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Murcko scaffold

Ring system with 3 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
8
With full pages
6
Scaffold SMILES

O=C1COc2ccc(C(=O)COC(=O)c3ccccc3)cc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1COc2ccc(C(=O)COC(=O)c3ccccc3)cc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2,4,5-trimethoxybenzoate chemical structure, C20H19NO8, CAS 453515-29-2
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2,4,5-trimethoxybenzoate
CAS 453515-29-2C20H19NO8
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 4-methoxy-3-nitrobenzoate chemical structure, C18H14N2O8, CAS 380483-00-1
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 4-methoxy-3-nitrobenzoate
CAS 380483-00-1C18H14N2O8
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-chlorobenzoate chemical structure, C17H12ClNO5, CAS 502970-20-9
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-chlorobenzoate
CAS 502970-20-9C17H12ClNO5
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-chloro-4-fluorobenzoate chemical structure, C17H11ClFNO5, CAS 454687-30-0
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-chloro-4-fluorobenzoate
CAS 454687-30-0C17H11ClFNO5
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 3-methylbenzoate chemical structure, C18H15NO5, CAS 502986-94-9
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 3-methylbenzoate
CAS 502986-94-9C18H15NO5
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-formylbenzoate chemical structure, C18H13NO6, CAS 733791-26-9
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 2-formylbenzoate
CAS 733791-26-9C18H13NO6
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 3,4-dimethoxybenzoate chemical structure, C19H17NO7, CAS 454231-07-3
[2-Oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] 3,4-dimethoxybenzoate
CAS 454231-07-3C19H17NO7
[2-Oxidanylidene-2-(3-oxidanylidene-4H-1,4-benzoxazin-6-yl)ethyl] 4-(2-cyanoethanoylamino)benzoate chemical structure, C20H15N3O6, CAS 1090825-30-1
[2-Oxidanylidene-2-(3-oxidanylidene-4H-1,4-benzoxazin-6-yl)ethyl] 4-(2-cyanoethanoylamino)benzoate
CAS 1090825-30-1C20H15N3O6