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Murcko scaffold

1-Oxa-7-azaspiro(4.5)decane scaffold

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
40
With full pages
4
Scaffold SMILES

C1CNCC2(C1)CCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Oxa-7-azaspiro(4.5)decane page
Murcko scaffold C1CNCC2(C1)CCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

1-Oxa-7-azaspiro(4.5)decane chemical structure, C8H15NO, CAS 63766-56-3
1-Oxa-7-azaspiro(4.5)decane
CAS 63766-56-3C8H15NO
3,3-Difluoro-1-oxa-7-azaspiro[4.5]decane chemical structure, C8H13F2NO, CAS 1214875-13-4
3,3-Difluoro-1-oxa-7-azaspiro[4.5]decane
CAS 1214875-13-4C8H13F2NO
7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C14H23NO5, CAS 1160246-94-5
7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decane-3-carboxylic acid
CAS 1160246-94-5C14H23NO5
tert-Butyl 3-(aminomethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C14H26N2O3, CAS 1160247-18-6
tert-Butyl 3-(aminomethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 1160247-18-6C14H26N2O3
tert-Butyl 3-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C13H24N2O3, CAS 1263177-13-4
tert-Butyl 3-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 1263177-13-4C13H24N2O3
Rel-(2R,5R)-7-[(tert-butoxy)carbonyl]-1-oxa-7-azaspiro[4.5]decane-2-carboxylic acid chemical structure, C14H23NO5, CAS 1446012-29-8
Rel-(2R,5R)-7-[(tert-butoxy)carbonyl]-1-oxa-7-azaspiro[4.5]decane-2-carboxylic acid
CAS 1446012-29-8C14H23NO5
Rel-(2S,5R)-7-[(tert-butoxy)carbonyl]-1-oxa-7-azaspiro[4.5]decane-2-carboxylic acid chemical structure, C14H23NO5, CAS 1446012-31-2
Rel-(2S,5R)-7-[(tert-butoxy)carbonyl]-1-oxa-7-azaspiro[4.5]decane-2-carboxylic acid
CAS 1446012-31-2C14H23NO5
1-Oxa-7-azaspiro(4.5)decane-7-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester chemical structure, C13H23NO4, CAS 1331825-51-4
1-Oxa-7-azaspiro(4.5)decane-7-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester
CAS 1331825-51-4C13H23NO4
1-Oxa-7-azaspiro[4.5]decane hydrochloride chemical structure, C8H16ClNO, CAS 1415562-85-4
1-Oxa-7-azaspiro[4.5]decane hydrochloride
CAS 1415562-85-4C8H16ClNO
1-Oxa-7-azaspiro[4.5]Decane hemioxalate chemical structure, C18H32N2O6, CAS 1956354-47-4
1-Oxa-7-azaspiro[4.5]Decane hemioxalate
CAS 1956354-47-4C18H32N2O6
tert-Butyl (3S,5S)-3-hydroxy-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C13H23NO4, CAS 1445951-10-9
tert-Butyl (3S,5S)-3-hydroxy-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 1445951-10-9C13H23NO4
Racemic-(3R,5S)-tert-butyl 3-hydroxy-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C13H23NO4, CAS 1445951-75-6
Racemic-(3R,5S)-tert-butyl 3-hydroxy-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 1445951-75-6C13H23NO4
2-(7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decan-3-yl)acetic acid chemical structure, C15H25NO5, CAS 1422344-25-9
2-(7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decan-3-yl)acetic acid
CAS 1422344-25-9C15H25NO5
tert-Butyl 1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C13H23NO3, CAS 1341040-07-0
tert-Butyl 1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 1341040-07-0C13H23NO3
3-(Allyloxy)-1-oxa-7-azaspiro[4.5]decane chemical structure, C11H19NO2, CAS 1422059-39-9
3-(Allyloxy)-1-oxa-7-azaspiro[4.5]decane
CAS 1422059-39-9C11H19NO2
tert-Butyl 3-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate oxalate chemical structure, C15H26N2O7, CAS 2177258-11-4
tert-Butyl 3-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate oxalate
CAS 2177258-11-4C15H26N2O7
1-Oxa-7-azaspiro[4.5]decan-3-ol chemical structure, C8H15NO2, CAS 2000617-01-4
1-Oxa-7-azaspiro[4.5]decan-3-ol
CAS 2000617-01-4C8H15NO2
3-Fluoro-1-oxa-7-azaspiro[4.5]decane chemical structure, C8H14FNO, CAS 2168335-03-1
3-Fluoro-1-oxa-7-azaspiro[4.5]decane
CAS 2168335-03-1C8H14FNO
tert-Butyl 2-(hydroxymethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C14H25NO4, CAS 2937720-96-0
tert-Butyl 2-(hydroxymethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 2937720-96-0C14H25NO4
tert-Butyl 2-(aminomethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C14H26N2O3, CAS 2160849-48-7
tert-Butyl 2-(aminomethyl)-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 2160849-48-7C14H26N2O3
7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decane-2-carboxylic acid chemical structure, C14H23NO5, CAS 2967478-30-2
7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decane-2-carboxylic acid
CAS 2967478-30-2C14H23NO5
7-[(tert-Butoxy)carbonyl]-1-oxa-7-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C14H23NO5, CAS 2137886-21-4
7-[(tert-Butoxy)carbonyl]-1-oxa-7-azaspiro[4.5]decane-4-carboxylic acid
CAS 2137886-21-4C14H23NO5
tert-Butyl 4-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C13H24N2O3, CAS 2137446-47-8
tert-Butyl 4-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 2137446-47-8C13H24N2O3
tert-Butyl 4-cyano-1-oxa-7-azaspiro[4.5]decane-7-carboxylate chemical structure, C14H22N2O3, CAS 2137675-73-9
tert-Butyl 4-cyano-1-oxa-7-azaspiro[4.5]decane-7-carboxylate
CAS 2137675-73-9C14H22N2O3