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Murcko scaffold

Ring system with 2 rings and 8 atoms

33 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 8
Chemicals: 33
With full pages: 3

Scaffold SMILES

C1CSC2(C1)CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold C1CSC2(C1)CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

2-(tert-Butoxycarbonyl)-5-thia-2-azaspiro[3.4]octane-8-carboxylic acid chemical structure, C12H19NO4S, CAS 1373029-39-0

2-(tert-Butoxycarbonyl)-5-thia-2-azaspiro[3.4]octane-8-carboxylic acid

CAS 1373029-39-0C₁₂H₁₉NO₄S

tert-Butyl 8-(hydroxymethyl)-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C12H21NO3S, CAS 1373029-00-5

tert-Butyl 8-(hydroxymethyl)-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 1373029-00-5C₁₂H₂₁NO₃S

tert-Butyl 8-(aminomethyl)-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C12H22N2O2S, CAS 1373029-16-3

tert-Butyl 8-(aminomethyl)-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 1373029-16-3C₁₂H₂₂N₂O₂S

tert-Butyl 8-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H19NO3S, CAS 1340481-89-1

tert-Butyl 8-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 1340481-89-1C₁₁H₁₉NO₃S

tert-Butyl 7-hydroxy-5-thia-2-azaspiro(3.4)octane-2-carboxylate chemical structure, C11H19NO3S, CAS 1453315-70-2

tert-Butyl 7-hydroxy-5-thia-2-azaspiro(3.4)octane-2-carboxylate

CAS 1453315-70-2C₁₁H₁₉NO₃S

tert-Butyl 7-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H20N2O2S, CAS 1934265-93-6

tert-Butyl 7-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 1934265-93-6C₁₁H₂₀N₂O₂S

tert-Butyl 7-(methylamino)-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C12H22N2O2S, CAS 2089700-97-8

tert-Butyl 7-(methylamino)-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2089700-97-8C₁₂H₂₂N₂O₂S

7,7-Difluoro-5-thia-2-azaspiro[3.4]octane chemical structure, C6H9F2NS, CAS 1823252-82-9

7,7-Difluoro-5-thia-2-azaspiro[3.4]octane

CAS 1823252-82-9C₆H₉F₂NS

2-tert-Butyl 8-methyl 5-thia-2-azaspiro[3.4]octane-2,8-dicarboxylate chemical structure, C13H21NO4S, CAS 1823264-51-2

2-tert-Butyl 8-methyl 5-thia-2-azaspiro[3.4]octane-2,8-dicarboxylate

CAS 1823264-51-2C₁₃H₂₁NO₄S

tert-Butyl (8R)-8-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H20N2O2S, CAS 2199215-57-9

tert-Butyl (8R)-8-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2199215-57-9C₁₁H₂₀N₂O₂S

tert-Butyl (8S)-8-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H20N2O2S, CAS 2381538-74-3

tert-Butyl (8S)-8-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2381538-74-3C₁₁H₂₀N₂O₂S

tert-Butyl (7R)-7-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H20N2O2S, CAS 2198241-60-8

tert-Butyl (7R)-7-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2198241-60-8C₁₁H₂₀N₂O₂S

tert-Butyl (7S)-7-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H20N2O2S, CAS 2381107-87-3

tert-Butyl (7S)-7-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2381107-87-3C₁₁H₂₀N₂O₂S

tert-Butyl (8R)-8-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H19NO3S, CAS 2200551-44-4

tert-Butyl (8R)-8-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2200551-44-4C₁₁H₁₉NO₃S

tert-Butyl (8S)-8-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H19NO3S, CAS 2381096-94-0

tert-Butyl (8S)-8-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2381096-94-0C₁₁H₁₉NO₃S

tert-Butyl (7R)-7-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H19NO3S, CAS 2202263-23-6

tert-Butyl (7R)-7-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2202263-23-6C₁₁H₁₉NO₃S

tert-Butyl (7S)-7-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H19NO3S, CAS 2382346-91-8

tert-Butyl (7S)-7-hydroxy-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 2382346-91-8C₁₁H₁₉NO₃S

tert-Butyl 8-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate chemical structure, C11H20N2O2S, CAS 1934243-43-2

tert-Butyl 8-amino-5-thia-2-azaspiro[3.4]octane-2-carboxylate

CAS 1934243-43-2C₁₁H₂₀N₂O₂S

5-Thia-2-azaspiro[3.4]octan-7-ol chemical structure, C6H11NOS, CAS 1934275-80-5

5-Thia-2-azaspiro[3.4]octan-7-ol

CAS 1934275-80-5C₆H₁₁NOS

7,7-Difluoro-5-thia-2-azaspiro[3.4]octane hydrochloride chemical structure, C6H10ClF2NS, CAS 2177264-66-1

7,7-Difluoro-5-thia-2-azaspiro[3.4]octane hydrochloride

CAS 2177264-66-1C₆H₁₀ClF₂NS

7-Fluoro-5-thia-2-azaspiro[3.4]octane Hydrochloride chemical structure, C6H11ClFNS, CAS 2177259-45-7

7-Fluoro-5-thia-2-azaspiro[3.4]octane Hydrochloride

CAS 2177259-45-7C₆H₁₁ClFNS

Methyl 5-thia-2-azaspiro[3.4]octane-8-carboxylate hydrochloride chemical structure, C8H14ClNO2S, CAS 2225146-80-3

Methyl 5-thia-2-azaspiro[3.4]octane-8-carboxylate hydrochloride

CAS 2225146-80-3C₈H₁₄ClNO₂S

Methyl 5-thia-2-azaspiro[3.4]octane-8-carboxylate chemical structure, C8H13NO2S, CAS 2225143-95-1

Methyl 5-thia-2-azaspiro[3.4]octane-8-carboxylate

CAS 2225143-95-1C₈H₁₃NO₂S

Ethyl 5-thia-2-azaspiro[3.4]octane-8-carboxylate chemical structure, C9H15NO2S, CAS 2287273-72-5

Ethyl 5-thia-2-azaspiro[3.4]octane-8-carboxylate

CAS 2287273-72-5C₉H₁₅NO₂S