CompoundList
Sign in
Murcko scaffold

N-[(4-Phenylpiperazin-1-yl)carbonothioyl]benzamide scaffold

50 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
50
With full pages
10
Scaffold SMILES

O=C(NC(=S)N1CCN(c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[(4-Phenylpiperazin-1-yl)carbonothioyl]benzamide page
Murcko scaffold O=C(NC(=S)N1CCN(c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 50 chemicals

N-[4-(4-Fluorophenyl)piperazine-1-carbothioyl]benzamide chemical structure, C18H18FN3OS, CAS 25561-80-2
N-[4-(4-Fluorophenyl)piperazine-1-carbothioyl]benzamide
CAS 25561-80-2C18H18FN3OS
N-[(4-Phenylpiperazin-1-yl)carbonothioyl]benzamide chemical structure, C18H19N3OS, CAS 690689-56-6
N-[(4-Phenylpiperazin-1-yl)carbonothioyl]benzamide
CAS 690689-56-6C18H19N3OS
2,6-Difluoro-N-(4-phenylpiperazine-1-carbothioyl)benzamide chemical structure, C18H17F2N3OS, CAS 497060-84-1
2,6-Difluoro-N-(4-phenylpiperazine-1-carbothioyl)benzamide
CAS 497060-84-1C18H17F2N3OS
N-[4-(5-Chloro-2-methylphenyl)piperazine-1-carbothioyl]-4-methylbenzamide chemical structure, C20H22ClN3OS, CAS 497061-03-7
N-[4-(5-Chloro-2-methylphenyl)piperazine-1-carbothioyl]-4-methylbenzamide
CAS 497061-03-7C20H22ClN3OS
N-[4-(2-Fluorophenyl)piperazine-1-carbothioyl]-4-methylbenzamide chemical structure, C19H20FN3OS, CAS 497061-04-8
N-[4-(2-Fluorophenyl)piperazine-1-carbothioyl]-4-methylbenzamide
CAS 497061-04-8C19H20FN3OS
2-Iodo-N-{[4-(2-methoxyphenyl)-1-piperazinyl]carbothioyl}benzamide chemical structure, C19H20IN3O2S, CAS 447431-82-5
2-Iodo-N-{[4-(2-methoxyphenyl)-1-piperazinyl]carbothioyl}benzamide
CAS 447431-82-5C19H20IN3O2S
2-Chloro-N-[4-(2-methoxyphenyl)piperazine-1-carbothioyl]benzamide chemical structure, C19H20ClN3O2S, CAS 500270-10-0
2-Chloro-N-[4-(2-methoxyphenyl)piperazine-1-carbothioyl]benzamide
CAS 500270-10-0C19H20ClN3O2S
4-(Diethylamino)-N-(4-phenylpiperazine-1-carbothioyl)benzamide chemical structure, C22H28N4OS, CAS 684231-46-7
4-(Diethylamino)-N-(4-phenylpiperazine-1-carbothioyl)benzamide
CAS 684231-46-7C22H28N4OS
N-[4-(2-Hydroxyphenyl)piperazine-1-carbothioyl]-4-methoxybenzamide chemical structure, C19H21N3O3S, CAS 722465-50-1
N-[4-(2-Hydroxyphenyl)piperazine-1-carbothioyl]-4-methoxybenzamide
CAS 722465-50-1C19H21N3O3S
4-Methyl-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide chemical structure, C19H20N4O3S, CAS 425661-08-1
4-Methyl-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide
CAS 425661-08-1C19H20N4O3S
2-Chloro-N-[4-(4-chloro-2-nitrophenyl)piperazine-1-carbothioyl]benzamide chemical structure, C18H16Cl2N4O3S, CAS 425656-48-0
2-Chloro-N-[4-(4-chloro-2-nitrophenyl)piperazine-1-carbothioyl]benzamide
CAS 425656-48-0C18H16Cl2N4O3S
2-Chloro-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide chemical structure, C18H17ClN4O3S, CAS 347336-57-6
2-Chloro-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide
CAS 347336-57-6C18H17ClN4O3S
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-4-fluorobenzamide chemical structure, C18H16ClFN4O3S, CAS 371922-14-4
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-4-fluorobenzamide
CAS 371922-14-4C18H16ClFN4O3S
N-[4-(4-Chloro-2-nitrophenyl)piperazine-1-carbothioyl]-3,4,5-trimethoxybenzamide chemical structure, C21H23ClN4O6S, CAS 371214-09-4
N-[4-(4-Chloro-2-nitrophenyl)piperazine-1-carbothioyl]-3,4,5-trimethoxybenzamide
CAS 371214-09-4C21H23ClN4O6S
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-3,4-dimethoxybenzamide chemical structure, C20H21ClN4O5S, CAS 426222-44-8
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-3,4-dimethoxybenzamide
CAS 426222-44-8C20H21ClN4O5S
N-[4-(4-Chloro-2-nitrophenyl)piperazine-1-carbothioyl]-4-ethoxybenzamide chemical structure, C20H21ClN4O4S, CAS 426228-16-2
N-[4-(4-Chloro-2-nitrophenyl)piperazine-1-carbothioyl]-4-ethoxybenzamide
CAS 426228-16-2C20H21ClN4O4S
2-Iodo-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide chemical structure, C18H17IN4O3S, CAS 426231-17-6
2-Iodo-N-[4-(4-nitrophenyl)piperazine-1-carbothioyl]benzamide
CAS 426231-17-6C18H17IN4O3S
N-[4-(4-Nitrophenyl)piperazine-1-carbothioyl]-4-propan-2-ylbenzamide chemical structure, C21H24N4O3S, CAS 426231-38-1
N-[4-(4-Nitrophenyl)piperazine-1-carbothioyl]-4-propan-2-ylbenzamide
CAS 426231-38-1C21H24N4O3S
3-Chloro-N-[4-(2-chloro-4-nitrophenyl)piperazine-1-carbothioyl]-4-methoxybenzamide chemical structure, C19H18Cl2N4O4S, CAS 428462-08-2
3-Chloro-N-[4-(2-chloro-4-nitrophenyl)piperazine-1-carbothioyl]-4-methoxybenzamide
CAS 428462-08-2C19H18Cl2N4O4S
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-2-fluorobenzamide chemical structure, C18H16ClFN4O3S, CAS 371119-05-0
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-2-fluorobenzamide
CAS 371119-05-0C18H16ClFN4O3S
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-2-methylbenzamide chemical structure, C19H19ClN4O3S, CAS 428464-00-0
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-2-methylbenzamide
CAS 428464-00-0C19H19ClN4O3S
3-Methoxy-N-({4-[2-nitro-4-(trifluoromethyl)phenyl]-1-piperazinyl}carbonothioyl)benzamide chemical structure, C20H19F3N4O4S, CAS 672920-59-1
3-Methoxy-N-({4-[2-nitro-4-(trifluoromethyl)phenyl]-1-piperazinyl}carbonothioyl)benzamide
CAS 672920-59-1C20H19F3N4O4S
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-3,5-dimethoxybenzamide chemical structure, C20H21ClN4O5S, CAS 428475-16-5
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-3,5-dimethoxybenzamide
CAS 428475-16-5C20H21ClN4O5S
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-3-ethoxybenzamide chemical structure, C20H21ClN4O4S, CAS 428472-16-6
N-[4-(2-Chloro-4-nitrophenyl)piperazine-1-carbothioyl]-3-ethoxybenzamide
CAS 428472-16-6C20H21ClN4O4S