CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 12 atoms

151 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
151
With full pages
9
Scaffold SMILES

O=c1[nH]cnn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cnn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 151 of 151 chemicals

N-[4-(3-Methyl-5-oxo-4H-1,2,4-triazol-1-yl)phenyl]prop-2-enamide chemical structure, C12H12N4O2, CAS 2305568-37-8
N-[4-(3-Methyl-5-oxo-4H-1,2,4-triazol-1-yl)phenyl]prop-2-enamide
CAS 2305568-37-8C12H12N4O2
Methyl 2-chloro-3-(2-chloro-5-(4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-4-fluorophenyl)propanoate chemical structure, C14H12Cl2F3N3O3, CAS 128621-71-6
Methyl 2-chloro-3-(2-chloro-5-(4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-4-fluorophenyl)propanoate
CAS 128621-71-6C14H12Cl2F3N3O3
N-[4-Chloro-3-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide chemical structure, C11H11ClF2N4O3S, CAS 1254253-56-9
N-[4-Chloro-3-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide
CAS 1254253-56-9C11H11ClF2N4O3S
Ethyl 1-(2-methoxyphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylate chemical structure, C12H13N3O4, CAS 2101221-84-3
Ethyl 1-(2-methoxyphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylate
CAS 2101221-84-3C12H13N3O4
Ethyl 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoate chemical structure, C15H14Cl2F3N3O4, CAS 197512-36-0
Ethyl 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoate
CAS 197512-36-0C15H14Cl2F3N3O4
2-(5-Amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C9H6Cl2F2N4O, CAS 1254253-55-8
2-(5-Amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 1254253-55-8C9H6Cl2F2N4O
5-Bromo-1,2-dihydro-2-phenyl-3H-1,2,4-triazol-3-one chemical structure, C8H6BrN3O, CAS 22354-84-3
5-Bromo-1,2-dihydro-2-phenyl-3H-1,2,4-triazol-3-one
CAS 22354-84-3C8H6BrN3O