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Murcko scaffold

Ring system with 3 rings and 22 atoms

32 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 32
With full pages: 12

Scaffold SMILES

O=C(COc1ccccc1)N1CCN(c2ccccn2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(COc1ccccc1)N1CCN(c2ccccn2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

2-(3-Methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C18H21N3O2, CAS 351418-78-5

2-(3-Methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 351418-78-5C₁₈H₂₁N₃O₂

2-(4-Chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H18ClN3O2, CAS 335282-49-0

2-(4-Chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 335282-49-0C₁₇H₁₈ClN₃O₂

2-(4-Methoxyphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C18H21N3O3, CAS 378754-79-1

2-(4-Methoxyphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 378754-79-1C₁₈H₂₁N₃O₃

2-(2-Methoxyphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C18H21N3O3, CAS 433702-05-7

2-(2-Methoxyphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 433702-05-7C₁₈H₂₁N₃O₃

2-(4-Propan-2-ylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C20H25N3O2, CAS 432534-34-4

2-(4-Propan-2-ylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 432534-34-4C₂₀H₂₅N₃O₂

2-(2,4-Dimethylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C19H23N3O2, CAS 5857-95-4

2-(2,4-Dimethylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 5857-95-4C₁₉H₂₃N₃O₂

2-(3,5-Dimethylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C19H23N3O2, CAS 419553-03-0

2-(3,5-Dimethylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 419553-03-0C₁₉H₂₃N₃O₂

1-(4-Pyridin-2-ylpiperazin-1-yl)-2-(2,3,5-trimethylphenoxy)ethanone chemical structure, C20H25N3O2, CAS 690980-27-9

1-(4-Pyridin-2-ylpiperazin-1-yl)-2-(2,3,5-trimethylphenoxy)ethanone

CAS 690980-27-9C₂₀H₂₅N₃O₂

2-(4-Nitrophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H18N4O4, CAS 701251-79-8

2-(4-Nitrophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 701251-79-8C₁₇H₁₈N₄O₄

2-(2-Bromo-4-ethylphenoxy)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone chemical structure, C19H22BrN3O2, CAS 667878-98-0

2-(2-Bromo-4-ethylphenoxy)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone

CAS 667878-98-0C₁₉H₂₂BrN₃O₂

2-(4-Bromo-2-methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C18H20BrN3O2, CAS 434306-05-5

2-(4-Bromo-2-methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 434306-05-5C₁₈H₂₀BrN₃O₂

2-(4-Bromophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H18BrN3O2, CAS 351418-94-5

2-(4-Bromophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 351418-94-5C₁₇H₁₈BrN₃O₂

2-(4-Bromo-3-methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C18H20BrN3O2, CAS 442555-71-7

2-(4-Bromo-3-methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 442555-71-7C₁₈H₂₀BrN₃O₂

2-(2-Bromo-4-methylphenoxy)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone chemical structure, C18H20BrN3O2, CAS 6083-63-2

2-(2-Bromo-4-methylphenoxy)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone

CAS 6083-63-2C₁₈H₂₀BrN₃O₂

2-(4-tert-Butylphenoxy)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone chemical structure, C21H27N3O2, CAS 420825-18-9

2-(4-tert-Butylphenoxy)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone

CAS 420825-18-9C₂₁H₂₇N₃O₂

2-(2-Bromo-4-chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H17BrClN3O2, CAS 663944-57-8

2-(2-Bromo-4-chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 663944-57-8C₁₇H₁₇BrClN₃O₂

2-(2,4-Dichlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H17Cl2N3O2, CAS 429632-13-3

2-(2,4-Dichlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 429632-13-3C₁₇H₁₇Cl₂N₃O₂

2-(4-Chloro-3,5-dimethylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C19H22ClN3O2, CAS 333441-07-9

2-(4-Chloro-3,5-dimethylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 333441-07-9C₁₉H₂₂ClN₃O₂

2-(4-Bromo-2-chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H17BrClN3O2, CAS 430451-33-5

2-(4-Bromo-2-chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 430451-33-5C₁₇H₁₇BrClN₃O₂

2-(3-Chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one chemical structure, C18H20ClN3O2, CAS 693832-27-8

2-(3-Chlorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one

CAS 693832-27-8C₁₈H₂₀ClN₃O₂

2-(2-Bromo-4-tert-butylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C21H26BrN3O2, CAS 701244-34-0

2-(2-Bromo-4-tert-butylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 701244-34-0C₂₁H₂₆BrN₃O₂

2-(3-Chloro-4-fluorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone chemical structure, C17H17ClFN3O2, CAS 830343-86-7

2-(3-Chloro-4-fluorophenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone

CAS 830343-86-7C₁₇H₁₇ClFN₃O₂

2-(3-Methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one chemical structure, C19H23N3O2, CAS 878699-60-6

2-(3-Methylphenoxy)-1-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one

CAS 878699-60-6C₁₉H₂₃N₃O₂

1-(4-Pyridin-2-yl-piperazin-1-yl)-2-p-tolyloxy-propan-1-one chemical structure, C19H23N3O2, CAS 878699-90-2

1-(4-Pyridin-2-yl-piperazin-1-yl)-2-p-tolyloxy-propan-1-one

CAS 878699-90-2C₁₉H₂₃N₃O₂