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Murcko scaffold

Ring system with 3 rings and 18 atoms

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
48
With full pages
3
Scaffold SMILES

c1ccc(-c2nc(CN3CCCCC3)co2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nc(CN3CCCCC3)co2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

1-[[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl]-N-[2-(dipropylamino)ethyl]piperidine-4-carboxamide chemical structure, C25H37ClN4O2, CAS 902618-54-6
1-[[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl]-N-[2-(dipropylamino)ethyl]piperidine-4-carboxamide
CAS 902618-54-6C25H37ClN4O2
1-((5-Methyl-2-(o-tolyl)oxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C18H22N2O3, CAS 897765-48-9
1-((5-Methyl-2-(o-tolyl)oxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 897765-48-9C18H22N2O3
1-{[2-(4-Ethylphenyl)-5-methyl-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid chemical structure, C19H24N2O3, CAS 897769-44-7
1-{[2-(4-Ethylphenyl)-5-methyl-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid
CAS 897769-44-7C19H24N2O3
1-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C17H19ClN2O3, CAS 897765-44-5
1-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 897765-44-5C17H19ClN2O3
1-{[2-(2-Ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid chemical structure, C19H24N2O4, CAS 1119452-24-2
1-{[2-(2-Ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid
CAS 1119452-24-2C19H24N2O4
1-{[2-(4-Isopropylphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}piperidine-4-carboxylic acid chemical structure, C20H26N2O3, CAS 1119451-20-5
1-{[2-(4-Isopropylphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}piperidine-4-carboxylic acid
CAS 1119451-20-5C20H26N2O3
1-{[5-Methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid chemical structure, C18H22N2O3, CAS 1119450-03-1
1-{[5-Methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid
CAS 1119450-03-1C18H22N2O3
1-[(5-Methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-piperidine-4-carboxylic acid chemical structure, C17H20N2O3, CAS 1119452-87-7
1-[(5-Methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-piperidine-4-carboxylic acid
CAS 1119452-87-7C17H20N2O3
1-{[5-Methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid chemical structure, C18H22N2O3, CAS 1119451-22-7
1-{[5-Methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]-methyl}piperidine-4-carboxylic acid
CAS 1119451-22-7C18H22N2O3
(R)-1-((2-(4-Chlorophenyl)oxazol-4-yl)methyl)piperidin-3-ol chemical structure, C15H17ClN2O2, CAS 2369269-12-3
(R)-1-((2-(4-Chlorophenyl)oxazol-4-yl)methyl)piperidin-3-ol
CAS 2369269-12-3C15H17ClN2O2
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidine-3-carboxylic acid chemical structure, C16H18N2O3, CAS 1155616-11-7
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidine-3-carboxylic acid
CAS 1155616-11-7C16H18N2O3
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidine-2-carboxylic acid chemical structure, C16H18N2O3, CAS 1218557-77-7
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidine-2-carboxylic acid
CAS 1218557-77-7C16H18N2O3
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidine-4-carboxylic acid chemical structure, C16H18N2O3, CAS 1153237-31-0
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidine-4-carboxylic acid
CAS 1153237-31-0C16H18N2O3
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidin-4-amine chemical structure, C15H19N3O, CAS 1154260-99-7
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidin-4-amine
CAS 1154260-99-7C15H19N3O
1-[(5-Methyl-2-phenyl-1,3-oxazol-4-yl)methyl]piperidine-3-carboxylic acid chemical structure, C17H20N2O3, CAS 1171045-22-9
1-[(5-Methyl-2-phenyl-1,3-oxazol-4-yl)methyl]piperidine-3-carboxylic acid
CAS 1171045-22-9C17H20N2O3
1-{[5-Methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}piperidine-3-carboxylic acid chemical structure, C18H22N2O3, CAS 1170791-18-0
1-{[5-Methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}piperidine-3-carboxylic acid
CAS 1170791-18-0C18H22N2O3
1-((2-(2,4-Dimethylphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C19H24N2O3, CAS 1172482-00-6
1-((2-(2,4-Dimethylphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 1172482-00-6C19H24N2O3
1-{[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-N-(2,2-diethoxyethyl)piperidine-3-carboxamide chemical structure, C23H32ClN3O4, CAS 901869-09-8
1-{[2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-N-(2,2-diethoxyethyl)piperidine-3-carboxamide
CAS 901869-09-8C23H32ClN3O4
1-((2-(4-Fluorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C17H19FN2O3, CAS 1285005-03-9
1-((2-(4-Fluorophenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 1285005-03-9C17H19FN2O3
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidin-4-amine hydrochloride chemical structure, C15H20ClN3O, CAS 1803599-54-3
1-[(2-Phenyl-1,3-oxazol-4-yl)methyl]piperidin-4-amine hydrochloride
CAS 1803599-54-3C15H20ClN3O
1-((2-(2-Chloro-6-methylphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C18H21ClN2O3, CAS 1842323-89-0
1-((2-(2-Chloro-6-methylphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 1842323-89-0C18H21ClN2O3
1-((2-(2-Chloro-6-(trifluoromethyl)phenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C18H18ClF3N2O3, CAS 2111829-29-7
1-((2-(2-Chloro-6-(trifluoromethyl)phenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 2111829-29-7C18H18ClF3N2O3
1-((2-(2,6-Dimethoxyphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C19H24N2O5, CAS 2111836-64-5
1-((2-(2,6-Dimethoxyphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 2111836-64-5C19H24N2O5
1-((2-(3,5-Dimethylphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid chemical structure, C19H24N2O3, CAS 2111836-60-1
1-((2-(3,5-Dimethylphenyl)-5-methyloxazol-4-yl)methyl)piperidine-4-carboxylic acid
CAS 2111836-60-1C19H24N2O3