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Murcko scaffold

Ring system with 3 rings and 18 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
8
With full pages
4
Scaffold SMILES

c1ccc(Cc2nc(-c3ccncc3)no2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2nc(-c3ccncc3)no2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4-[5-[(4-Methoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C15H13N3O2, CAS 438622-95-8
4-[5-[(4-Methoxyphenyl)methyl]-1,2,4-oxadiazol-3-yl]pyridine
CAS 438622-95-8C15H13N3O2
4-[5-(2-Methoxybenzyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C15H13N3O2, CAS 667880-06-0
4-[5-(2-Methoxybenzyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 667880-06-0C15H13N3O2
4-[5-(4-Chlorobenzyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C14H10ClN3O, CAS 442555-70-6
4-[5-(4-Chlorobenzyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 442555-70-6C14H10ClN3O
4-[5-(4-Methylbenzyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C15H13N3O, CAS 694452-01-2
4-[5-(4-Methylbenzyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 694452-01-2C15H13N3O
2-((3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)aniline chemical structure, C14H12N4O, CAS 1490865-26-3
2-((3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)aniline
CAS 1490865-26-3C14H12N4O
2-Ethoxy-N-(2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)acetamide chemical structure, C18H18N4O3, CAS 1797597-96-6
2-Ethoxy-N-(2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)acetamide
CAS 1797597-96-6C18H18N4O3
Ethyl (2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)carbamate chemical structure, C17H16N4O3, CAS 1797602-92-6
Ethyl (2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)carbamate
CAS 1797602-92-6C17H16N4O3
1-Isopropyl-3-(2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)urea chemical structure, C18H19N5O2, CAS 1796969-95-3
1-Isopropyl-3-(2-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)urea
CAS 1796969-95-3C18H19N5O2