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Murcko scaffold

Ring system with 3 rings and 23 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
12
With full pages
6
Scaffold SMILES

O=C(NNC(=O)c1cc2ccccc2[nH]c1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NNC(=O)c1cc2ccccc2[nH]c1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N'-(2,4-Dichlorobenzoyl)-1-ET-4-HO-2-oxo-1,2-dihydro-3-quinolinecarbohydrazide chemical structure, C19H15Cl2N3O4, CAS 302904-34-3
N'-(2,4-Dichlorobenzoyl)-1-ET-4-HO-2-oxo-1,2-dihydro-3-quinolinecarbohydrazide
CAS 302904-34-3C19H15Cl2N3O4
2-Hydroxy-N'-(3-nitrobenzoyl)-4-oxo-1H-quinoline-3-carbohydrazide chemical structure, C17H12N4O6, CAS 304870-09-5
2-Hydroxy-N'-(3-nitrobenzoyl)-4-oxo-1H-quinoline-3-carbohydrazide
CAS 304870-09-5C17H12N4O6
N'-(4-Bromobenzoyl)-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarbohydrazide chemical structure, C17H12BrN3O4, CAS 305862-77-5
N'-(4-Bromobenzoyl)-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarbohydrazide
CAS 305862-77-5C17H12BrN3O4
N'-Benzoyl-1-ethyl-4-hydroxy-2-oxoquinoline-3-carbohydrazide chemical structure, C19H17N3O4, CAS 331963-41-8
N'-Benzoyl-1-ethyl-4-hydroxy-2-oxoquinoline-3-carbohydrazide
CAS 331963-41-8C19H17N3O4
4-Hydroxy-1-methyl-N'-[(3-methylphenyl)-oxomethyl]-2-oxo-3-quinolinecarbohydrazide chemical structure, C19H17N3O4, CAS 331963-55-4
4-Hydroxy-1-methyl-N'-[(3-methylphenyl)-oxomethyl]-2-oxo-3-quinolinecarbohydrazide
CAS 331963-55-4C19H17N3O4
N'-Benzoyl-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide chemical structure, C20H19N3O4, CAS 300805-42-9
N'-Benzoyl-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide
CAS 300805-42-9C20H19N3O4
N'-(4-Bromobenzoyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydro-3-quinolinecarbohydrazide chemical structure, C20H18BrN3O4, CAS 317843-71-3
N'-(4-Bromobenzoyl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydro-3-quinolinecarbohydrazide
CAS 317843-71-3C20H18BrN3O4
4-Hydroxy-N'-(4-methylbenzoyl)-2-oxo-1-propyl-1,2-dihydro-3-quinolinecarbohydrazide chemical structure, C21H21N3O4, CAS 371227-21-3
4-Hydroxy-N'-(4-methylbenzoyl)-2-oxo-1-propyl-1,2-dihydro-3-quinolinecarbohydrazide
CAS 371227-21-3C21H21N3O4
4-Hydroxy-N'-{4-nitrobenzoyl}-2-oxo-1-propyl-1,2-dihydro-3-quinolinecarbohydrazide chemical structure, C20H18N4O6, CAS 353253-00-6
4-Hydroxy-N'-{4-nitrobenzoyl}-2-oxo-1-propyl-1,2-dihydro-3-quinolinecarbohydrazide
CAS 353253-00-6C20H18N4O6
4-Hydroxy-N'-[(2-nitrophenyl)carbonyl]-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide chemical structure, C20H18N4O6, CAS 368433-32-3
4-Hydroxy-N'-[(2-nitrophenyl)carbonyl]-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide
CAS 368433-32-3C20H18N4O6
N'-[(3-Chlorophenyl)carbonyl]-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide chemical structure, C20H18ClN3O4, CAS 317840-27-0
N'-[(3-Chlorophenyl)carbonyl]-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide
CAS 317840-27-0C20H18ClN3O4
4-Hydroxy-N'-[(3-nitrophenyl)carbonyl]-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide chemical structure, C20H18N4O6, CAS 300839-89-8
4-Hydroxy-N'-[(3-nitrophenyl)carbonyl]-2-oxo-1-propyl-1,2-dihydroquinoline-3-carbohydrazide
CAS 300839-89-8C20H18N4O6