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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,249 to 1,296 of 19,000 chemicals

1-(2,6-Dimethylpyrimidin-4-yl)thiourea chemical structure, C7H10N4S, CAS 1913-09-3
1-(2,6-Dimethylpyrimidin-4-yl)thiourea
CAS 1913-09-3C7H10N4S
4-Methyl-2-(methylsulfonyl)pyrimidine chemical structure, C6H8N2O2S, CAS 77166-01-9
4-Methyl-2-(methylsulfonyl)pyrimidine
CAS 77166-01-9C6H8N2O2S
4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine chemical structure, C7H10N2O3S, CAS 57268-32-3
4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine
CAS 57268-32-3C7H10N2O3S
4,6-Dimethyl-2-methylsulfonylpyrimidine chemical structure, C7H10N2O2S, CAS 35144-22-0
4,6-Dimethyl-2-methylsulfonylpyrimidine
CAS 35144-22-0C7H10N2O2S
2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-propionic acid chemical structure, C9H12N2O2S, CAS 433242-31-0
2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-propionic acid
CAS 433242-31-0C9H12N2O2S
2-(4,6-Diaminopyrimidin-2-ylsulfanyl)-propionic acid chemical structure, C7H10N4O2S, CAS 347341-51-9
2-(4,6-Diaminopyrimidin-2-ylsulfanyl)-propionic acid
CAS 347341-51-9C7H10N4O2S
4-Chloro-6-(1-methylethyl)-2-pyrimidinamine chemical structure, C7H10ClN3, CAS 73576-33-7
4-Chloro-6-(1-methylethyl)-2-pyrimidinamine
CAS 73576-33-7C7H10ClN3
2-Chloro-4-(trifluoromethyl)pyrimidine chemical structure, C5H2ClF3N2, CAS 33034-67-2
2-Chloro-4-(trifluoromethyl)pyrimidine
CAS 33034-67-2C5H2ClF3N2
5-Pyrimidinecarboxylic acid, 2-hydrazinyl-4-(trifluoromethyl)-, methyl ester chemical structure, C7H7F3N4O2, CAS 175137-28-7
5-Pyrimidinecarboxylic acid, 2-hydrazinyl-4-(trifluoromethyl)-, methyl ester
CAS 175137-28-7C7H7F3N4O2
6-(tert-Butyl)pyrimidine-2,4-diamine chemical structure, C8H14N4, CAS 175137-26-5
6-(tert-Butyl)pyrimidine-2,4-diamine
CAS 175137-26-5C8H14N4
Ethyl 2-amino-4-propylpyrimidine-5-carboxylate chemical structure, C10H15N3O2, CAS 127957-83-9
Ethyl 2-amino-4-propylpyrimidine-5-carboxylate
CAS 127957-83-9C10H15N3O2
N1-(4-(Trifluoromethyl)pyrimidin-2-yl)ethane-1,2-diamine chemical structure, C7H9F3N4, CAS 215655-29-1
N1-(4-(Trifluoromethyl)pyrimidin-2-yl)ethane-1,2-diamine
CAS 215655-29-1C7H9F3N4
5-(tert-Butylsulfonyl)-2-methylpyrimidin-4-amine chemical structure, C9H15N3O2S, CAS 175201-85-1
5-(tert-Butylsulfonyl)-2-methylpyrimidin-4-amine
CAS 175201-85-1C9H15N3O2S
3-[(4-Chloro-6-methylpyrimidin-2-yl)amino]-2-(propylsulfonyl)acrylonitrile chemical structure, C11H13ClN4O2S, CAS 649664-59-5
3-[(4-Chloro-6-methylpyrimidin-2-yl)amino]-2-(propylsulfonyl)acrylonitrile
CAS 649664-59-5C11H13ClN4O2S
2-Methyl-5-(propylsulfonyl)pyrimidin-4-amine chemical structure, C8H13N3O2S, CAS 175202-09-2
2-Methyl-5-(propylsulfonyl)pyrimidin-4-amine
CAS 175202-09-2C8H13N3O2S
5-(2-Methylpropane-2-sulfonyl)pyrimidine-2,4-diamine chemical structure, C8H14N4O2S, CAS 175202-17-2
5-(2-Methylpropane-2-sulfonyl)pyrimidine-2,4-diamine
CAS 175202-17-2C8H14N4O2S
6-Chloro-N-methyl-5-nitro-4-pyrimidinamine chemical structure, C5H5ClN4O2, CAS 23126-82-1
6-Chloro-N-methyl-5-nitro-4-pyrimidinamine
CAS 23126-82-1C5H5ClN4O2
Methyl 2-[2-(2,3,3-trichloroacryloyl)hydrazino]-4-(trifluoromethyl)pyrimidine-5-carboxylate chemical structure, C10H6Cl3F3N4O3, CAS 648859-28-3
Methyl 2-[2-(2,3,3-trichloroacryloyl)hydrazino]-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS 648859-28-3C10H6Cl3F3N4O3
Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate chemical structure, C8H6ClF3N2O2, CAS 187035-79-6
Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS 187035-79-6C8H6ClF3N2O2
Ethyl 2-hydrazino-4-(trifluoromethyl)pyrimidine-5-carboxylate chemical structure, C8H9F3N4O2, CAS 188936-10-9
Ethyl 2-hydrazino-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS 188936-10-9C8H9F3N4O2
Ethyl 2-[2-(2-chloroacetyl)hydrazino]-4-(trifluoromethyl)-5-pyrimidinecarboxylate chemical structure, C10H10ClF3N4O3, CAS 648859-91-0
Ethyl 2-[2-(2-chloroacetyl)hydrazino]-4-(trifluoromethyl)-5-pyrimidinecarboxylate
CAS 648859-91-0C10H10ClF3N4O3
Ethyl 2-oxo-2-{2-[4-(trifluoromethyl)pyrimidin-2-yl]hydrazino}acetate chemical structure, C9H9F3N4O3, CAS 648427-25-2
Ethyl 2-oxo-2-{2-[4-(trifluoromethyl)pyrimidin-2-yl]hydrazino}acetate
CAS 648427-25-2C9H9F3N4O3
2-(Methylthio)-4-(trifluoromethyl)pyrimidine chemical structure, C6H5F3N2S, CAS 136547-20-1
2-(Methylthio)-4-(trifluoromethyl)pyrimidine
CAS 136547-20-1C6H5F3N2S
N4-butyl-6-fluoropyrimidine-2,4-diamine chemical structure, C8H13FN4, CAS 188987-77-1
N4-butyl-6-fluoropyrimidine-2,4-diamine
CAS 188987-77-1C8H13FN4