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Murcko scaffold

Ring system with 3 rings and 22 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
9
With full pages
3
Scaffold SMILES

O=C(NCN1CCN(c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCN1CCN(c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}benzamide chemical structure, C18H20FN3O, CAS 430444-80-7
N-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}benzamide
CAS 430444-80-7C18H20FN3O
PD-168077 chemical structure, C20H22N4O, CAS 190383-31-4
PD-168077
CAS 190383-31-4C20H22N4O
4-Methyl-N-[[4-(2-cyanophenyl)piperazino]methyl]benzamide chemical structure, C20H22N4O, CAS 190383-34-7
4-Methyl-N-[[4-(2-cyanophenyl)piperazino]methyl]benzamide
CAS 190383-34-7C20H22N4O
4-Chloro-N-[[4-(2-methoxyphenyl)piperazino]methyl]benzamide chemical structure, C19H22ClN3O2, CAS 190383-38-1
4-Chloro-N-[[4-(2-methoxyphenyl)piperazino]methyl]benzamide
CAS 190383-38-1C19H22ClN3O2
N-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-4-methylbenzamide chemical structure, C20H25N3O2, CAS 190383-32-5
N-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-4-methylbenzamide
CAS 190383-32-5C20H25N3O2
N-[[4-(2-Methoxyphenyl)piperazino]methyl]benzamide chemical structure, C19H23N3O2, CAS 190383-26-7
N-[[4-(2-Methoxyphenyl)piperazino]methyl]benzamide
CAS 190383-26-7C19H23N3O2
N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide maleate chemical structure, C24H26N4O5, CAS 630117-19-0
N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide maleate
CAS 630117-19-0C24H26N4O5
N-[[4-(2-Cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide maleate chemical structure, C24H26N4O5
N-[[4-(2-Cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide maleate
C24H26N4O5
N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide maleate chemical structure, C24H26N4O5
N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide maleate
C24H26N4O5