Murcko scaffold
6,9-Dioxa-2-azaspiro[4.5]decane scaffold
33 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 33
- With full pages
- 3
Scaffold SMILES
C1CC2(CN1)COCCO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 33 of 33 chemicals
6,9-Dioxa-2-azaspiro[4.5]decane
CAS 1184197-90-7C7H13NO2
6,9-Dioxa-2-azaspiro[4.5]decane hydrochloride
CAS 2138024-11-8C7H14ClNO2
tert-Butyl 7-(iodomethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2172168-91-9C13H22INO4
6,9-Dioxa-2-azaspiro(4.5)decane-7-carboxylic acid hydrochloride
CAS 2490374-70-2C8H14ClNO4
6,9-Dioxa-2-azaspiro[4.5]decane-7-carboxylic acid
CAS 2490374-69-9C8H13NO4
2-[(tert-Butoxy)carbonyl]-6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylicacid
CAS 2470437-58-0C13H21NO6
Methyl6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylatehydrochloride
CAS 2490418-71-6C9H16ClNO4
Methyl 6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylate
CAS 2490403-95-5C9H15NO4
6,9-Dioxa-2-azaspiro[4.5]decan-7-ylmethanol, hydrochloride
CAS 2567504-44-1C8H16ClNO3
{6,9-Dioxa-2-azaspiro[4.5]decan-7-yl}methanol
CAS 2567497-85-0C8H15NO3
2-{2-[(tert-Butoxy)carbonyl]-6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetic acid
CAS 2172200-30-3C14H23NO6
tert-Butyl 7-(aminomethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate hydrochloride
CAS 2639411-71-3C13H25ClN2O4
tert-Butyl 7-(aminomethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2172139-98-7C13H24N2O4
tert-Butyl 7-(sulfamoylmethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2172588-38-2C13H24N2O6S
tert-Butyl 7-(hydroxymethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2172130-76-4C13H23NO5
tert-Butyl 7-(bromomethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2171923-34-3C13H22BrNO4
tert-Butyl 7-[(chlorosulfonyl)methyl]-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2171913-63-4C13H22ClNO6S
tert-Butyl 7-(azidomethyl)-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2172500-46-6C13H22N4O4
tert-Butyl 7-[(fluorosulfonyl)methyl]-6,9-dioxa-2-azaspiro[4.5]decane-2-carboxylate
CAS 2172459-98-0C13H22FNO6S
Ethyl 6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylate
CAS 2580220-03-5C10H17NO4
tert-Butyl 6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylate
CAS 2639445-24-0C12H21NO4
tert-Butyl 2-{6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetate
CAS 2639419-39-7C13H23NO4
Methyl 2-{6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetate
CAS 2639461-08-6C10H17NO4
2-{6,9-Dioxa-2-azaspiro[4.5]decan-7-yl}acetic acid
CAS 2639413-52-6C9H15NO4
- Ethyl 2-{6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetate2639419-66-0C11H19NO4
- 2-{2-[(Prop-2-en-1-yloxy)carbonyl]-6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetic acid2680871-81-0C13H19NO6
- 1-{6,9-Dioxa-2-azaspiro[4.5]decan-7-yl}methanamine2680701-47-5C8H16N2O2
- 2-Acetyl-6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylic acid2680705-59-1C10H15NO5
- 2-[(Prop-2-en-1-yloxy)carbonyl]-6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylic acid2680749-58-8C12H17NO6
- 2-{2-Acetyl-6,9-dioxa-2-azaspiro[4.5]decan-7-yl}acetic acid2680849-74-3C11H17NO5
- 7-(Iodomethyl)-6,9-dioxa-2-azaspiro[4.5]decane2680846-80-2C8H14INO2
- 2-(2,2,2-Trifluoroacetyl)-6,9-dioxa-2-azaspiro[4.5]decane-7-carboxylic acid2680658-65-3C10H12F3NO5
- 2-[2-(2,2,2-Trifluoroacetyl)-6,9-dioxa-2-azaspiro[4.5]decan-7-yl]acetic acid2680904-82-7C11H14F3NO5