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Murcko scaffold

2-(Piperazin-1-ylcarbonyl)-1H-indole scaffold

102 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
102
With full pages
13
Scaffold SMILES

O=C(c1cc2ccccc2[nH]1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperazin-1-ylcarbonyl)-1H-indole page
Murcko scaffold O=C(c1cc2ccccc2[nH]1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 102 chemicals

Piperazine, 1-((5-methoxyindol-2-yl)carbonyl)-4-methyl- chemical structure, C15H19N3O2, CAS 28837-78-7
Piperazine, 1-((5-methoxyindol-2-yl)carbonyl)-4-methyl-
CAS 28837-78-7C15H19N3O2
Piperazine, 1-((3-formyl-5-methoxyindol-2-yl)carbonyl)-4-methyl- chemical structure, C16H19N3O3, CAS 28837-84-5
Piperazine, 1-((3-formyl-5-methoxyindol-2-yl)carbonyl)-4-methyl-
CAS 28837-84-5C16H19N3O3
2-(Piperazin-1-ylcarbonyl)-1H-indole chemical structure, C13H15N3O, CAS 136818-95-6
2-(Piperazin-1-ylcarbonyl)-1H-indole
CAS 136818-95-6C13H15N3O
4-(1H-Indole-2-carbonyl)piperazine-1-carbaldehyde chemical structure, C14H15N3O2, CAS 1022130-34-2
4-(1H-Indole-2-carbonyl)piperazine-1-carbaldehyde
CAS 1022130-34-2C14H15N3O2
(1H-Indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H17N3O, CAS 73187-30-1
(1H-Indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 73187-30-1C14H17N3O
(5-Methyl-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone chemical structure, C15H19N3O, CAS 459168-44-6
(5-Methyl-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
CAS 459168-44-6C15H19N3O
Ethyl 4-(1H-indole-2-carbonyl)piperazine-1-carboxylate chemical structure, C16H19N3O3, CAS 1024061-54-8
Ethyl 4-(1H-indole-2-carbonyl)piperazine-1-carboxylate
CAS 1024061-54-8C16H19N3O3
Ethyl 4-(5-fluoro-1H-indole-2-carbonyl)piperazine-1-carboxylate chemical structure, C16H18FN3O3, CAS 902042-45-9
Ethyl 4-(5-fluoro-1H-indole-2-carbonyl)piperazine-1-carboxylate
CAS 902042-45-9C16H18FN3O3
Ethyl 4-(5-chloro-1H-indole-2-carbonyl)piperazine-1-carboxylate chemical structure, C16H18ClN3O3, CAS 904262-97-1
Ethyl 4-(5-chloro-1H-indole-2-carbonyl)piperazine-1-carboxylate
CAS 904262-97-1C16H18ClN3O3
(5-Fluoro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H16FN3O, CAS 459168-42-4
(5-Fluoro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 459168-42-4C14H16FN3O
Jnj-7777120 chemical structure, C14H16ClN3O, CAS 459168-41-3
Jnj-7777120
CAS 459168-41-3C14H16ClN3O
(4-Ethylpiperazin-1-yl)-(5-fluoro-1H-indol-2-yl)methanone chemical structure, C15H18FN3O, CAS 902305-11-7
(4-Ethylpiperazin-1-yl)-(5-fluoro-1H-indol-2-yl)methanone
CAS 902305-11-7C15H18FN3O
Ethyl 4-(6-methoxy-1H-indole-2-carbonyl)piperazine-1-carboxylate chemical structure, C17H21N3O4, CAS 900278-24-2
Ethyl 4-(6-methoxy-1H-indole-2-carbonyl)piperazine-1-carboxylate
CAS 900278-24-2C17H21N3O4
(4-Methylpiperazin-1-yl)-(4,5,6-trimethoxy-1H-indol-2-yl)methanone chemical structure, C17H23N3O4, CAS 902330-49-8
(4-Methylpiperazin-1-yl)-(4,5,6-trimethoxy-1H-indol-2-yl)methanone
CAS 902330-49-8C17H23N3O4
(5-Bromo-1H-indol-2-yl)(4-ethylpiperazin-1-yl)methanone chemical structure, C15H18BrN3O, CAS 898921-47-6
(5-Bromo-1H-indol-2-yl)(4-ethylpiperazin-1-yl)methanone
CAS 898921-47-6C15H18BrN3O
(4,5-Dimethoxy-1H-indol-2-yl)(piperazin-1-yl)methanone chemical structure, C15H19N3O3, CAS 899378-09-7
(4,5-Dimethoxy-1H-indol-2-yl)(piperazin-1-yl)methanone
CAS 899378-09-7C15H19N3O3
(5-Chloro-7-methyl-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C15H18ClN3O, CAS 669083-63-0
(5-Chloro-7-methyl-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 669083-63-0C15H18ClN3O
(7-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H16ClN3O, CAS 459168-46-8
(7-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 459168-46-8C14H16ClN3O
(5-Bromo-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H16BrN3O, CAS 459168-43-5
(5-Bromo-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 459168-43-5C14H16BrN3O
(6-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H16ClN3O, CAS 459168-49-1
(6-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 459168-49-1C14H16ClN3O
(7-Bromo-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone chemical structure, C14H16BrN3O, CAS 459168-51-5
(7-Bromo-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
CAS 459168-51-5C14H16BrN3O
(1H-Indol-2-yl)-(3-methyl-piperazin-1-yl)-methanone chemical structure, C14H17N3O, CAS 459168-50-4
(1H-Indol-2-yl)-(3-methyl-piperazin-1-yl)-methanone
CAS 459168-50-4C14H17N3O
N-[2-(1-Piperazinylcarbonyl)-1H-indol-5-yl]methanesulfonamide chemical structure, C14H18N4O3S, CAS 188790-40-1
N-[2-(1-Piperazinylcarbonyl)-1H-indol-5-yl]methanesulfonamide
CAS 188790-40-1C14H18N4O3S
(6-Bromo-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H16BrN3O, CAS 459169-26-7
(6-Bromo-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 459169-26-7C14H16BrN3O