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Murcko scaffold

Ring system with 3 rings and 19 atoms

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
29
With full pages
5
Scaffold SMILES

S=C(c1ccc(-c2ccccc2)o1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(c1ccc(-c2ccccc2)o1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

3-(4-(5-(2,5-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H17Cl2N3OS, CAS 332862-27-8
3-(4-(5-(2,5-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 332862-27-8C18H17Cl2N3OS
3-(4-(5-(4-Chlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18ClN3OS, CAS 370574-31-5
3-(4-(5-(4-Chlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 370574-31-5C18H18ClN3OS
1-[4-[5-(4-Methylphenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone chemical structure, C18H20N2O2S, CAS 394238-11-0
1-[4-[5-(4-Methylphenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone
CAS 394238-11-0C18H20N2O2S
(4-Methylpiperazin-1-yl)-[5-(3-nitrophenyl)furan-2-yl]methanethione chemical structure, C16H17N3O3S, CAS 714927-30-7
(4-Methylpiperazin-1-yl)-[5-(3-nitrophenyl)furan-2-yl]methanethione
CAS 714927-30-7C16H17N3O3S
1-[4-[5-(4-Fluorophenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone chemical structure, C17H17FN2O2S, CAS 840497-99-6
1-[4-[5-(4-Fluorophenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone
CAS 840497-99-6C17H17FN2O2S
1-(4-(5-(2,5-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H16Cl2N2O2S, CAS 370573-57-2
1-(4-(5-(2,5-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 370573-57-2C17H16Cl2N2O2S
1-[4-[5-(2,3-Dichlorophenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone chemical structure, C17H16Cl2N2O2S, CAS 433259-92-8
1-[4-[5-(2,3-Dichlorophenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone
CAS 433259-92-8C17H16Cl2N2O2S
1-[4-[5-(3-Nitrophenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone chemical structure, C17H17N3O4S, CAS 394238-15-4
1-[4-[5-(3-Nitrophenyl)furan-2-carbothioyl]piperazin-1-yl]ethanone
CAS 394238-15-4C17H17N3O4S
1-(4-(5-(3,4-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H16Cl2N2O2S, CAS 394238-21-2
1-(4-(5-(3,4-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 394238-21-2C17H16Cl2N2O2S
1-(4-(5-(2,4-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H16Cl2N2O2S, CAS 370573-59-4
1-(4-(5-(2,4-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 370573-59-4C17H16Cl2N2O2S
1-(4-(5-(4-Chloro-2-nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H16ClN3O4S, CAS 394238-26-7
1-(4-(5-(4-Chloro-2-nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 394238-26-7C17H16ClN3O4S
1-(4-(5-(2-Nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H17N3O4S, CAS 370575-98-7
1-(4-(5-(2-Nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 370575-98-7C17H17N3O4S
1-(4-(5-(4-Bromophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H17BrN2O2S, CAS 370572-69-3
1-(4-(5-(4-Bromophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 370572-69-3C17H17BrN2O2S
1-(4-(5-(2-Chloro-4-nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone chemical structure, C17H16ClN3O4S, CAS 714247-81-1
1-(4-(5-(2-Chloro-4-nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)ethanone
CAS 714247-81-1C17H16ClN3O4S
3-[4-[5-(3-Nitrophenyl)furan-2-carbothioyl]piperazin-1-yl]propanenitrile chemical structure, C18H18N4O3S, CAS 332862-26-7
3-[4-[5-(3-Nitrophenyl)furan-2-carbothioyl]piperazin-1-yl]propanenitrile
CAS 332862-26-7C18H18N4O3S
3-(4-(5-(2-Nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18N4O3S, CAS 332862-25-6
3-(4-(5-(2-Nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 332862-25-6C18H18N4O3S
3-(4-(5-(4-Nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18N4O3S, CAS 459194-23-1
3-(4-(5-(4-Nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 459194-23-1C18H18N4O3S
3-(4-(5-(2-Chloro-4-nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H17ClN4O3S, CAS 579443-34-8
3-(4-(5-(2-Chloro-4-nitrophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 579443-34-8C18H17ClN4O3S
3-(4-(5-(2-Chlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18ClN3OS, CAS 332862-23-4
3-(4-(5-(2-Chlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 332862-23-4C18H18ClN3OS
3-(4-(5-(2,3-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H17Cl2N3OS, CAS 332862-29-0
3-(4-(5-(2,3-Dichlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 332862-29-0C18H17Cl2N3OS
3-(4-(5-(3-Chlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18ClN3OS, CAS 459194-15-1
3-(4-(5-(3-Chlorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 459194-15-1C18H18ClN3OS
3-(4-(5-(4-Bromophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18BrN3OS, CAS 332862-24-5
3-(4-(5-(4-Bromophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 332862-24-5C18H18BrN3OS
[5-(2,5-Dichlorophenyl)furan-2-yl]-(4-methylpiperazin-1-yl)methanethione chemical structure, C16H16Cl2N2OS, CAS 585552-20-1
[5-(2,5-Dichlorophenyl)furan-2-yl]-(4-methylpiperazin-1-yl)methanethione
CAS 585552-20-1C16H16Cl2N2OS
3-(4-(5-(4-Fluorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile chemical structure, C18H18FN3OS, CAS 578749-13-0
3-(4-(5-(4-Fluorophenyl)furan-2-carbonothioyl)piperazin-1-yl)propanenitrile
CAS 578749-13-0C18H18FN3OS