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Murcko scaffold

Ring system with 3 rings and 21 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
10
With full pages
4
Scaffold SMILES

O=S(=O)(c1ccccc1)c1csc(Nc2ccccc2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1csc(Nc2ccccc2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

5-Chloro-4-(4-methylbenzenesulfonyl)-N-(2-methylphenyl)-1,3-thiazol-2-amine chemical structure, C17H15ClN2O2S2, CAS 305853-73-0
5-Chloro-4-(4-methylbenzenesulfonyl)-N-(2-methylphenyl)-1,3-thiazol-2-amine
CAS 305853-73-0C17H15ClN2O2S2
5-Chloro-4-(4-methylphenyl)sulfonyl-N-phenyl-2-thiazolamine chemical structure, C16H13ClN2O2S2, CAS 153941-64-1
5-Chloro-4-(4-methylphenyl)sulfonyl-N-phenyl-2-thiazolamine
CAS 153941-64-1C16H13ClN2O2S2
2-((5-Chloro-4-(phenylsulfonyl)thiazol-2-yl)(phenyl)amino)ethanol chemical structure, C17H15ClN2O3S2, CAS 745026-58-8
2-((5-Chloro-4-(phenylsulfonyl)thiazol-2-yl)(phenyl)amino)ethanol
CAS 745026-58-8C17H15ClN2O3S2
5-Chloro-N-(4-methoxyphenyl)-4-(4-methylbenzenesulfonyl)-1,3-thiazol-2-amine chemical structure, C17H15ClN2O3S2, CAS 153941-65-2
5-Chloro-N-(4-methoxyphenyl)-4-(4-methylbenzenesulfonyl)-1,3-thiazol-2-amine
CAS 153941-65-2C17H15ClN2O3S2
N-(4-Bromophenyl)-5-chloro-4-(4-chlorobenzenesulfonyl)-1,3-thiazol-2-amine chemical structure, C15H9BrCl2N2O2S2, CAS 327081-70-9
N-(4-Bromophenyl)-5-chloro-4-(4-chlorobenzenesulfonyl)-1,3-thiazol-2-amine
CAS 327081-70-9C15H9BrCl2N2O2S2
5-Chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine chemical structure, C15H8Cl2F2N2O2S2, CAS 327081-71-0
5-Chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
CAS 327081-71-0C15H8Cl2F2N2O2S2
2-((5-Chloro-4-tosylthiazol-2-yl)amino)benzamide chemical structure, C17H14ClN3O3S2, CAS 380446-27-5
2-((5-Chloro-4-tosylthiazol-2-yl)amino)benzamide
CAS 380446-27-5C17H14ClN3O3S2
3-((5-Chloro-4-(phenylsulfonyl)thiazol-2-yl)amino)phenol chemical structure, C15H11ClN2O3S2, CAS 736189-24-5
3-((5-Chloro-4-(phenylsulfonyl)thiazol-2-yl)amino)phenol
CAS 736189-24-5C15H11ClN2O3S2
4-(Benzenesulfonyl)-5-chloro-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine chemical structure, C15H9ClF2N2O2S2, CAS 869465-03-2
4-(Benzenesulfonyl)-5-chloro-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
CAS 869465-03-2C15H9ClF2N2O2S2
4-{[4-(Benzenesulfonyl)-5-chloro-1,3-thiazol-2-yl](methyl)amino}phenol chemical structure, C16H13ClN2O3S2, CAS 874124-14-8
4-{[4-(Benzenesulfonyl)-5-chloro-1,3-thiazol-2-yl](methyl)amino}phenol
CAS 874124-14-8C16H13ClN2O3S2