1
H-D-Phe-Pro-arginal
CAS 60503-05-1C20H30N6O3
Tyrosyl-prolyl-arginyl chloromethyl ketone chemical structure, C21H31ClN6O4, CAS 98833-79-5
Tyrosyl-prolyl-arginyl chloromethyl ketone
CAS 98833-79-5C21H31ClN6O4
Marinostatin D chemical structure, C43H66N12O17S, CAS 139113-32-9
Marinostatin D
CAS 139113-32-9C43H66N12O17S
N-Methylphenylalanyl-prolyl-arginine chemical structure, C21H32N6O4, CAS 162435-91-8
N-Methylphenylalanyl-prolyl-arginine
CAS 162435-91-8C21H32N6O4
Phenylalanyl-prolyl-arginine chemical structure, C20H30N6O4, CAS 79338-56-0
Phenylalanyl-prolyl-arginine
CAS 79338-56-0C20H30N6O4
Phenylalanyl-prolyl-alanine chemical structure, C17H23N3O4, CAS 81391-38-0
Phenylalanyl-prolyl-alanine
CAS 81391-38-0C17H23N3O4
Tyrosyl-prolyl-glycyl-glycine chemical structure, C18H24N4O6, CAS 85563-30-0
Tyrosyl-prolyl-glycyl-glycine
CAS 85563-30-0C18H24N4O6
Phenylalanylproline chemical structure, C14H18N2O3, CAS 51926-52-4
Phenylalanylproline
CAS 51926-52-4C14H18N2O3
Iodotyrosyl-prolyl-arginyl chloromethyl ketone chemical structure, C21H30ClIN6O4, CAS 126251-21-6
Iodotyrosyl-prolyl-arginyl chloromethyl ketone
CAS 126251-21-6C21H30ClIN6O4
1-Ethoxycarbonyl-D-phe-pro-2(4-aminobutyl)hydrazine chemical structure, C21H33N5O4, CAS 194292-87-0
1-Ethoxycarbonyl-D-phe-pro-2(4-aminobutyl)hydrazine
CAS 194292-87-0C21H33N5O4
(2S)-2-[[(2S)-1-[(2S)-2-Amino-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid chemical structure, C20H30N6O4, CAS 37553-80-3
(2S)-2-[[(2S)-1-[(2S)-2-Amino-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
CAS 37553-80-3C20H30N6O4
Ac-Glu-Asn-Tyr-Pro-Ile-NH2 chemical structure, C31H45N7O10, CAS 133683-36-0
Ac-Glu-Asn-Tyr-Pro-Ile-NH2
CAS 133683-36-0C31H45N7O10
HIV Protease Substrate VIII chemical structure, C42H66N10O13, CAS 118488-98-5
HIV Protease Substrate VIII
CAS 118488-98-5C42H66N10O13
Boc-Phe-Pro-OH chemical structure, C19H26N2O5, CAS 23420-32-8
Boc-Phe-Pro-OH
CAS 23420-32-8C19H26N2O5
Pyrrolidine, 1-[3-(4-methoxyphenyl)-1-oxopropyl]- chemical structure, C14H19NO2, CAS 56004-07-0
Pyrrolidine, 1-[3-(4-methoxyphenyl)-1-oxopropyl]-
CAS 56004-07-0C14H19NO2
3-(4-Aminophenyl)-1-(1-pyrrolidinyl)-1-propanone chemical structure, C13H18N2O, CAS 168897-22-1
3-(4-Aminophenyl)-1-(1-pyrrolidinyl)-1-propanone
CAS 168897-22-1C13H18N2O
3-Phenyl-1-(pyrrolidin-1-yl)propan-1-one chemical structure, C13H17NO, CAS 151647-54-0
3-Phenyl-1-(pyrrolidin-1-yl)propan-1-one
CAS 151647-54-0C13H17NO
Boc-D-phe-pro-OH chemical structure, C19H26N2O5, CAS 38675-10-4
Boc-D-phe-pro-OH
CAS 38675-10-4C19H26N2O5
2-Amino-3-phenyl-1-(pyrrolidin-1-yl)propan-1-one chemical structure, C13H18N2O, CAS 92008-59-8
2-Amino-3-phenyl-1-(pyrrolidin-1-yl)propan-1-one
CAS 92008-59-8C13H18N2O