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Murcko scaffold

Ring system with 3 rings and 21 atoms

38 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
38
With full pages
3
Scaffold SMILES

O=C(Nc1cnn(Cc2ccccc2)c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cnn(Cc2ccccc2)c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

N-(1-Benzyl-1H-pyrazol-4-yl)-2-nitrobenzamide chemical structure, C17H14N4O3, CAS 514855-89-1
N-(1-Benzyl-1H-pyrazol-4-yl)-2-nitrobenzamide
CAS 514855-89-1C17H14N4O3
N-[1-[(2,6-Dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-3-methylbenzamide chemical structure, C20H19Cl2N3O, CAS 514817-28-8
N-[1-[(2,6-Dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-3-methylbenzamide
CAS 514817-28-8C20H19Cl2N3O
N-[1-[(4-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-3,4-dimethoxybenzamide chemical structure, C21H22FN3O3, CAS 514854-84-3
N-[1-[(4-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-3,4-dimethoxybenzamide
CAS 514854-84-3C21H22FN3O3
2-Ethoxy-N-[1-[(4-fluorophenyl)methyl]pyrazol-4-yl]benzamide chemical structure, C19H18FN3O2, CAS 491829-64-2
2-Ethoxy-N-[1-[(4-fluorophenyl)methyl]pyrazol-4-yl]benzamide
CAS 491829-64-2C19H18FN3O2
4-Bromo-N-[1-[(2,4-dichlorophenyl)methyl]pyrazol-4-yl]benzamide chemical structure, C17H12BrCl2N3O, CAS 514856-84-9
4-Bromo-N-[1-[(2,4-dichlorophenyl)methyl]pyrazol-4-yl]benzamide
CAS 514856-84-9C17H12BrCl2N3O
2-Bromo-N-[1-[(3,4-dichlorophenyl)methyl]pyrazol-4-yl]benzamide chemical structure, C17H12BrCl2N3O, CAS 515119-90-1
2-Bromo-N-[1-[(3,4-dichlorophenyl)methyl]pyrazol-4-yl]benzamide
CAS 515119-90-1C17H12BrCl2N3O
5-Chloro-N-[1-(2,4-dichlorobenzyl)-1H-pyrazol-4-yl]-2-methoxybenzamide chemical structure, C18H14Cl3N3O2, CAS 515828-65-6
5-Chloro-N-[1-(2,4-dichlorobenzyl)-1H-pyrazol-4-yl]-2-methoxybenzamide
CAS 515828-65-6C18H14Cl3N3O2
4-Chloro-N-[1-(2,6-dichlorobenzyl)-1H-pyrazol-4-yl]-2-nitrobenzamide chemical structure, C17H11Cl3N4O3, CAS 515121-06-9
4-Chloro-N-[1-(2,6-dichlorobenzyl)-1H-pyrazol-4-yl]-2-nitrobenzamide
CAS 515121-06-9C17H11Cl3N4O3
2-Chloro-N-[1-(2-chloro-6-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-nitrobenzamide chemical structure, C19H15Cl2FN4O3, CAS 515120-32-8
2-Chloro-N-[1-(2-chloro-6-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-nitrobenzamide
CAS 515120-32-8C19H15Cl2FN4O3
N-[1-[(2-Chloro-6-fluorophenyl)methyl]pyrazol-4-yl]-3,4-dimethoxybenzamide chemical structure, C19H17ClFN3O3, CAS 955900-15-9
N-[1-[(2-Chloro-6-fluorophenyl)methyl]pyrazol-4-yl]-3,4-dimethoxybenzamide
CAS 955900-15-9C19H17ClFN3O3
N-[1-[(2-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-methyl-3,5-dinitrobenzamide chemical structure, C20H18ClN5O5, CAS 957294-44-9
N-[1-[(2-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-methyl-3,5-dinitrobenzamide
CAS 957294-44-9C20H18ClN5O5
2-Bromo-N-[1-[(2-chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]benzamide chemical structure, C19H17BrClN3O, CAS 515123-03-2
2-Bromo-N-[1-[(2-chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]benzamide
CAS 515123-03-2C19H17BrClN3O
N-(1-Benzyl-3,5-dimethylpyrazol-4-yl)-2,4-dinitrobenzamide chemical structure, C19H17N5O5, CAS 957294-41-6
N-(1-Benzyl-3,5-dimethylpyrazol-4-yl)-2,4-dinitrobenzamide
CAS 957294-41-6C19H17N5O5
N-[1-[(2-Chloro-6-fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2,4-dinitrobenzamide chemical structure, C19H15ClFN5O5, CAS 515120-47-5
N-[1-[(2-Chloro-6-fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2,4-dinitrobenzamide
CAS 515120-47-5C19H15ClFN5O5
N-[3,5-Dimethyl-1-[(3-methylphenyl)methyl]pyrazol-4-yl]-4-methoxybenzamide chemical structure, C21H23N3O2, CAS 957265-70-2
N-[3,5-Dimethyl-1-[(3-methylphenyl)methyl]pyrazol-4-yl]-4-methoxybenzamide
CAS 957265-70-2C21H23N3O2
N-[1-[(2,6-Dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2,3,4,5,6-pentafluorobenzamide chemical structure, C19H12Cl2F5N3O, CAS 515846-88-5
N-[1-[(2,6-Dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2,3,4,5,6-pentafluorobenzamide
CAS 515846-88-5C19H12Cl2F5N3O
5-Chloro-N-[1-[(2,4-dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2-nitrobenzamide chemical structure, C19H15Cl3N4O3, CAS 490031-81-7
5-Chloro-N-[1-[(2,4-dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2-nitrobenzamide
CAS 490031-81-7C19H15Cl3N4O3
2-Chloro-N-[1-[(2,4-dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4,5-difluorobenzamide chemical structure, C19H14Cl3F2N3O, CAS 489449-59-4
2-Chloro-N-[1-[(2,4-dichlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4,5-difluorobenzamide
CAS 489449-59-4C19H14Cl3F2N3O
N-[1-[(2-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-methoxy-3-nitrobenzamide chemical structure, C20H19ClN4O4, CAS 515175-31-2
N-[1-[(2-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-methoxy-3-nitrobenzamide
CAS 515175-31-2C20H19ClN4O4
4-Chloro-N-[1-[(4-chlorophenyl)methyl]pyrazol-4-yl]benzamide chemical structure, C17H13Cl2N3O, CAS 515121-95-6
4-Chloro-N-[1-[(4-chlorophenyl)methyl]pyrazol-4-yl]benzamide
CAS 515121-95-6C17H13Cl2N3O
4-Ethoxy-N-[1-[(4-fluorophenyl)methyl]pyrazol-4-yl]benzamide chemical structure, C19H18FN3O2, CAS 515122-49-3
4-Ethoxy-N-[1-[(4-fluorophenyl)methyl]pyrazol-4-yl]benzamide
CAS 515122-49-3C19H18FN3O2
N-(1-Benzylpyrazol-4-yl)-3,4,5-trimethoxybenzamide chemical structure, C20H21N3O4, CAS 515149-05-0
N-(1-Benzylpyrazol-4-yl)-3,4,5-trimethoxybenzamide
CAS 515149-05-0C20H21N3O4
N-[3,5-Dimethyl-1-[(4-methylphenyl)methyl]pyrazol-4-yl]-2-methoxybenzamide chemical structure, C21H23N3O2, CAS 515150-68-2
N-[3,5-Dimethyl-1-[(4-methylphenyl)methyl]pyrazol-4-yl]-2-methoxybenzamide
CAS 515150-68-2C21H23N3O2
N-[1-[(4-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2-iodobenzamide chemical structure, C19H17ClIN3O, CAS 492422-04-5
N-[1-[(4-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2-iodobenzamide
CAS 492422-04-5C19H17ClIN3O