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Murcko scaffold

Ring system with 3 rings and 20 atoms

54 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
54
With full pages
2
Scaffold SMILES

c1ccc(CN2CCC(Nc3ccccn3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CN2CCC(Nc3ccccn3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

Rbi 257 chemical structure, C21H28IN3O, CAS 194038-94-3
Rbi 257
CAS 194038-94-3C21H28IN3O
RefChem:192837 chemical structure, C20H27N3O, CAS 179556-82-2
RefChem:192837
CAS 179556-82-2C20H27N3O
N-(1-Benzylpiperidin-4-yl)-3-nitropyridin-2-amine chemical structure, C17H20N4O2, CAS 185058-54-2
N-(1-Benzylpiperidin-4-yl)-3-nitropyridin-2-amine
CAS 185058-54-2C17H20N4O2
1-Benzyl-4-(N-methyl-N-(3-acetyl-2-pyridyl)amino)piperidine chemical structure, C20H25N3O, CAS 179556-60-6
1-Benzyl-4-(N-methyl-N-(3-acetyl-2-pyridyl)amino)piperidine
CAS 179556-60-6C20H25N3O
N-(1-Benzylpiperidin-4-yl)-3-ethyl-N-propylpyridin-2-amine chemical structure, C22H31N3, CAS 179556-69-5
N-(1-Benzylpiperidin-4-yl)-3-ethyl-N-propylpyridin-2-amine
CAS 179556-69-5C22H31N3
2-[(1-Benzylpiperidin-4-yl)-ethylamino]pyridine-3-carbonitrile chemical structure, C20H24N4, CAS 179556-63-9
2-[(1-Benzylpiperidin-4-yl)-ethylamino]pyridine-3-carbonitrile
CAS 179556-63-9C20H24N4
[2-[(1-Benzylpiperidin-4-yl)-ethylamino]-3-pyridinyl]methanol chemical structure, C20H27N3O, CAS 179556-56-0
[2-[(1-Benzylpiperidin-4-yl)-ethylamino]-3-pyridinyl]methanol
CAS 179556-56-0C20H27N3O
1-Benzyl-4-(N-methyl-N-(3-hydroxymethyl-2-pyridyl)amino)piperidine chemical structure, C19H25N3O, CAS 179556-51-5
1-Benzyl-4-(N-methyl-N-(3-hydroxymethyl-2-pyridyl)amino)piperidine
CAS 179556-51-5C19H25N3O
1-Benzyl-4-[N-methyl-N-(3-amino-2-pyridinyl)amino]piperidine chemical structure, C18H24N4, CAS 163276-82-2
1-Benzyl-4-[N-methyl-N-(3-amino-2-pyridinyl)amino]piperidine
CAS 163276-82-2C18H24N4
1-Benzyl-4-[N-ethyl-N-(3-amino-2-pyridinyl)amino]piperidine chemical structure, C19H26N4, CAS 179558-09-9
1-Benzyl-4-[N-ethyl-N-(3-amino-2-pyridinyl)amino]piperidine
CAS 179558-09-9C19H26N4
1-Benzyl-4-[N-methyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine chemical structure, C22H29N3, CAS 179556-29-7
1-Benzyl-4-[N-methyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine
CAS 179556-29-7C22H29N3
1-Benzyl-4-[N-ethyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine chemical structure, C23H31N3, CAS 179556-30-0
1-Benzyl-4-[N-ethyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine
CAS 179556-30-0C23H31N3
2-[(1-Benzylpiperidin-4-yl)-propylamino]pyridine-3-carbonitrile chemical structure, C21H26N4, CAS 179556-67-3
2-[(1-Benzylpiperidin-4-yl)-propylamino]pyridine-3-carbonitrile
CAS 179556-67-3C21H26N4
N-(1-Benzylpiperidin-4-yl)-N-ethyl-3-(methoxymethyl)pyridin-2-amine chemical structure, C21H29N3O, CAS 179556-57-1
N-(1-Benzylpiperidin-4-yl)-N-ethyl-3-(methoxymethyl)pyridin-2-amine
CAS 179556-57-1C21H29N3O
1-Benzyl-4-[N-ethyl-N-(3-(isopropylamino)-2-pyridinyl)amino]piperidine chemical structure, C22H32N4, CAS 179557-43-8
1-Benzyl-4-[N-ethyl-N-(3-(isopropylamino)-2-pyridinyl)amino]piperidine
CAS 179557-43-8C22H32N4
1-Benzyl-4-(N-methyl-N-(3-ethyl-2-pyridyl)amino)piperidine chemical structure, C20H27N3, CAS 179556-61-7
1-Benzyl-4-(N-methyl-N-(3-ethyl-2-pyridyl)amino)piperidine
CAS 179556-61-7C20H27N3
N-(1-Benzylpiperidin-4-yl)-N,3-diethylpyridin-2-amine chemical structure, C21H29N3, CAS 179556-65-1
N-(1-Benzylpiperidin-4-yl)-N,3-diethylpyridin-2-amine
CAS 179556-65-1C21H29N3
1-Benzyl-4-(N-methyl-N-(3-cyano-2-pyridyl)amino)piperidine chemical structure, C19H22N4, CAS 179556-59-3
1-Benzyl-4-(N-methyl-N-(3-cyano-2-pyridyl)amino)piperidine
CAS 179556-59-3C19H22N4
1-Benzyl-4-(N-methyl-N-(3-methoxycarbonyl-2-pyridyl)amino)piperidine chemical structure, C20H25N3O2, CAS 179556-50-4
1-Benzyl-4-(N-methyl-N-(3-methoxycarbonyl-2-pyridyl)amino)piperidine
CAS 179556-50-4C20H25N3O2
1-Benzyl-4-[N-ethyl-N-(3-(formyl)-2-pyridinyl)amino]piperidine chemical structure, C20H25N3O, CAS 179556-24-2
1-Benzyl-4-[N-ethyl-N-(3-(formyl)-2-pyridinyl)amino]piperidine
CAS 179556-24-2C20H25N3O
2-N-(1-Benzylpiperidin-4-yl)-2-N-propan-2-ylpyridine-2,3-diamine chemical structure, C20H28N4, CAS 179558-62-4
2-N-(1-Benzylpiperidin-4-yl)-2-N-propan-2-ylpyridine-2,3-diamine
CAS 179558-62-4C20H28N4
1-[2-[(1-Benzylpiperidin-4-yl)-propylamino]-3-pyridinyl]ethanone chemical structure, C22H29N3O, CAS 179556-68-4
1-[2-[(1-Benzylpiperidin-4-yl)-propylamino]-3-pyridinyl]ethanone
CAS 179556-68-4C22H29N3O
1-[2-[(1-Benzylpiperidin-4-yl)-ethylamino]-3-pyridinyl]ethanone chemical structure, C21H27N3O, CAS 179556-64-0
1-[2-[(1-Benzylpiperidin-4-yl)-ethylamino]-3-pyridinyl]ethanone
CAS 179556-64-0C21H27N3O
Methyl 2-[(1-benzylpiperidin-4-yl)-ethylamino]pyridine-3-carboxylate chemical structure, C21H27N3O2, CAS 179556-55-9
Methyl 2-[(1-benzylpiperidin-4-yl)-ethylamino]pyridine-3-carboxylate
CAS 179556-55-9C21H27N3O2