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Murcko scaffold

Ring system with 3 rings and 23 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
19
With full pages
5
Scaffold SMILES

O=S(=O)(NCCc1cnc(-c2cccnc2)s1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCCc1cnc(-c2cccnc2)s1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-Fluoro-4-methoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C18H18FN3O3S2, CAS 869069-74-9
2-Fluoro-4-methoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 869069-74-9C18H18FN3O3S2
4-Fluoro-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C17H16FN3O2S2, CAS 869069-75-0
4-Fluoro-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 869069-75-0C17H16FN3O2S2
2,4,6-Trimethyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C20H23N3O2S2, CAS 869069-76-1
2,4,6-Trimethyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 869069-76-1C20H23N3O2S2
4-Methoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C18H19N3O3S2, CAS 869069-77-2
4-Methoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 869069-77-2C18H19N3O3S2
3,4-Dimethoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C19H21N3O4S2, CAS 869069-81-8
3,4-Dimethoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 869069-81-8C19H21N3O4S2
2,5-Dimethoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C19H21N3O4S2, CAS 869069-82-9
2,5-Dimethoxy-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 869069-82-9C19H21N3O4S2
N-(2-(4-Methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)benzenesulfonamide chemical structure, C17H17N3O2S2, CAS 873009-98-4
N-(2-(4-Methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)benzenesulfonamide
CAS 873009-98-4C17H17N3O2S2
2,5-Difluoro-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C17H15F2N3O2S2, CAS 873009-93-9
2,5-Difluoro-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 873009-93-9C17H15F2N3O2S2
N-[2-(4-Methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]-3-nitrobenzenesulfonamide chemical structure, C17H16N4O4S2, CAS 873009-94-0
N-[2-(4-Methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]-3-nitrobenzenesulfonamide
CAS 873009-94-0C17H16N4O4S2
2,4,5-Trimethyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C20H23N3O2S2, CAS 873009-96-2
2,4,5-Trimethyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 873009-96-2C20H23N3O2S2
3,4-Dimethyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C19H21N3O2S2, CAS 873009-97-3
3,4-Dimethyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 873009-97-3C19H21N3O2S2
4-Chloro-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C17H16ClN3O2S2, CAS 873010-00-5
4-Chloro-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 873010-00-5C17H16ClN3O2S2
4-Methyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C18H19N3O2S2, CAS 873010-02-7
4-Methyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 873010-02-7C18H19N3O2S2
4-Methoxy-3-methyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide chemical structure, C19H21N3O3S2, CAS 873010-05-0
4-Methoxy-3-methyl-N-[2-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)ethyl]benzenesulfonamide
CAS 873010-05-0C19H21N3O3S2
2-Fluoro-N-(2-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)benzenesulfonamide chemical structure, C17H16FN3O2S2, CAS 873010-06-1
2-Fluoro-N-(2-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)benzenesulfonamide
CAS 873010-06-1C17H16FN3O2S2
4-Fluoro-N-(2-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)-3-(trifluoromethyl)benzenesulfonamide chemical structure, C18H15F4N3O2S2, CAS 873010-04-9
4-Fluoro-N-(2-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)-3-(trifluoromethyl)benzenesulfonamide
CAS 873010-04-9C18H15F4N3O2S2
4-Iodo-N-{2-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]ethyl}benzene-1-sulfonamide chemical structure, C17H16IN3O2S2, CAS 873009-95-1
4-Iodo-N-{2-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]ethyl}benzene-1-sulfonamide
CAS 873009-95-1C17H16IN3O2S2
4-Bromo-N-{2-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]ethyl}benzene-1-sulfonamide chemical structure, C17H16BrN3O2S2, CAS 873009-99-5
4-Bromo-N-{2-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]ethyl}benzene-1-sulfonamide
CAS 873009-99-5C17H16BrN3O2S2
2,5-Dichloro-N-(2-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)benzenesulfonamide chemical structure, C17H15Cl2N3O2S2, CAS 873010-01-6
2,5-Dichloro-N-(2-(4-methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl)benzenesulfonamide
CAS 873010-01-6C17H15Cl2N3O2S2