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Murcko scaffold

RefChem:381633 scaffold

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
21
With full pages
5
Scaffold SMILES

O=C1CC(=Nc2ccccc2)NN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the RefChem:381633 page
Murcko scaffold O=C1CC(=Nc2ccccc2)NN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

3H-Pyrazol-3-one, 2,4-dihydro-5-((4-nitrophenyl)amino)-2-(2,4,6-trichlorophenyl)- chemical structure, C15H9Cl3N4O3, CAS 34320-82-6
3H-Pyrazol-3-one, 2,4-dihydro-5-((4-nitrophenyl)amino)-2-(2,4,6-trichlorophenyl)-
CAS 34320-82-6C15H9Cl3N4O3
3H-Pyrazol-3-one, 5-[(5-amino-2-chlorophenyl)amino]-2,4-dihydro-2-(2,4,6-trichlorophenyl)- chemical structure, C15H10Cl4N4O, CAS 53411-33-9
3H-Pyrazol-3-one, 5-[(5-amino-2-chlorophenyl)amino]-2,4-dihydro-2-(2,4,6-trichlorophenyl)-
CAS 53411-33-9C15H10Cl4N4O
Tetradecanamide, N-[4-chloro-3-[[4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]amino]phenyl]- chemical structure, C29H36Cl4N4O2, CAS 54636-84-9
Tetradecanamide, N-[4-chloro-3-[[4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]amino]phenyl]-
CAS 54636-84-9C29H36Cl4N4O2
3-(2-Chloro-5-nitroanilino)-1-(2,4,6-trichlorophenyl)pyrazolone chemical structure, C15H8Cl4N4O3, CAS 30707-68-7
3-(2-Chloro-5-nitroanilino)-1-(2,4,6-trichlorophenyl)pyrazolone
CAS 30707-68-7C15H8Cl4N4O3
5-[(4-Methoxyphenyl)amino]-2-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C16H15N3O2, CAS 7186-67-6
5-[(4-Methoxyphenyl)amino]-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 7186-67-6C16H15N3O2
3-(3-Aminophenylamino)-1-phenyl-2-pyrazolin-5-one chemical structure, C15H14N4O, CAS 94906-63-5
3-(3-Aminophenylamino)-1-phenyl-2-pyrazolin-5-one
CAS 94906-63-5C15H14N4O
3H-Pyrazol-3-one, 5-((2,4-dichlorophenyl)amino)-2,4-dihydro-2-(2,4,6-trichlorophenyl)- chemical structure, C15H8Cl5N3O, CAS 3182-02-3
3H-Pyrazol-3-one, 5-((2,4-dichlorophenyl)amino)-2,4-dihydro-2-(2,4,6-trichlorophenyl)-
CAS 3182-02-3C15H8Cl5N3O
RefChem:381633 chemical structure, C15H13N3O, CAS 7186-66-5
RefChem:381633
CAS 7186-66-5C15H13N3O
3-(3-Chlorophenylamino)-1-phenyl-2-pyrazolin-5-one chemical structure, C15H12ClN3O, CAS 7337-01-1
3-(3-Chlorophenylamino)-1-phenyl-2-pyrazolin-5-one
CAS 7337-01-1C15H12ClN3O
4-Chloro-3-((1-(2,6-dichloro-4-(methylsulphonyl)phenyl)-4,5-dihydro-5-oxo-1H-pyrazol-3-yl)amino)-N-hexadecyl-N-methylbenzamide chemical structure, C34H47Cl3N4O4S, CAS 61138-44-1
4-Chloro-3-((1-(2,6-dichloro-4-(methylsulphonyl)phenyl)-4,5-dihydro-5-oxo-1H-pyrazol-3-yl)amino)-N-hexadecyl-N-methylbenzamide
CAS 61138-44-1C34H47Cl3N4O4S
2-[2-(2-Chloro-1,1,2-trifluoroethoxy)phenyl]-5-[[4-(hexadecylsulphonyl)phenyl]amino]-2,4-dihydro-3H-pyrazol-3-one chemical structure, C33H45ClF3N3O4S, CAS 84100-61-8
2-[2-(2-Chloro-1,1,2-trifluoroethoxy)phenyl]-5-[[4-(hexadecylsulphonyl)phenyl]amino]-2,4-dihydro-3H-pyrazol-3-one
CAS 84100-61-8C33H45ClF3N3O4S
N-[4-Chloro-3-[[4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]amino]phenyl]pentadecanamide chemical structure, C30H38Cl4N4O2, CAS 85204-35-9
N-[4-Chloro-3-[[4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]amino]phenyl]pentadecanamide
CAS 85204-35-9C30H38Cl4N4O2
3H-Pyrazol-3-one,2,4-dihydro-5-[(4-methoxyphenyl)amino]-2-(4-nitrophenyl)- chemical structure, C16H14N4O4, CAS 7188-82-1
3H-Pyrazol-3-one,2,4-dihydro-5-[(4-methoxyphenyl)amino]-2-(4-nitrophenyl)-
CAS 7188-82-1C16H14N4O4
Hexadecyl (4-chloro-3-((4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl)amino)phenyl)carbamate chemical structure, C32H42Cl4N4O3, CAS 57233-79-1
Hexadecyl (4-chloro-3-((4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl)amino)phenyl)carbamate
CAS 57233-79-1C32H42Cl4N4O3
3H-Pyrazol-3-one, 5-[(4-aminophenyl)amino]-2,4-dihydro-2-(2,4,6-trichlorophenyl)- chemical structure, C15H11Cl3N4O, CAS 63450-50-0
3H-Pyrazol-3-one, 5-[(4-aminophenyl)amino]-2,4-dihydro-2-(2,4,6-trichlorophenyl)-
CAS 63450-50-0C15H11Cl3N4O
5-(4-Chloroanilino)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H12ClN3O, CAS 7186-69-8
5-(4-Chloroanilino)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 7186-69-8C15H12ClN3O
3H-Pyrazol-3-one,2,4-dihydro-5-[(2-methoxyphenyl)amino]-2-(4-nitrophenyl)- chemical structure, C16H14N4O4, CAS 5041-43-0
3H-Pyrazol-3-one,2,4-dihydro-5-[(2-methoxyphenyl)amino]-2-(4-nitrophenyl)-
CAS 5041-43-0C16H14N4O4
3H-Pyrazol-3-one,2,4-dihydro-5-[(4-methylphenyl)amino]-2-phenyl- chemical structure, C16H15N3O, CAS 7186-68-7
3H-Pyrazol-3-one,2,4-dihydro-5-[(4-methylphenyl)amino]-2-phenyl-
CAS 7186-68-7C16H15N3O
5-(3-Nitroanilino)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C15H12N4O3, CAS 7337-03-3
5-(3-Nitroanilino)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 7337-03-3C15H12N4O3
3H-Pyrazol-3-one,2,4-dihydro-5-[(2-methylphenyl)amino]-2-phenyl- chemical structure, C16H15N3O, CAS 7337-18-0
3H-Pyrazol-3-one,2,4-dihydro-5-[(2-methylphenyl)amino]-2-phenyl-
CAS 7337-18-0C16H15N3O
2,4-Dihydro-2-(4-nitrophenyl)-5-(phenylamino)-3H-pyrazol-3-one chemical structure, C15H12N4O3, CAS 30707-70-1
2,4-Dihydro-2-(4-nitrophenyl)-5-(phenylamino)-3H-pyrazol-3-one
CAS 30707-70-1C15H12N4O3