Murcko scaffold
2,6-Diazaspiro[3.4]octan-7-one scaffold
41 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 41
- With full pages
- 7
Scaffold SMILES
O=C1CC2(CNC2)CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 41 of 41 chemicals
1,1-Dimethylethyl 7-oxo-2,6-diazaspiro(3.4)octane-2-carboxylate
CAS 1234616-51-3C11H18N2O3
![2,6-Diazaspiro[3.4]octan-7-one chemical structure, C6H10N2O, CAS 1211515-65-9](/s/GZTLCSVTDYAMCZ-UHFFFAOYSA-N.svg)
2,6-Diazaspiro[3.4]octan-7-one
CAS 1211515-65-9C6H10N2O
![2-[(tert-Butoxy)carbonyl]-7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylic acid chemical structure, C12H18N2O5, CAS 1357351-94-0](/s/GACUCUWAYVAYIW-UHFFFAOYSA-N.svg)
2-[(tert-Butoxy)carbonyl]-7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylic acid
CAS 1357351-94-0C12H18N2O5
![tert-Butyl 5-(hydroxymethyl)-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate chemical structure, C12H20N2O4, CAS 1357353-37-7](/s/MDXFMIQUBXXNON-UHFFFAOYSA-N.svg)
tert-Butyl 5-(hydroxymethyl)-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate
CAS 1357353-37-7C12H20N2O4
![2,6-Diazaspiro[3.4]octan-7-one oxalate chemical structure, C8H12N2O5, CAS 1588440-97-4](/s/PRWNGIQBMCOERR-UHFFFAOYSA-N.svg)
2,6-Diazaspiro[3.4]octan-7-one oxalate
CAS 1588440-97-4C8H12N2O5
![2,6-Diazaspiro[3.4]octan-7-one hydrochloride chemical structure, C6H11ClN2O, CAS 1956355-12-6](/s/YXHFTLCRQIGGIT-UHFFFAOYSA-N.svg)
2,6-Diazaspiro[3.4]octan-7-one hydrochloride
CAS 1956355-12-6C6H11ClN2O
![6-Methyl-2,6-diazaspiro[3.4]octan-7-one chemical structure, C7H12N2O, CAS 1936069-27-0](/s/MMKFVFCOYMNYGN-UHFFFAOYSA-N.svg)
6-Methyl-2,6-diazaspiro[3.4]octan-7-one
CAS 1936069-27-0C7H12N2O
![2-t-Butyl 5-ethyl 7-oxo-2,6-diazaspiro[3.4]octane-2,5-dicarboxylate chemical structure, C14H22N2O5, CAS 1357351-87-1](/s/HVOJRYNWIYULON-UHFFFAOYSA-N.svg)
2-t-Butyl 5-ethyl 7-oxo-2,6-diazaspiro[3.4]octane-2,5-dicarboxylate
CAS 1357351-87-1C14H22N2O5
![(tert-Butyl carbonic) 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylic anhydride chemical structure, C12H18N2O5, CAS 2718843-03-7](/s/YGRLVQBMRICSEV-UHFFFAOYSA-N.svg)
(tert-Butyl carbonic) 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylic anhydride
CAS 2718843-03-7C12H18N2O5
![6-Methyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride chemical structure, C7H13ClN2O, CAS 2097951-61-4](/s/HRENNFLBJMIXPU-UHFFFAOYSA-N.svg)
6-Methyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride
CAS 2097951-61-4C7H13ClN2O
![5,6-Dimethyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride chemical structure, C8H15ClN2O, CAS 2098097-88-0](/s/MFVRQCCMEDOSFN-UHFFFAOYSA-N.svg)
5,6-Dimethyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride
CAS 2098097-88-0C8H15ClN2O
![5,5,6-Trimethyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride chemical structure, C9H17ClN2O, CAS 2098135-24-9](/s/GVIOQXQXXCVSLK-UHFFFAOYSA-N.svg)
5,5,6-Trimethyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride
CAS 2098135-24-9C9H17ClN2O
![5,5,6-Trimethyl-2,6-diazaspiro[3.4]octan-7-one chemical structure, C9H16N2O, CAS 2098135-23-8](/s/SGOQLSRBUWAQJV-UHFFFAOYSA-N.svg)
5,5,6-Trimethyl-2,6-diazaspiro[3.4]octan-7-one
CAS 2098135-23-8C9H16N2O
![5-Methyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride chemical structure, C7H13ClN2O, CAS 2098032-82-5](/s/WXWGSOPYMOOTOR-UHFFFAOYSA-N.svg)
5-Methyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride
CAS 2098032-82-5C7H13ClN2O
![5-Methyl-2,6-diazaspiro[3.4]octan-7-one chemical structure, C7H12N2O, CAS 2098032-81-4](/s/IGSLCIJXHHHVNL-UHFFFAOYSA-N.svg)
5-Methyl-2,6-diazaspiro[3.4]octan-7-one
CAS 2098032-81-4C7H12N2O
![5,5-Dimethyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride chemical structure, C8H15ClN2O, CAS 2097951-79-4](/s/FKXRGQHPXIADAL-UHFFFAOYSA-N.svg)
5,5-Dimethyl-2,6-diazaspiro[3.4]octan-7-one hydrochloride
CAS 2097951-79-4C8H15ClN2O
![5,5-Dimethyl-2,6-diazaspiro[3.4]octan-7-one chemical structure, C8H14N2O, CAS 2097951-78-3](/s/AXMDEGWYMLFSGK-UHFFFAOYSA-N.svg)
5,5-Dimethyl-2,6-diazaspiro[3.4]octan-7-one
CAS 2097951-78-3C8H14N2O
![tert-Butyl 5-(fluoromethyl)-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate chemical structure, C12H19FN2O3, CAS 1357351-92-8](/s/ZAXZNHLBGPZGMU-UHFFFAOYSA-N.svg)
tert-Butyl 5-(fluoromethyl)-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate
CAS 1357351-92-8C12H19FN2O3
![2-Acetyl-2,6-diazaspiro[3.4]octan-7-one chemical structure, C8H12N2O2, CAS 1862810-56-7](/s/OGYBBWFRXZIGSO-UHFFFAOYSA-N.svg)
2-Acetyl-2,6-diazaspiro[3.4]octan-7-one
CAS 1862810-56-7C8H12N2O2
![2,6-Diazaspiro[3.4]octan-7-one, trifluoroacetic acid chemical structure, C8H11F3N2O3, CAS 2228784-02-7](/s/MPNPHRMKZTUFGZ-UHFFFAOYSA-N.svg)
2,6-Diazaspiro[3.4]octan-7-one, trifluoroacetic acid
CAS 2228784-02-7C8H11F3N2O3
8,8-Difluoro-6-methyl-2,6-diazaspiro(3.4)octan-7-one, trifluoroacetic acid
CAS 2193067-09-1C9H11F5N2O3
![8,8-Difluoro-6-methyl-2,6-diazaspiro[3.4]octan-7-one chemical structure, C7H10F2N2O, CAS 2167455-13-0](/s/CLAADPCWMZCEPC-UHFFFAOYSA-N.svg)
8,8-Difluoro-6-methyl-2,6-diazaspiro[3.4]octan-7-one
CAS 2167455-13-0C7H10F2N2O
![tert-Butyl 7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylate chemical structure, C11H18N2O3, CAS 2287262-56-8](/s/JFQXBABMZJZVNC-UHFFFAOYSA-N.svg)
tert-Butyl 7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylate
CAS 2287262-56-8C11H18N2O3
![Ethyl 7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylate chemical structure, C9H14N2O3, CAS 2287260-07-3](/s/UWARBGXHCRAFQE-UHFFFAOYSA-N.svg)
Ethyl 7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylate
CAS 2287260-07-3C9H14N2O3
- Methyl 7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylate2287262-76-2C8H12N2O3
- 7-Oxo-2,6-diazaspiro[3.4]octane-5-carboxylic acid2287261-92-9C7H10N2O3
- 2-Methyl-2,6-diazaspiro[3.4]octan-7-one2166883-53-8C7H12N2O
- 2-Prop-2-enoyl-2,7-diazaspiro[3.4]octan-6-one2305498-87-5C9H12N2O2
- 2-[(tert-Butoxy)carbonyl]-7-oxo-2,6-diazaspiro[3.4]octane-8-carboxylic acid2548983-72-6C12H18N2O5
- 2-tert-Butyl 8-methyl 7-oxo-2,6-diazaspiro[3.4]octane-2,8-dicarboxylate2504203-78-3C13H20N2O5
- 6-Methyl-2,6-diazaspiro[3.4]octan-7-one, trifluoroacetic acid2504202-17-7C9H13F3N2O3
- 5,5-Dimethyl-2,6-diazaspiro[3.4]octan-7-one 4-methylbenzenesulfonate2682112-95-2C15H22N2O4S
- tert-Butyl 5-methyl-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate2172536-18-2C12H20N2O3
- 7-Oxo-2-(2,2,2-trifluoroacetyl)-2,6-diazaspiro[3.4]octane-5-carboxylic acid2757874-47-6C9H9F3N2O4
- 2-Acetyl-7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylic acid2757891-86-2C9H12N2O4
- 8-Amino-2,6-diazaspiro[3.4]octan-7-one2137510-52-0C6H11N3O
- Prop-2-en-1-yl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate2680773-90-2C10H14N2O3
- 7-Oxo-2-[(prop-2-en-1-yloxy)carbonyl]-2,6-diazaspiro[3.4]octane-5-carboxylic acid2680561-09-3C11H14N2O5
- Prop-2-en-1-yl 8,8-difluoro-6-methyl-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate2680799-50-0C11H14F2N2O3
- 2-(Trifluoroacetyl)-2,6-diazaspiro[3.4]octan-7-one2840250-36-2C8H9F3N2O2
- tert-Butyl 8,8-difluoro-6-methyl-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate2386057-29-8C12H18F2N2O3
Related scaffolds
Same ring framework with different atoms or bond orders
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