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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,297 to 1,344 of 19,000 chemicals

4-(Difluoromethoxy)-6-methylpyrimidin-2-amine chemical structure, C6H7F2N3O, CAS 85821-30-3
4-(Difluoromethoxy)-6-methylpyrimidin-2-amine
CAS 85821-30-3C6H7F2N3O
N4-(sec-butyl)-5-nitropyrimidine-4,6-diamine chemical structure, C8H13N5O2, CAS 201992-14-5
N4-(sec-butyl)-5-nitropyrimidine-4,6-diamine
CAS 201992-14-5C8H13N5O2
4,6-Dimethoxy-5-methylpyrimidine chemical structure, C7H10N2O2, CAS 13566-63-7
4,6-Dimethoxy-5-methylpyrimidine
CAS 13566-63-7C7H10N2O2
4,6-Dimethoxypyrimidin-5-amine chemical structure, C6H9N3O2, CAS 15846-15-8
4,6-Dimethoxypyrimidin-5-amine
CAS 15846-15-8C6H9N3O2
2-Pyrimidinesulfonic acid chemical structure, C4H4N2O3S, CAS 34916-79-5
2-Pyrimidinesulfonic acid
CAS 34916-79-5C4H4N2O3S
2,2-Dimethyl-N-[2,2,2-trichloro-1-[2-[2,2,2-trichloro-1-(2,2-dimethylpropanoylamino)ethyl]sulfanylpyrimidin-4-yl]sulfanylethyl]propanamide chemical structure, C18H24Cl6N4O2S2, CAS 162331-18-2
2,2-Dimethyl-N-[2,2,2-trichloro-1-[2-[2,2,2-trichloro-1-(2,2-dimethylpropanoylamino)ethyl]sulfanylpyrimidin-4-yl]sulfanylethyl]propanamide
CAS 162331-18-2C18H24Cl6N4O2S2
4,6-Bis(tert-butylamino)-5-nitropyrimidine chemical structure, C12H21N5O2, CAS 25710-27-4
4,6-Bis(tert-butylamino)-5-nitropyrimidine
CAS 25710-27-4C12H21N5O2
2-[Cyano-(4,6-dimethylpyrimidin-2-yl)amino]-N,N-dimethylpropanamide chemical structure, C12H17N5O, CAS 302332-34-9
2-[Cyano-(4,6-dimethylpyrimidin-2-yl)amino]-N,N-dimethylpropanamide
CAS 302332-34-9C12H17N5O
2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-butyric acid chemical structure, C10H14N2O2S, CAS 433242-64-9
2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-butyric acid
CAS 433242-64-9C10H14N2O2S
2-((4,6-Dimethylpyrimidin-2-yl)thio)hexanoic acid chemical structure, C12H18N2O2S, CAS 127013-13-2
2-((4,6-Dimethylpyrimidin-2-yl)thio)hexanoic acid
CAS 127013-13-2C12H18N2O2S
4-N-Butyl-5-nitropyrimidine-4,6-diamine chemical structure, C8H13N5O2, CAS 90641-93-3
4-N-Butyl-5-nitropyrimidine-4,6-diamine
CAS 90641-93-3C8H13N5O2
2-[(6-Amino-5-nitropyrimidin-4-yl)amino]butan-1-ol chemical structure, C8H13N5O3, CAS 450344-83-9
2-[(6-Amino-5-nitropyrimidin-4-yl)amino]butan-1-ol
CAS 450344-83-9C8H13N5O3
2-(2-((6-Amino-5-nitropyrimidin-4-yl)amino)ethoxy)ethanol chemical structure, C8H13N5O4, CAS 450344-75-9
2-(2-((6-Amino-5-nitropyrimidin-4-yl)amino)ethoxy)ethanol
CAS 450344-75-9C8H13N5O4
Ethyl 2-((6-amino-5-nitropyrimidin-4-yl)amino)acetate chemical structure, C8H11N5O4, CAS 22386-74-9
Ethyl 2-((6-amino-5-nitropyrimidin-4-yl)amino)acetate
CAS 22386-74-9C8H11N5O4
N4-(2-(Diethylamino)ethyl)-5-nitropyrimidine-4,6-diamine chemical structure, C10H18N6O2, CAS 450344-81-7
N4-(2-(Diethylamino)ethyl)-5-nitropyrimidine-4,6-diamine
CAS 450344-81-7C10H18N6O2
N-(1-Methoxypropan-2-yl)-5-nitropyrimidine-4,6-diamine chemical structure, C8H13N5O3, CAS 450344-73-7
N-(1-Methoxypropan-2-yl)-5-nitropyrimidine-4,6-diamine
CAS 450344-73-7C8H13N5O3
N4-(3-methoxypropyl)-5-nitropyrimidine-4,6-diamine chemical structure, C8H13N5O3, CAS 450344-69-1
N4-(3-methoxypropyl)-5-nitropyrimidine-4,6-diamine
CAS 450344-69-1C8H13N5O3
N4-isobutyl-5-nitropyrimidine-4,6-diamine chemical structure, C8H13N5O2, CAS 450344-68-0
N4-isobutyl-5-nitropyrimidine-4,6-diamine
CAS 450344-68-0C8H13N5O2
4-N-[3-(Dimethylamino)propyl]-5-nitropyrimidine-4,6-diamine chemical structure, C9H16N6O2, CAS 102540-82-9
4-N-[3-(Dimethylamino)propyl]-5-nitropyrimidine-4,6-diamine
CAS 102540-82-9C9H16N6O2
2-[(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)thio]acetamide chemical structure, C8H11N3O2S, CAS 890641-01-7
2-[(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)thio]acetamide
CAS 890641-01-7C8H11N3O2S
2-Ethyl-5-(methoxymethyl)-4-pyrimidinamine chemical structure, C8H13N3O, CAS 49781-38-6
2-Ethyl-5-(methoxymethyl)-4-pyrimidinamine
CAS 49781-38-6C8H13N3O
5-Methylpyrimidine-2,4,6-triamine chemical structure, C5H9N5, CAS 71735-34-7
5-Methylpyrimidine-2,4,6-triamine
CAS 71735-34-7C5H9N5
Ethyl 4-chloro-2-ethoxypyrimidine-5-carboxylate chemical structure, C9H11ClN2O3, CAS 79614-52-1
Ethyl 4-chloro-2-ethoxypyrimidine-5-carboxylate
CAS 79614-52-1C9H11ClN2O3
4-Pyrimidinamine, 6-chloro-5-nitro-N-2-propenyl- chemical structure, C7H7ClN4O2, CAS 89793-34-0
4-Pyrimidinamine, 6-chloro-5-nitro-N-2-propenyl-
CAS 89793-34-0C7H7ClN4O2