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Murcko scaffold

Ring system with 4 rings and 24 atoms

99 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
99
With full pages
2
Scaffold SMILES

O=C(NCc1c[nH]nn1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1c[nH]nn1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 99 chemicals

2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylpropanoic acid chemical structure, C24H25N5O5, CAS 2172129-42-7
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylpropanoic acid
CAS 2172129-42-7C24H25N5O5
(2R)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-4-hydroxybutanoic acid chemical structure, C24H25N5O6, CAS 2171152-17-1
(2R)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-4-hydroxybutanoic acid
CAS 2171152-17-1C24H25N5O6
2-{[2-(2-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)ethyl]sulfanyl}acetic acid chemical structure, C24H25N5O5S, CAS 2172205-41-1
2-{[2-(2-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)ethyl]sulfanyl}acetic acid
CAS 2172205-41-1C24H25N5O5S
(2R)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid chemical structure, C23H23N5O5, CAS 2171189-26-5
(2R)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid
CAS 2171189-26-5C23H23N5O5
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-hydroxy-2-methylpropanoic acid chemical structure, C24H25N5O6, CAS 2172272-70-5
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-hydroxy-2-methylpropanoic acid
CAS 2172272-70-5C24H25N5O6
2-[2-(2-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)ethoxy]acetic acid chemical structure, C24H25N5O6, CAS 2172441-30-2
2-[2-(2-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)ethoxy]acetic acid
CAS 2172441-30-2C24H25N5O6
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylbutanoic acid chemical structure, C25H27N5O5, CAS 2649062-53-1
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylbutanoic acid
CAS 2649062-53-1C25H27N5O5
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)butanoic acid chemical structure, C24H25N5O5, CAS 2171865-89-5
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)butanoic acid
CAS 2171865-89-5C24H25N5O5
3-(N-Ethyl-2-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid chemical structure, C25H27N5O5, CAS 2172439-31-3
3-(N-Ethyl-2-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid
CAS 2172439-31-3C25H27N5O5
(2S)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)propanoic acid chemical structure, C24H25N5O5, CAS 2171267-12-0
(2S)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)propanoic acid
CAS 2171267-12-0C24H25N5O5
2-[(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)oxy]propanoic acid chemical structure, C23H23N5O6, CAS 2172152-67-7
2-[(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)oxy]propanoic acid
CAS 2172152-67-7C23H23N5O6
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)acetic acid chemical structure, C23H23N5O5, CAS 2171838-12-1
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)acetic acid
CAS 2171838-12-1C23H23N5O5
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)but-2-ynoic acid chemical structure, C24H21N5O5, CAS 2171870-66-7
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)but-2-ynoic acid
CAS 2171870-66-7C24H21N5O5
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)pent-4-enoic acid chemical structure, C25H25N5O5, CAS 2171648-87-4
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)pent-4-enoic acid
CAS 2171648-87-4C25H25N5O5
(3R)-3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)pentanoic acid chemical structure, C25H27N5O5, CAS 2171181-42-1
(3R)-3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)pentanoic acid
CAS 2171181-42-1C25H27N5O5
4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazole-5-carboxylic acid chemical structure, C19H16N4O4, CAS 2193061-11-7
4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazole-5-carboxylic acid
CAS 2193061-11-7C19H16N4O4
2-[4-({[(tert-Butoxy)carbonyl]amino}methyl)-1-methyl-1H-1,2,3-triazol-5-yl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid chemical structure, C26H29N5O6, CAS 2193065-29-9
2-[4-({[(tert-Butoxy)carbonyl]amino}methyl)-1-methyl-1H-1,2,3-triazol-5-yl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid
CAS 2193065-29-9C26H29N5O6
(3R)-3-(4-Bromo-1-methyl-1H-1,2,3-triazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H19BrN4O4, CAS 1843423-95-9
(3R)-3-(4-Bromo-1-methyl-1H-1,2,3-triazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1843423-95-9C21H19BrN4O4
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-3-methylbutanoic acid chemical structure, C25H27N5O5, CAS 2171950-85-7
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-3-methylbutanoic acid
CAS 2171950-85-7C25H27N5O5
2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-2-methylpropanoic acid chemical structure, C22H22N4O4, CAS 2757922-79-3
2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-2-methylpropanoic acid
CAS 2757922-79-3C22H22N4O4
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-(prop-2-yn-1-yl)acetamido)acetic acid chemical structure, C25H23N5O5, CAS 2171988-10-4
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-(prop-2-yn-1-yl)acetamido)acetic acid
CAS 2171988-10-4C25H23N5O5
5-{[Ethyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]methyl}-1H-1,2,3-triazole-4-carboxylic acid chemical structure, C21H20N4O4, CAS 2137607-22-6
5-{[Ethyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]methyl}-1H-1,2,3-triazole-4-carboxylic acid
CAS 2137607-22-6C21H20N4O4
2-[(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)oxy]acetic acid chemical structure, C23H23N5O6, CAS 2172324-32-0
2-[(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)oxy]acetic acid
CAS 2172324-32-0C23H23N5O6
(2S)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-4-hydroxybutanoic acid chemical structure, C24H25N5O6, CAS 2171185-29-6
(2S)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-4-hydroxybutanoic acid
CAS 2171185-29-6C24H25N5O6