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Murcko scaffold

Ring system with 3 rings and 22 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
8
With full pages
6
Scaffold SMILES

O=C(Cn1ccc2ccccc2c1=O)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1ccc2ccccc2c1=O)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-Benzyl-2-(5-methoxy-1-oxoisoquinolin-2-yl)acetamide chemical structure, C19H18N2O3, CAS 868223-67-0
N-Benzyl-2-(5-methoxy-1-oxoisoquinolin-2-yl)acetamide
CAS 868223-67-0C19H18N2O3
N-[(4-Fluorophenyl)methyl]-2-(5-methoxy-1-oxoisoquinolin-2-yl)acetamide chemical structure, C19H17FN2O3, CAS 868223-68-1
N-[(4-Fluorophenyl)methyl]-2-(5-methoxy-1-oxoisoquinolin-2-yl)acetamide
CAS 868223-68-1C19H17FN2O3
Ethyl 2-[2-[2-(benzylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate chemical structure, C22H22N2O5, CAS 868224-22-0
Ethyl 2-[2-[2-(benzylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate
CAS 868224-22-0C22H22N2O5
Ethyl 2-[2-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate chemical structure, C22H21FN2O5, CAS 868224-23-1
Ethyl 2-[2-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate
CAS 868224-23-1C22H21FN2O5
Methyl 2-[2-[2-(benzylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate chemical structure, C21H20N2O5, CAS 868225-25-6
Methyl 2-[2-[2-(benzylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate
CAS 868225-25-6C21H20N2O5
Methyl 2-[2-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate chemical structure, C21H19FN2O5, CAS 868225-26-7
Methyl 2-[2-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxyacetate
CAS 868225-26-7C21H19FN2O5
Ethyl 2-{[2-({[(4-fluorophenyl)methyl]carbamoyl}methyl)-1-oxo-1,2-dihydroisoquinolin-5-yl]oxy}propanoate chemical structure, C23H23FN2O5, CAS 868224-74-2
Ethyl 2-{[2-({[(4-fluorophenyl)methyl]carbamoyl}methyl)-1-oxo-1,2-dihydroisoquinolin-5-yl]oxy}propanoate
CAS 868224-74-2C23H23FN2O5
Ethyl 2-({2-[(benzylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate chemical structure, C23H24N2O5, CAS 868224-73-1
Ethyl 2-({2-[(benzylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate
CAS 868224-73-1C23H24N2O5