Murcko scaffold
8-Thia-2-azaspiro[4.5]decane 8,8-dioxide scaffold
25 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 25
- With full pages
- 3
Scaffold SMILES
O=S1(=O)CCC2(CCNC2)CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 25 of 25 chemicals
![Ethyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylate chemical structure, C11H19NO4S, CAS 1272655-77-2](/s/SZBPDNCZMHSPEG-UHFFFAOYSA-N.svg)
Ethyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylate
CAS 1272655-77-2C11H19NO4S
![8-Thia-2-azaspiro[4.5]decane 8,8-dioxide chemical structure, C8H15NO2S, CAS 1250496-39-9](/s/IJLJEBISGITNGH-UHFFFAOYSA-N.svg)
8-Thia-2-azaspiro[4.5]decane 8,8-dioxide
CAS 1250496-39-9C8H15NO2S
![8,8-Dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C9H15NO4S, CAS 1342163-30-7](/s/GZJKRBAQHOEEME-UHFFFAOYSA-N.svg)
8,8-Dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid
CAS 1342163-30-7C9H15NO4S
![8,8-Dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C9H15NO4S, CAS 1779730-04-9](/s/PLTUYOUDHUKRLS-UHFFFAOYSA-N.svg)
8,8-Dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid
CAS 1779730-04-9C9H15NO4S
![Methyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylate chemical structure, C10H17NO4S, CAS 1779354-16-3](/s/LQBSJYAWRSBXPV-UHFFFAOYSA-N.svg)
Methyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylate
CAS 1779354-16-3C10H17NO4S
![Methyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylate chemical structure, C10H17NO4S, CAS 1600466-55-4](/s/WALKXNITQHWVNC-UHFFFAOYSA-N.svg)
Methyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylate
CAS 1600466-55-4C10H17NO4S
![Ethyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylate chemical structure, C11H19NO4S, CAS 1772885-62-7](/s/DVJIZVPBXNRINQ-UHFFFAOYSA-N.svg)
Ethyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylate
CAS 1772885-62-7C11H19NO4S
![8-Thia-2-azaspiro[4.5]decane 8,8-dioxide hydrochloride chemical structure, C8H16ClNO2S, CAS 2248344-54-7](/s/GRLWAZHHSVGLBN-UHFFFAOYSA-N.svg)
8-Thia-2-azaspiro[4.5]decane 8,8-dioxide hydrochloride
CAS 2248344-54-7C8H16ClNO2S
![2-[(tert-Butoxy)carbonyl]-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C14H23NO6S, CAS 2174007-74-8](/s/MEPUTCPBJLZGRH-UHFFFAOYSA-N.svg)
2-[(tert-Butoxy)carbonyl]-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid
CAS 2174007-74-8C14H23NO6S
![tert-Butyl N-{8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decan-4-yl}carbamate chemical structure, C13H24N2O4S, CAS 2225136-09-2](/s/KLIJNPDDNAMPCL-UHFFFAOYSA-N.svg)
tert-Butyl N-{8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decan-4-yl}carbamate
CAS 2225136-09-2C13H24N2O4S
![tert-Butyl 4-amino-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-2-carboxylate chemical structure, C13H24N2O4S, CAS 2225144-87-4](/s/QGLJPYRZXUVWTI-UHFFFAOYSA-N.svg)
tert-Butyl 4-amino-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-2-carboxylate
CAS 2225144-87-4C13H24N2O4S
![8,8-Dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid hydrochloride chemical structure, C9H16ClNO4S, CAS 2287260-36-8](/s/RLWGZDRXIZMJMV-UHFFFAOYSA-N.svg)
8,8-Dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid hydrochloride
CAS 2287260-36-8C9H16ClNO4S
![2-[(tert-Butoxy)carbonyl]-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C14H23NO6S, CAS 2305253-38-5](/s/FDDBJPPBIQFKPM-UHFFFAOYSA-N.svg)
2-[(tert-Butoxy)carbonyl]-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid
CAS 2305253-38-5C14H23NO6S
![Methyl8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylatehydrochloride chemical structure, C10H18ClNO4S, CAS 2309444-93-5](/s/WURQWFKYFDQAAC-UHFFFAOYSA-N.svg)
Methyl8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylatehydrochloride
CAS 2309444-93-5C10H18ClNO4S
![2-(Prop-2-enoyl)-8lambda6-thia-2-azaspiro[4.5]decane-8,8-dione chemical structure, C11H17NO3S, CAS 2361657-58-9](/s/CDDHVVWRGDLJSD-UHFFFAOYSA-N.svg)
2-(Prop-2-enoyl)-8lambda6-thia-2-azaspiro[4.5]decane-8,8-dione
CAS 2361657-58-9C11H17NO3S
![4,4-Difluoro-8lambda6-thia-2-azaspiro[4.5]decane-8,8-dione chemical structure, C8H13F2NO2S, CAS 2138389-48-5](/s/LTUWZNQOEMMQAI-UHFFFAOYSA-N.svg)
4,4-Difluoro-8lambda6-thia-2-azaspiro[4.5]decane-8,8-dione
CAS 2138389-48-5C8H13F2NO2S
![tert-Butyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylate chemical structure, C13H23NO4S, CAS 2639407-06-8](/s/CUHVRVDUZBDRAG-UHFFFAOYSA-N.svg)
tert-Butyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylate
CAS 2639407-06-8C13H23NO4S
![tert-Butyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylate chemical structure, C13H23NO4S, CAS 2639403-12-4](/s/VAVWYRHNVGYJHO-UHFFFAOYSA-N.svg)
tert-Butyl 8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylate
CAS 2639403-12-4C13H23NO4S
![2-Acetyl-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C11H17NO5S, CAS 2680810-80-2](/s/FHFVPPBKDJORHE-UHFFFAOYSA-N.svg)
2-Acetyl-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid
CAS 2680810-80-2C11H17NO5S
![2-Acetyl-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C11H17NO5S, CAS 2680586-12-1](/s/GNZUIHLUXLSOAY-UHFFFAOYSA-N.svg)
2-Acetyl-8,8-dioxo-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid
CAS 2680586-12-1C11H17NO5S
![8,8-Dioxo-2-(2,2,2-trifluoroacetyl)-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid chemical structure, C11H14F3NO5S, CAS 2680900-01-8](/s/GCVJVYAZFHPFEP-UHFFFAOYSA-N.svg)
8,8-Dioxo-2-(2,2,2-trifluoroacetyl)-8lambda6-thia-2-azaspiro[4.5]decane-4-carboxylic acid
CAS 2680900-01-8C11H14F3NO5S
![8,8-Dioxo-2-(2,2,2-trifluoroacetyl)-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C11H14F3NO5S, CAS 2680612-69-3](/s/NLHREHXHLDXJDO-UHFFFAOYSA-N.svg)
8,8-Dioxo-2-(2,2,2-trifluoroacetyl)-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid
CAS 2680612-69-3C11H14F3NO5S
![4-Amino-8lambda6-thia-2-azaspiro[4.5]decane-8,8-dione chemical structure, C8H16N2O2S, CAS 2138192-59-1](/s/NTWZKEKMPODGHL-UHFFFAOYSA-N.svg)
4-Amino-8lambda6-thia-2-azaspiro[4.5]decane-8,8-dione
CAS 2138192-59-1C8H16N2O2S
![8,8-Dioxo-2-[(prop-2-en-1-yloxy)carbonyl]-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C13H19NO6S, CAS 2763906-31-4](/s/WWRXHXNMJAZIDC-UHFFFAOYSA-N.svg)
8,8-Dioxo-2-[(prop-2-en-1-yloxy)carbonyl]-8lambda6-thia-2-azaspiro[4.5]decane-3-carboxylic acid
CAS 2763906-31-4C13H19NO6S
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Same ring framework with different atoms or bond orders
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