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Murcko scaffold

Ring system with 3 rings and 21 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
5
With full pages
4
Scaffold SMILES

O=c1[nH]c(SCCOc2ccccc2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(SCCOc2ccccc2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

RefChem:380567 chemical structure, C17H16N2O3S, CAS 5487-23-0
RefChem:380567
CAS 5487-23-0C17H16N2O3S
2-[2-(4-Ethoxyphenoxy)ethylsulfanyl]-1H-quinazolin-4-one chemical structure, C18H18N2O3S, CAS 326903-85-9
2-[2-(4-Ethoxyphenoxy)ethylsulfanyl]-1H-quinazolin-4-one
CAS 326903-85-9C18H18N2O3S
2-[[2-[4-(1,1-Dimethylethyl)phenoxy]ethyl]thio]-4(3H)-quinazolinone chemical structure, C20H22N2O2S, CAS 328977-87-3
2-[[2-[4-(1,1-Dimethylethyl)phenoxy]ethyl]thio]-4(3H)-quinazolinone
CAS 328977-87-3C20H22N2O2S
2-[2-(3-Methoxyphenoxy)ethylsulfanyl]-1H-quinazolin-4-one chemical structure, C17H16N2O3S, CAS 330955-60-7
2-[2-(3-Methoxyphenoxy)ethylsulfanyl]-1H-quinazolin-4-one
CAS 330955-60-7C17H16N2O3S
RefChem:380568 chemical structure, C17H16N2O3S, CAS 5492-41-1
RefChem:380568
CAS 5492-41-1C17H16N2O3S