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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(c1cn(-c2ccccc2)c(=S)s1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cn(-c2ccccc2)c(=S)s1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Piperidine, 1-((4-amino-2,3-dihydro-3-phenyl-2-thioxo-5-thiazolyl)carbonyl)- chemical structure, C15H17N3OS2, CAS 57036-89-2
Piperidine, 1-((4-amino-2,3-dihydro-3-phenyl-2-thioxo-5-thiazolyl)carbonyl)-
CAS 57036-89-2C15H17N3OS2
4-Amino-3-(4-methoxyphenyl)-5-(1-piperidinylcarbonyl)-1,3-thiazole-2(3H)-thione chemical structure, C16H19N3O2S2, CAS 519013-41-3
4-Amino-3-(4-methoxyphenyl)-5-(1-piperidinylcarbonyl)-1,3-thiazole-2(3H)-thione
CAS 519013-41-3C16H19N3O2S2
Piperidine, 1-((4-amino-2,3-dihydro-3-(4-methylphenyl)-2-thioxo-5-thiazolyl)carbonyl)- chemical structure, C16H19N3OS2, CAS 57037-02-2
Piperidine, 1-((4-amino-2,3-dihydro-3-(4-methylphenyl)-2-thioxo-5-thiazolyl)carbonyl)-
CAS 57037-02-2C16H19N3OS2
Piperidine, 1-((4-amino-2,3-dihydro-3-(2-methylphenyl)-2-thioxo-5-thiazolyl)carbonyl)- chemical structure, C16H19N3OS2, CAS 57036-93-8
Piperidine, 1-((4-amino-2,3-dihydro-3-(2-methylphenyl)-2-thioxo-5-thiazolyl)carbonyl)-
CAS 57036-93-8C16H19N3OS2
Piperidine, 1-((4-amino-2,3-dihydro-3-(3-methylphenyl)-2-thioxo-5-thiazolyl)carbonyl)- chemical structure, C16H19N3OS2, CAS 57036-98-3
Piperidine, 1-((4-amino-2,3-dihydro-3-(3-methylphenyl)-2-thioxo-5-thiazolyl)carbonyl)-
CAS 57036-98-3C16H19N3OS2
4-Amino-3-(4-ethylphenyl)-5-(piperidine-1-carbonyl)-2,3-dihydro-1,3-thiazole-2-thione chemical structure, C17H21N3OS2, CAS 879950-69-3
4-Amino-3-(4-ethylphenyl)-5-(piperidine-1-carbonyl)-2,3-dihydro-1,3-thiazole-2-thione
CAS 879950-69-3C17H21N3OS2
4-Amino-3-(5-chloro-2-methoxyphenyl)-5-(piperidine-1-carbonyl)-2,3-dihydro-1,3-thiazole-2-thione chemical structure, C16H18ClN3O2S2, CAS 1021252-71-0
4-Amino-3-(5-chloro-2-methoxyphenyl)-5-(piperidine-1-carbonyl)-2,3-dihydro-1,3-thiazole-2-thione
CAS 1021252-71-0C16H18ClN3O2S2
Methyl 3-[4-amino-5-(piperidine-1-carbonyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazol-3-yl]-4-methylbenzoate chemical structure, C18H21N3O3S2, CAS 1021252-89-0
Methyl 3-[4-amino-5-(piperidine-1-carbonyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazol-3-yl]-4-methylbenzoate
CAS 1021252-89-0C18H21N3O3S2
(4-Amino-3-(4-chlorophenyl)-2-thioxo-2,3-dihydrothiazol-5-yl)(piperidin-1-yl)methanone chemical structure, C15H16ClN3OS2, CAS 946301-51-5
(4-Amino-3-(4-chlorophenyl)-2-thioxo-2,3-dihydrothiazol-5-yl)(piperidin-1-yl)methanone
CAS 946301-51-5C15H16ClN3OS2
(4-Amino-3-(3-chloro-4-fluorophenyl)-2-thioxo-2,3-dihydrothiazol-5-yl)(piperidin-1-yl)methanone chemical structure, C15H15ClFN3OS2, CAS 946355-92-6
(4-Amino-3-(3-chloro-4-fluorophenyl)-2-thioxo-2,3-dihydrothiazol-5-yl)(piperidin-1-yl)methanone
CAS 946355-92-6C15H15ClFN3OS2