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Murcko scaffold

Ring system with 3 rings and 21 atoms

82 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
82
With full pages
7
Scaffold SMILES

O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

2-[5-(2-Fluorophenyl)-2H-tetrazol-2-yl]-N-(4-methoxyphenyl)acetamide chemical structure, C16H14FN5O2, CAS 505071-91-0
2-[5-(2-Fluorophenyl)-2H-tetrazol-2-yl]-N-(4-methoxyphenyl)acetamide
CAS 505071-91-0C16H14FN5O2
N-(3-Fluorophenyl)-2-[5-(2-fluorophenyl)tetrazol-2-yl]acetamide chemical structure, C15H11F2N5O, CAS 429644-09-7
N-(3-Fluorophenyl)-2-[5-(2-fluorophenyl)tetrazol-2-yl]acetamide
CAS 429644-09-7C15H11F2N5O
N-Ethyl-N-phenyl-2-(5-phenyl-2H-tetrazol-2-yl)acetamide chemical structure, C17H17N5O, CAS 693799-89-2
N-Ethyl-N-phenyl-2-(5-phenyl-2H-tetrazol-2-yl)acetamide
CAS 693799-89-2C17H17N5O
2-[5-(2-Chlorophenyl)tetrazol-2-yl]-N-(2,5-dimethylphenyl)acetamide chemical structure, C17H16ClN5O, CAS 385377-63-9
2-[5-(2-Chlorophenyl)tetrazol-2-yl]-N-(2,5-dimethylphenyl)acetamide
CAS 385377-63-9C17H16ClN5O
2-[5-(2-Chlorophenyl)tetrazol-2-yl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C16H11ClF3N5O, CAS 445410-11-7
2-[5-(2-Chlorophenyl)tetrazol-2-yl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 445410-11-7C16H11ClF3N5O
Ethyl 4-((2-(5-(2-methylphenyl)-2H-tetrazol-2-yl)acetyl)amino)benzoate chemical structure, C19H19N5O3, CAS 447411-93-0
Ethyl 4-((2-(5-(2-methylphenyl)-2H-tetrazol-2-yl)acetyl)amino)benzoate
CAS 447411-93-0C19H19N5O3
N-(2,3-Dimethylphenyl)-2-[5-(2-methylphenyl)tetrazol-2-yl]acetamide chemical structure, C18H19N5O, CAS 354125-06-7
N-(2,3-Dimethylphenyl)-2-[5-(2-methylphenyl)tetrazol-2-yl]acetamide
CAS 354125-06-7C18H19N5O
2-[5-(2-Fluoro-phenyl)-tetrazol-2-yl]-N-(2-methoxy-phenyl)-acetamide chemical structure, C16H14FN5O2, CAS 428503-07-5
2-[5-(2-Fluoro-phenyl)-tetrazol-2-yl]-N-(2-methoxy-phenyl)-acetamide
CAS 428503-07-5C16H14FN5O2
N-(2,4-Dimethylphenyl)-2-(5-phenyltetrazol-2-yl)acetamide chemical structure, C17H17N5O, CAS 337505-84-7
N-(2,4-Dimethylphenyl)-2-(5-phenyltetrazol-2-yl)acetamide
CAS 337505-84-7C17H17N5O
N-(4-Fluorophenyl)-2-[5-(2-methylphenyl)tetrazol-2-yl]acetamide chemical structure, C16H14FN5O, CAS 356088-81-8
N-(4-Fluorophenyl)-2-[5-(2-methylphenyl)tetrazol-2-yl]acetamide
CAS 356088-81-8C16H14FN5O
Acetamide, N-(2,4-difluorophenyl)-2-(5-p-tolyl-tetrazol-2-yl)- chemical structure, C16H13F2N5O, CAS 271775-47-4
Acetamide, N-(2,4-difluorophenyl)-2-(5-p-tolyl-tetrazol-2-yl)-
CAS 271775-47-4C16H13F2N5O
N-(3-Fluorophenyl)-2-[5-(4-methoxyphenyl)tetrazol-2-yl]acetamide chemical structure, C16H14FN5O2, CAS 429648-48-6
N-(3-Fluorophenyl)-2-[5-(4-methoxyphenyl)tetrazol-2-yl]acetamide
CAS 429648-48-6C16H14FN5O2
N-(2-Fluorophenyl)-2-(5-phenyltetrazol-2-yl)acetamide chemical structure, C15H12FN5O, CAS 317324-00-8
N-(2-Fluorophenyl)-2-(5-phenyltetrazol-2-yl)acetamide
CAS 317324-00-8C15H12FN5O
5-(2-Fluorophenyl)-N-phenyl-2H-tetrazole-2-acetamide chemical structure, C15H12FN5O, CAS 459795-82-5
5-(2-Fluorophenyl)-N-phenyl-2H-tetrazole-2-acetamide
CAS 459795-82-5C15H12FN5O
2-[5-(4-Fluorophenyl)tetrazol-2-yl]-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C18H18FN5O, CAS 335209-15-9
2-[5-(4-Fluorophenyl)tetrazol-2-yl]-N-(2,4,6-trimethylphenyl)acetamide
CAS 335209-15-9C18H18FN5O
2-(5-Phenyl-2H-tetrazol-2-yl)-N-(m-tolyl)acetamide chemical structure, C16H15N5O, CAS 337503-11-4
2-(5-Phenyl-2H-tetrazol-2-yl)-N-(m-tolyl)acetamide
CAS 337503-11-4C16H15N5O
N-(2-Methoxyphenyl)-2-(5-phenyltetrazol-2-yl)acetamide chemical structure, C16H15N5O2, CAS 337503-17-0
N-(2-Methoxyphenyl)-2-(5-phenyltetrazol-2-yl)acetamide
CAS 337503-17-0C16H15N5O2
N-(2,6-Dimethylphenyl)-2-(5-phenyltetrazol-2-yl)acetamide chemical structure, C17H17N5O, CAS 337503-37-4
N-(2,6-Dimethylphenyl)-2-(5-phenyltetrazol-2-yl)acetamide
CAS 337503-37-4C17H17N5O
N-(2,3-Dimethylphenyl)-2-(5-phenyl-2H-tetrazol-2-yl)acetamide chemical structure, C17H17N5O, CAS 337503-39-6
N-(2,3-Dimethylphenyl)-2-(5-phenyl-2H-tetrazol-2-yl)acetamide
CAS 337503-39-6C17H17N5O
N-(2-Methyl-5-nitrophenyl)-5-phenyl-2H-tetrazole-2-acetamide chemical structure, C16H14N6O3, CAS 337505-78-9
N-(2-Methyl-5-nitrophenyl)-5-phenyl-2H-tetrazole-2-acetamide
CAS 337505-78-9C16H14N6O3
N-(3,4-Dichlorophenyl)-2-(5-phenyl-2H-tetrazol-2-yl)acetamide chemical structure, C15H11Cl2N5O, CAS 337505-83-6
N-(3,4-Dichlorophenyl)-2-(5-phenyl-2H-tetrazol-2-yl)acetamide
CAS 337505-83-6C15H11Cl2N5O
2-[5-(4-Amino-phenyl)-tetrazol-2-yl]-N-phenyl-acetamide chemical structure, C15H14N6O, CAS 436092-99-8
2-[5-(4-Amino-phenyl)-tetrazol-2-yl]-N-phenyl-acetamide
CAS 436092-99-8C15H14N6O
N-(4-Ethylphenyl)-2-[5-(2-fluorophenyl)tetrazol-2-yl]acetamide chemical structure, C17H16FN5O, CAS 459822-49-2
N-(4-Ethylphenyl)-2-[5-(2-fluorophenyl)tetrazol-2-yl]acetamide
CAS 459822-49-2C17H16FN5O
N-(2-Methoxyphenyl)-2-[5-(4-methylphenyl)-2H-tetrazol-2-yl]acetamide chemical structure, C17H17N5O2, CAS 483974-68-1
N-(2-Methoxyphenyl)-2-[5-(4-methylphenyl)-2H-tetrazol-2-yl]acetamide
CAS 483974-68-1C17H17N5O2