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Murcko scaffold

Ring system with 3 rings and 18 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
15
With full pages
6
Scaffold SMILES

c1ccc(Nc2nc(-c3ccncc3)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc(-c3ccncc3)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-(4-Fluorophenyl)-4-(4-pyridinyl)-1,3-thiazol-2-amine chemical structure, C14H10FN3S, CAS 274249-44-4
N-(4-Fluorophenyl)-4-(4-pyridinyl)-1,3-thiazol-2-amine
CAS 274249-44-4C14H10FN3S
Stf-62247 chemical structure, C15H13N3S, CAS 315702-99-9
Stf-62247
CAS 315702-99-9C15H13N3S
N-(4-Methylphenyl)-4-(4-pyridinyl)-1,3-thiazol-2-amine chemical structure, C15H13N3S, CAS 5656-12-2
N-(4-Methylphenyl)-4-(4-pyridinyl)-1,3-thiazol-2-amine
CAS 5656-12-2C15H13N3S
RefChem:381551 chemical structure, C14H12N4S, CAS 5746-80-5
RefChem:381551
CAS 5746-80-5C14H12N4S
4-[(4-Pyridin-4-yl-1,3-thiazol-2-yl)amino]benzenesulfonamide chemical structure, C14H12N4O2S2, CAS 5744-46-7
4-[(4-Pyridin-4-yl-1,3-thiazol-2-yl)amino]benzenesulfonamide
CAS 5744-46-7C14H12N4O2S2
N-(4-Methoxyphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine chemical structure, C15H13N3OS, CAS 61889-63-2
N-(4-Methoxyphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine
CAS 61889-63-2C15H13N3OS
N-(4-Pyridin-4-YL-1,3-thiazol-2-yl)benzene-1,4-diamine hydrobromide chemical structure, C14H13BrN4S, CAS 1052530-79-6
N-(4-Pyridin-4-YL-1,3-thiazol-2-yl)benzene-1,4-diamine hydrobromide
CAS 1052530-79-6C14H13BrN4S
Methyl 3-(4-pyrid-4-ylthiazol-2-ylamino)benzoate chemical structure, C16H13N3O2S, CAS 294622-58-5
Methyl 3-(4-pyrid-4-ylthiazol-2-ylamino)benzoate
CAS 294622-58-5C16H13N3O2S
N-(3-Methylphenyl)-4-(2-methyl-4-pyridinyl)-1,3-thiazol-2-amine chemical structure, C16H15N3S, CAS 1187669-33-5
N-(3-Methylphenyl)-4-(2-methyl-4-pyridinyl)-1,3-thiazol-2-amine
CAS 1187669-33-5C16H15N3S
4-(3-Chloro-4-pyridinyl)-N-(3-methylphenyl)-1,3-thiazol-2-amine chemical structure, C15H12ClN3S, CAS 1187669-50-6
4-(3-Chloro-4-pyridinyl)-N-(3-methylphenyl)-1,3-thiazol-2-amine
CAS 1187669-50-6C15H12ClN3S
4-(3-Bromo-4-pyridinyl)-N-(3-methylphenyl)-1,3-thiazol-2-amine chemical structure, C15H12BrN3S, CAS 1187669-53-9
4-(3-Bromo-4-pyridinyl)-N-(3-methylphenyl)-1,3-thiazol-2-amine
CAS 1187669-53-9C15H12BrN3S
N-[4-(2-Amino-4-pyridinyl)-1,3-thiazol-2-yl]-N-(3-methylphenyl)amine chemical structure, C15H14N4S, CAS 1187669-59-5
N-[4-(2-Amino-4-pyridinyl)-1,3-thiazol-2-yl]-N-(3-methylphenyl)amine
CAS 1187669-59-5C15H14N4S
Jnj-1930942 chemical structure, C16H11F4N3OS, CAS 929562-28-7
Jnj-1930942
CAS 929562-28-7C16H11F4N3OS
4-Fluoro-2-{[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]amino}phenol chemical structure, C14H10FN3OS, CAS 1448324-33-1
4-Fluoro-2-{[4-(Pyridin-4-Yl)-1,3-Thiazol-2-Yl]amino}phenol
CAS 1448324-33-1C14H10FN3OS
1-N-[4-(Pyridin-4-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine chemical structure, C14H12N4S, CAS 1216155-71-3
1-N-[4-(Pyridin-4-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine
CAS 1216155-71-3C14H12N4S