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Murcko scaffold

1,8-Diazaspiro(4.5)decan-2-one scaffold

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
18
With full pages
4
Scaffold SMILES

O=C1CCC2(CCNCC2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,8-Diazaspiro(4.5)decan-2-one page
Murcko scaffold O=C1CCC2(CCNCC2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

8-(tert-Butyl) 4-methyl 2-oxo-1,8-diazaspiro[4.5]decane-4,8-dicarboxylate chemical structure, C15H24N2O5, CAS 959062-73-8
8-(tert-Butyl) 4-methyl 2-oxo-1,8-diazaspiro[4.5]decane-4,8-dicarboxylate
CAS 959062-73-8C15H24N2O5
1,8-Diazaspiro(4.5)decan-2-one chemical structure, C8H14N2O, CAS 1158749-93-9
1,8-Diazaspiro(4.5)decan-2-one
CAS 1158749-93-9C8H14N2O
tert-Butyl 3-methyl-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C14H24N2O3, CAS 1234481-61-8
tert-Butyl 3-methyl-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1234481-61-8C14H24N2O3
1-Methyl-1,8-diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C9H17ClN2O, CAS 1380300-63-9
1-Methyl-1,8-diazaspiro[4.5]decan-2-one hydrochloride
CAS 1380300-63-9C9H17ClN2O
1-Methyl-1,8-diazaspiro[4.5]decan-2-one chemical structure, C9H16N2O, CAS 1380386-88-8
1-Methyl-1,8-diazaspiro[4.5]decan-2-one
CAS 1380386-88-8C9H16N2O
1-Ethyl-1,8-diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C10H19ClN2O, CAS 1380300-51-5
1-Ethyl-1,8-diazaspiro[4.5]decan-2-one hydrochloride
CAS 1380300-51-5C10H19ClN2O
1-Ethyl-1,8-diazaspiro[4.5]decan-2-one chemical structure, C10H18N2O, CAS 1380386-83-3
1-Ethyl-1,8-diazaspiro[4.5]decan-2-one
CAS 1380386-83-3C10H18N2O
1,8-Diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C8H15ClN2O, CAS 1389313-57-8
1,8-Diazaspiro[4.5]decan-2-one hydrochloride
CAS 1389313-57-8C8H15ClN2O
tert-Butyl 2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C13H22N2O3, CAS 1158749-94-0
tert-Butyl 2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1158749-94-0C13H22N2O3
1,8-Diazaspiro[4.5]decan-2-one dihydrochloride chemical structure, C8H16Cl2N2O, CAS 1956389-84-6
1,8-Diazaspiro[4.5]decan-2-one dihydrochloride
CAS 1956389-84-6C8H16Cl2N2O
1-Methyl-1,8-diazaspiro[4.5]decan-2-one dihydrochloride chemical structure, C9H18Cl2N2O, CAS 1609407-01-3
1-Methyl-1,8-diazaspiro[4.5]decan-2-one dihydrochloride
CAS 1609407-01-3C9H18Cl2N2O
1-(2-Methoxyethyl)-1,8-diazaspiro[4.5]decan-2-one chemical structure, C11H20N2O2, CAS 1422140-97-3
1-(2-Methoxyethyl)-1,8-diazaspiro[4.5]decan-2-one
CAS 1422140-97-3C11H20N2O2
8-Boc-1-methyl-1,8-diazaspiro[4.5]decan-2-one chemical structure, C14H24N2O3, CAS 2066588-57-4
8-Boc-1-methyl-1,8-diazaspiro[4.5]decan-2-one
CAS 2066588-57-4C14H24N2O3
Methyl 3-(8-acetyl-2-oxo-1,8-diazaspiro[4.5]decan-3-yl)-2-aminopropanoate chemical structure, C14H23N3O4, CAS 2723434-40-8
Methyl 3-(8-acetyl-2-oxo-1,8-diazaspiro[4.5]decan-3-yl)-2-aminopropanoate
CAS 2723434-40-8C14H23N3O4
tert-Butyl 2-oxo-3-(propan-2-yl)-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C16H28N2O3, CAS 2138208-67-8
tert-Butyl 2-oxo-3-(propan-2-yl)-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 2138208-67-8C16H28N2O3
tert-Butyl 3-(2-methylpropyl)-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C17H30N2O3, CAS 2138208-72-5
tert-Butyl 3-(2-methylpropyl)-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 2138208-72-5C17H30N2O3
tert-Butyl 3-(2,2-dimethylpropyl)-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C18H32N2O3, CAS 2138513-81-0
tert-Butyl 3-(2,2-dimethylpropyl)-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 2138513-81-0C18H32N2O3
tert-Butyl 3-ethyl-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C15H26N2O3, CAS 2138367-64-1
tert-Butyl 3-ethyl-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate
CAS 2138367-64-1C15H26N2O3