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Murcko scaffold

3-Phenyl-5-(phenylmethyl)-2-thioxo-4-imidazolidinone scaffold

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
4
Scaffold SMILES

O=C1C(Cc2ccccc2)NC(=S)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-5-(phenylmethyl)-2-thioxo-4-imidazolidinone page
Murcko scaffold O=C1C(Cc2ccccc2)NC(=S)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Tyrosine phenylthiohydantoin chemical structure, C16H14N2O2S, CAS 4332-95-0
Tyrosine phenylthiohydantoin
CAS 4332-95-0C16H14N2O2S
(5S)-5-Benzyl-3-phenyl-2-sulfanylideneimidazolidin-4-one chemical structure, C16H14N2OS, CAS 29588-07-6
(5S)-5-Benzyl-3-phenyl-2-sulfanylideneimidazolidin-4-one
CAS 29588-07-6C16H14N2OS
3-Phenyl-5-(phenylmethyl)-2-thioxo-4-imidazolidinone chemical structure, C16H14N2OS, CAS 4332-97-2
3-Phenyl-5-(phenylmethyl)-2-thioxo-4-imidazolidinone
CAS 4332-97-2C16H14N2OS
4-Imidazolidinone, 5-((4-hydroxyphenyl)methyl)-3-phenyl-2-thioxo- chemical structure, C16H14N2O2S, CAS 29588-08-7
4-Imidazolidinone, 5-((4-hydroxyphenyl)methyl)-3-phenyl-2-thioxo-
CAS 29588-08-7C16H14N2O2S
5-Benzyl-3-(4-methylphenyl)-2-sulfanylideneimidazolidin-4-one chemical structure, C17H16N2OS, CAS 1008201-48-6
5-Benzyl-3-(4-methylphenyl)-2-sulfanylideneimidazolidin-4-one
CAS 1008201-48-6C17H16N2OS
Phenylthiohydantoin-3,4-dihydroxyphenylalanine chemical structure, C16H14N2O3S, CAS 132828-63-8
Phenylthiohydantoin-3,4-dihydroxyphenylalanine
CAS 132828-63-8C16H14N2O3S
5-(4-Hydroxy-3-nitrobenzyl)-3-phenyl-2-thiohydantoin chemical structure, C16H13N3O4S, CAS 105956-89-6
5-(4-Hydroxy-3-nitrobenzyl)-3-phenyl-2-thiohydantoin
CAS 105956-89-6C16H13N3O4S
5-[(2-Hydroxyphenyl)methyl]-3-phenyl-2-sulfanylideneimidazolidin-4-one chemical structure, C16H14N2O2S, CAS 329350-54-1
5-[(2-Hydroxyphenyl)methyl]-3-phenyl-2-sulfanylideneimidazolidin-4-one
CAS 329350-54-1C16H14N2O2S
(5S)-5-Benzyl-3-(2-methylphenyl)-2-sulfanylideneimidazolidin-4-one chemical structure, C17H16N2OS, CAS 62289-46-7
(5S)-5-Benzyl-3-(2-methylphenyl)-2-sulfanylideneimidazolidin-4-one
CAS 62289-46-7C17H16N2OS
(5S)-5-Benzyl-3-(4-bromophenyl)-2-sulfanylideneimidazolidin-4-one chemical structure, C16H13BrN2OS, CAS 61357-84-4
(5S)-5-Benzyl-3-(4-bromophenyl)-2-sulfanylideneimidazolidin-4-one
CAS 61357-84-4C16H13BrN2OS