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Murcko scaffold

Ring system with 3 rings and 21 atoms

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
40
With full pages
5
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

3-Hydroxy-2-naphthalenecarboxylic acid 2-((3,4-dihydroxyphenyl)methylene)hydrazide chemical structure, C18H14N2O4, CAS 304448-55-3
3-Hydroxy-2-naphthalenecarboxylic acid 2-((3,4-dihydroxyphenyl)methylene)hydrazide
CAS 304448-55-3C18H14N2O4
3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2-hydroxy-3-methoxyphenyl)methylene]hydrazide chemical structure, C19H16N2O4, CAS 80648-85-7
3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2-hydroxy-3-methoxyphenyl)methylene]hydrazide
CAS 80648-85-7C19H16N2O4
N-[(3-Chloro-4-hydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide chemical structure, C18H13ClN2O3
N-[(3-Chloro-4-hydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide
C18H13ClN2O3
3-Hydroxy-2-naphthalenecarboxylic acid 2-[(3-chloro-4-ethoxy-5-methoxyphenyl)methylene]hydrazide chemical structure, C21H19ClN2O4, CAS 870464-25-8
3-Hydroxy-2-naphthalenecarboxylic acid 2-[(3-chloro-4-ethoxy-5-methoxyphenyl)methylene]hydrazide
CAS 870464-25-8C21H19ClN2O4
N-[(3,5-Dibromo-2,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide chemical structure, C18H12Br2N2O4
N-[(3,5-Dibromo-2,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide
C18H12Br2N2O4
3-Hydroxy-N'-[1-(4-methylphenyl)ethylidene]-2-naphthohydrazide chemical structure, C20H18N2O2, CAS 304448-40-6
3-Hydroxy-N'-[1-(4-methylphenyl)ethylidene]-2-naphthohydrazide
CAS 304448-40-6C20H18N2O2
2-[(E)-[(3-Hydroxynaphthalene-2-carbonyl)hydrazinylidene]methyl]benzoic acid chemical structure, C19H14N2O4, CAS 1620053-21-5
2-[(E)-[(3-Hydroxynaphthalene-2-carbonyl)hydrazinylidene]methyl]benzoic acid
CAS 1620053-21-5C19H14N2O4
N'-[1-(4-Aminophenyl)ethylidene]-3-hydroxy-2-naphthohydrazide chemical structure, C19H17N3O2, CAS 300361-53-9
N'-[1-(4-Aminophenyl)ethylidene]-3-hydroxy-2-naphthohydrazide
CAS 300361-53-9C19H17N3O2
3-Hydroxy-N'-[(1E)-2-methyl-1-phenylpropylidene]naphthalene-2-carbohydrazide chemical structure, C21H20N2O2, CAS 304666-05-5
3-Hydroxy-N'-[(1E)-2-methyl-1-phenylpropylidene]naphthalene-2-carbohydrazide
CAS 304666-05-5C21H20N2O2
N'-[4-(Dimethylamino)benzylidene]-3-hydroxy-2-naphthohydrazide chemical structure, C20H19N3O2, CAS 1220339-79-6
N'-[4-(Dimethylamino)benzylidene]-3-hydroxy-2-naphthohydrazide
CAS 1220339-79-6C20H19N3O2
N'-(5-Bromo-2,4-dimethoxybenzylidene)-3-hydroxy-2-naphthohydrazide chemical structure, C20H17BrN2O4, CAS 304479-04-7
N'-(5-Bromo-2,4-dimethoxybenzylidene)-3-hydroxy-2-naphthohydrazide
CAS 304479-04-7C20H17BrN2O4
N'-[4-(Diethylamino)benzylidene]-3-hydroxy-2-naphthohydrazide chemical structure, C22H23N3O2, CAS 312525-42-1
N'-[4-(Diethylamino)benzylidene]-3-hydroxy-2-naphthohydrazide
CAS 312525-42-1C22H23N3O2
3-Hydroxy-N'-(2-methylbenzylidene)-2-naphthohydrazide chemical structure, C19H16N2O2, CAS 91989-47-8
3-Hydroxy-N'-(2-methylbenzylidene)-2-naphthohydrazide
CAS 91989-47-8C19H16N2O2
3-Hydroxy-N'-(2-nitrobenzylidene)-2-naphthohydrazide chemical structure, C18H13N3O4, CAS 1448325-03-8
3-Hydroxy-N'-(2-nitrobenzylidene)-2-naphthohydrazide
CAS 1448325-03-8C18H13N3O4
N'-(2-Chloro-6-fluorobenzylidene)-3-hydroxy-2-naphthohydrazide chemical structure, C18H12ClFN2O2, CAS 358665-39-1
N'-(2-Chloro-6-fluorobenzylidene)-3-hydroxy-2-naphthohydrazide
CAS 358665-39-1C18H12ClFN2O2
N-[(E)-(2-Chlorophenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide chemical structure, C18H13ClN2O2, CAS 91989-50-3
N-[(E)-(2-Chlorophenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide
CAS 91989-50-3C18H13ClN2O2
N-[(E)-(2-Fluorophenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide chemical structure, C18H13FN2O2, CAS 93589-82-3
N-[(E)-(2-Fluorophenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide
CAS 93589-82-3C18H13FN2O2
N'-(4-Ethoxybenzylidene)-3-hydroxy-2-naphthohydrazide chemical structure, C20H18N2O3, CAS 91989-57-0
N'-(4-Ethoxybenzylidene)-3-hydroxy-2-naphthohydrazide
CAS 91989-57-0C20H18N2O3
N'-(4-Fluorobenzylidene)-3-hydroxy-2-naphthohydrazide chemical structure, C18H13FN2O2, CAS 93589-84-5
N'-(4-Fluorobenzylidene)-3-hydroxy-2-naphthohydrazide
CAS 93589-84-5C18H13FN2O2
N'-[1-(3-Aminophenyl)ethylidene]-3-hydroxy-2-naphthohydrazide chemical structure, C19H17N3O2, CAS 304480-33-9
N'-[1-(3-Aminophenyl)ethylidene]-3-hydroxy-2-naphthohydrazide
CAS 304480-33-9C19H17N3O2
N'-[(E)-(2-Fluorophenyl)methylidene]-1-hydroxynaphthalene-2-carbohydrazide chemical structure, C18H13FN2O2, CAS 627061-60-3
N'-[(E)-(2-Fluorophenyl)methylidene]-1-hydroxynaphthalene-2-carbohydrazide
CAS 627061-60-3C18H13FN2O2
N'-Benzylidene-1-hydroxy-2-naphthohydrazide chemical structure, C18H14N2O2, CAS 73190-33-7
N'-Benzylidene-1-hydroxy-2-naphthohydrazide
CAS 73190-33-7C18H14N2O2
N'-[(E)-(2,3-Dimethoxyphenyl)methylidene]-1-hydroxynaphthalene-2-carbohydrazide chemical structure, C20H18N2O4, CAS 627061-53-4
N'-[(E)-(2,3-Dimethoxyphenyl)methylidene]-1-hydroxynaphthalene-2-carbohydrazide
CAS 627061-53-4C20H18N2O4
1-Hydroxy-N'-[(E)-(3-hydroxyphenyl)methylidene]naphthalene-2-carbohydrazide chemical structure, C18H14N2O3, CAS 610266-79-0
1-Hydroxy-N'-[(E)-(3-hydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
CAS 610266-79-0C18H14N2O3