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Murcko scaffold

1-Oxa-4,8-diazaspiro[4.5]decan-3-one scaffold

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
16
With full pages
4
Scaffold SMILES

O=C1COC2(CCNCC2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Oxa-4,8-diazaspiro[4.5]decan-3-one page
Murcko scaffold O=C1COC2(CCNCC2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

2,2,7,7,9,9-Hexamethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C13H24N2O2, CAS 66462-14-4
2,2,7,7,9,9-Hexamethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 66462-14-4C13H24N2O2
1-Oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C7H12N2O2, CAS 746543-82-8
1-Oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 746543-82-8C7H12N2O2
Sulfuric acid--2,2,7,7,9,9-hexamethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one (1/1) chemical structure, C13H26N2O6S, CAS 66462-15-5
Sulfuric acid--2,2,7,7,9,9-hexamethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one (1/1)
CAS 66462-15-5C13H26N2O6S
2,2-Dimethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C9H16N2O2, CAS 52030-29-2
2,2-Dimethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 52030-29-2C9H16N2O2
tert-Butyl 3-oxo-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C12H20N2O4, CAS 1817613-54-9
tert-Butyl 3-oxo-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1817613-54-9C12H20N2O4
2-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C8H14N2O2, CAS 51137-87-2
2-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 51137-87-2C8H14N2O2
2-Ethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C9H16N2O2, CAS 712255-89-5
2-Ethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 712255-89-5C9H16N2O2
2-Ethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrobromide chemical structure, C9H17BrN2O2, CAS 37623-20-4
2-Ethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrobromide
CAS 37623-20-4C9H17BrN2O2
1-Oxa-4,8-diazaspiro[4.5]decan-3-one hydrobromide chemical structure, C7H13BrN2O2, CAS 37048-63-8
1-Oxa-4,8-diazaspiro[4.5]decan-3-one hydrobromide
CAS 37048-63-8C7H13BrN2O2
2-Methyl-1-oxa-4,8-diazaspiro(4.5)decan-3-one hydrobromide chemical structure, C8H15BrN2O2, CAS 50707-79-4
2-Methyl-1-oxa-4,8-diazaspiro(4.5)decan-3-one hydrobromide
CAS 50707-79-4C8H15BrN2O2
4-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrochloride chemical structure, C8H15ClN2O2, CAS 2241139-70-6
4-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrochloride
CAS 2241139-70-6C8H15ClN2O2
4-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C8H14N2O2, CAS 2241138-69-0
4-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 2241138-69-0C8H14N2O2
2,2-Dimethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrochloride chemical structure, C9H17ClN2O2, CAS 2248317-99-7
2,2-Dimethyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrochloride
CAS 2248317-99-7C9H17ClN2O2
2,2-Dimethyl-8-prop-2-enoyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C12H18N2O3, CAS 2361655-84-5
2,2-Dimethyl-8-prop-2-enoyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 2361655-84-5C12H18N2O3
8-(2-Chloropropanoyl)-2-methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one chemical structure, C11H17ClN2O3, CAS 2411201-64-2
8-(2-Chloropropanoyl)-2-methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one
CAS 2411201-64-2C11H17ClN2O3
2-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrochloride chemical structure, C8H15ClN2O2, CAS 37623-08-8
2-Methyl-1-oxa-4,8-diazaspiro[4.5]decan-3-one hydrochloride
CAS 37623-08-8C8H15ClN2O2