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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,105 to 1,152 of 19,000 chemicals

4-Chloro-6-hydrazinyl-2-(methylsulfanyl)pyrimidine chemical structure, C5H7ClN4S, CAS 89280-24-0
4-Chloro-6-hydrazinyl-2-(methylsulfanyl)pyrimidine
CAS 89280-24-0C5H7ClN4S
2-((6-Chloro-2-(methylsulfanyl)-4-pyrimidinyl)(2-hydroxyethyl)amino)-1-ethanol chemical structure, C9H14ClN3O2S, CAS 339017-88-8
2-((6-Chloro-2-(methylsulfanyl)-4-pyrimidinyl)(2-hydroxyethyl)amino)-1-ethanol
CAS 339017-88-8C9H14ClN3O2S
N-Methyl-2-methylsulfanyl-6-(trifluoromethyl)pyrimidin-4-amine chemical structure, C7H8F3N3S, CAS 339019-60-2
N-Methyl-2-methylsulfanyl-6-(trifluoromethyl)pyrimidin-4-amine
CAS 339019-60-2C7H8F3N3S
Ethyl 2-methyl-4-(trifluoromethyl)pyrimidine-5-carboxylate chemical structure, C9H9F3N2O2, CAS 149771-10-8
Ethyl 2-methyl-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS 149771-10-8C9H9F3N2O2
2-Amino-4-(trifluoromethyl)pyrimidine-5-carbonitrile chemical structure, C6H3F3N4, CAS 400088-04-2
2-Amino-4-(trifluoromethyl)pyrimidine-5-carbonitrile
CAS 400088-04-2C6H3F3N4
6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine chemical structure, C6H8ClN3S, CAS 478258-67-2
6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine
CAS 478258-67-2C6H8ClN3S
N~2~,N~2~-dimethyl-5-(methylsulfonyl)-2,4-pyrimidinediamine chemical structure, C7H12N4O2S, CAS 339108-23-5
N~2~,N~2~-dimethyl-5-(methylsulfonyl)-2,4-pyrimidinediamine
CAS 339108-23-5C7H12N4O2S
4,6-Dichloro-N-methyl-5-(methylsulfanyl)-2-pyrimidinamine chemical structure, C6H7Cl2N3S, CAS 40765-72-8
4,6-Dichloro-N-methyl-5-(methylsulfanyl)-2-pyrimidinamine
CAS 40765-72-8C6H7Cl2N3S
Ethyl 4-[(cyanomethyl)(methyl)amino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate chemical structure, C11H14N4O2S, CAS 860788-08-5
Ethyl 4-[(cyanomethyl)(methyl)amino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate
CAS 860788-08-5C11H14N4O2S
4-Chloro-5-iodo-2,6-dimethylpyrimidine chemical structure, C6H6ClIN2, CAS 83410-16-6
4-Chloro-5-iodo-2,6-dimethylpyrimidine
CAS 83410-16-6C6H6ClIN2
4-Bromomethyl-2-methylthiopyrimidine chemical structure, C6H7BrN2S, CAS 135645-63-5
4-Bromomethyl-2-methylthiopyrimidine
CAS 135645-63-5C6H7BrN2S
Diethyl 2-((2-pyrimidinylamino)methylene)malonate chemical structure, C12H15N3O4, CAS 21025-62-7
Diethyl 2-((2-pyrimidinylamino)methylene)malonate
CAS 21025-62-7C12H15N3O4
2-(6-Methyl-2-methylsulfanylpyrimidin-4-yl)sulfanylethanol chemical structure, C8H12N2OS2, CAS 202746-13-2
2-(6-Methyl-2-methylsulfanylpyrimidin-4-yl)sulfanylethanol
CAS 202746-13-2C8H12N2OS2
4-Amino-2-cyanomethylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester chemical structure, C9H10N4O2S, CAS 333415-86-4
4-Amino-2-cyanomethylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
CAS 333415-86-4C9H10N4O2S
Ethanol, 2-[[6-methyl-2-(methylthio)-4-pyrimidinyl]oxy]- chemical structure, C8H12N2O2S, CAS 112010-51-2
Ethanol, 2-[[6-methyl-2-(methylthio)-4-pyrimidinyl]oxy]-
CAS 112010-51-2C8H12N2O2S
4-[(4,6-Dimethylpyrimidin-2-yl)amino]butanoic acid chemical structure, C10H15N3O2, CAS 139399-51-2
4-[(4,6-Dimethylpyrimidin-2-yl)amino]butanoic acid
CAS 139399-51-2C10H15N3O2
2-[(4,6-Dimethyl-2-pyrimidinyl)amino]-ethanol chemical structure, C8H13N3O, CAS 1742-29-6
2-[(4,6-Dimethyl-2-pyrimidinyl)amino]-ethanol
CAS 1742-29-6C8H13N3O
3-[(4,6-Dimethylpyrimidin-2-yl)amino]propan-1-ol chemical structure, C9H15N3O, CAS 126085-68-5
3-[(4,6-Dimethylpyrimidin-2-yl)amino]propan-1-ol
CAS 126085-68-5C9H15N3O
4-Chloro-6-propoxypyrimidin-2-amine chemical structure, C7H10ClN3O, CAS 100763-69-7
4-Chloro-6-propoxypyrimidin-2-amine
CAS 100763-69-7C7H10ClN3O
2-(Methylsulfanyl)-6-(octyloxy)pyrimidin-4-ylamine chemical structure, C13H23N3OS, CAS 887570-27-6
2-(Methylsulfanyl)-6-(octyloxy)pyrimidin-4-ylamine
CAS 887570-27-6C13H23N3OS
[5,6-Diamino-2-(sulfanylmethyl)pyrimidin-4-yl]methanethiol chemical structure, C6H10N4S2, CAS 887571-02-0
[5,6-Diamino-2-(sulfanylmethyl)pyrimidin-4-yl]methanethiol
CAS 887571-02-0C6H10N4S2
Prop-2-ynyl pyrimidine-4-carboxylate chemical structure, C8H6N2O2, CAS 887582-76-5
Prop-2-ynyl pyrimidine-4-carboxylate
CAS 887582-76-5C8H6N2O2
2-Chloro-N-ethyl-5-fluoropyrimidin-4-amine chemical structure, C6H7ClFN3, CAS 321529-80-0
2-Chloro-N-ethyl-5-fluoropyrimidin-4-amine
CAS 321529-80-0C6H7ClFN3
2,4,6-Trifluoro-5-methylpyrimidine chemical structure, C5H3F3N2, CAS 18260-60-1
2,4,6-Trifluoro-5-methylpyrimidine
CAS 18260-60-1C5H3F3N2