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Murcko scaffold

1-Phenylpiperazine scaffold

6,403 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
6,403
With full pages
595
Scaffold SMILES

c1ccc(N2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenylpiperazine page
Murcko scaffold c1ccc(N2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 817 to 864 of 6,403 chemicals

1-Piperazineethanamine, 4-butyl-alpha-methyl-N-phenyl-, ethanedioate, hydrate (2:4:1) chemical structure, C21H33N3O8, CAS 77562-88-0
1-Piperazineethanamine, 4-butyl-alpha-methyl-N-phenyl-, ethanedioate, hydrate (2:4:1)
CAS 77562-88-0C21H33N3O8
Piperazine, 1-(3-chloropropyl)-4-(3-(trifluoromethyl)phenyl)- chemical structure, C14H18ClF3N2, CAS 78056-40-3
Piperazine, 1-(3-chloropropyl)-4-(3-(trifluoromethyl)phenyl)-
CAS 78056-40-3C14H18ClF3N2
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-phenyl- chemical structure, C13H18N4O2, CAS 80712-07-8
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-phenyl-
CAS 80712-07-8C13H18N4O2
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(2-methylphenyl)- chemical structure, C14H20N4O2, CAS 80712-08-9
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(2-methylphenyl)-
CAS 80712-08-9C14H20N4O2
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(3-methylphenyl)- chemical structure, C14H20N4O2, CAS 80712-09-0
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(3-methylphenyl)-
CAS 80712-09-0C14H20N4O2
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(4-methylphenyl)- chemical structure, C14H20N4O2, CAS 80712-10-3
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(4-methylphenyl)-
CAS 80712-10-3C14H20N4O2
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(3-(trifluoromethyl)phenyl)- chemical structure, C14H17F3N4O2, CAS 80712-11-4
1-Piperazinecarboxamide, N-((methylamino)carbonyl)-4-(3-(trifluoromethyl)phenyl)-
CAS 80712-11-4C14H17F3N4O2
1-Piperazinecarboxamide, N-methyl-N-((methylamino)carbonyl)-4-phenyl- chemical structure, C14H20N4O2, CAS 80712-12-5
1-Piperazinecarboxamide, N-methyl-N-((methylamino)carbonyl)-4-phenyl-
CAS 80712-12-5C14H20N4O2
1-Piperazinecarboxamide, 4-(2-chlorophenyl)-N-methyl-N-((methylamino)carbonyl)- chemical structure, C14H19ClN4O2, CAS 80712-13-6
1-Piperazinecarboxamide, 4-(2-chlorophenyl)-N-methyl-N-((methylamino)carbonyl)-
CAS 80712-13-6C14H19ClN4O2
1-Piperazinecarboxamide, 4-(3-chlorophenyl)-N-methyl-N-((methylamino)carbonyl)- chemical structure, C14H19ClN4O2, CAS 80712-14-7
1-Piperazinecarboxamide, 4-(3-chlorophenyl)-N-methyl-N-((methylamino)carbonyl)-
CAS 80712-14-7C14H19ClN4O2
1-Piperazinecarboxamide, 4-(4-chlorophenyl)-N-methyl-N-((methylamino)carbonyl)- chemical structure, C14H19ClN4O2, CAS 80712-15-8
1-Piperazinecarboxamide, 4-(4-chlorophenyl)-N-methyl-N-((methylamino)carbonyl)-
CAS 80712-15-8C14H19ClN4O2
1-Piperazinecarboxamide, N-methyl-N-((methylamino)carbonyl)-4-(4-methylphenyl)- chemical structure, C15H22N4O2, CAS 80712-16-9
1-Piperazinecarboxamide, N-methyl-N-((methylamino)carbonyl)-4-(4-methylphenyl)-
CAS 80712-16-9C15H22N4O2
1-Piperazinecarboxamide, 4-(4-methoxyphenyl)-N-methyl-N-((methylamino)carbonyl)- chemical structure, C15H22N4O3, CAS 80712-17-0
1-Piperazinecarboxamide, 4-(4-methoxyphenyl)-N-methyl-N-((methylamino)carbonyl)-
CAS 80712-17-0C15H22N4O3
1-Piperazinecarboxamide, N-methyl-N-((methylamino)carbonyl)-4-(3-(trifluoromethyl)phenyl)- chemical structure, C15H19F3N4O2, CAS 80712-18-1
1-Piperazinecarboxamide, N-methyl-N-((methylamino)carbonyl)-4-(3-(trifluoromethyl)phenyl)-
CAS 80712-18-1C15H19F3N4O2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-phenyl-, monohydrochloride chemical structure, C15H23ClN4O2, CAS 80712-20-5
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-phenyl-, monohydrochloride
CAS 80712-20-5C15H23ClN4O2
1-Piperazinecarboxamide, 4-(2-chlorophenyl)-N-((dimethylamino)carbonyl)-N-methyl- chemical structure, C15H21ClN4O2, CAS 80712-21-6
1-Piperazinecarboxamide, 4-(2-chlorophenyl)-N-((dimethylamino)carbonyl)-N-methyl-
CAS 80712-21-6C15H21ClN4O2
1-Piperazinecarboxamide, 4-(3-chlorophenyl)-N-((dimethylamino)carbonyl)-N-methyl- chemical structure, C15H21ClN4O2, CAS 80712-22-7
1-Piperazinecarboxamide, 4-(3-chlorophenyl)-N-((dimethylamino)carbonyl)-N-methyl-
CAS 80712-22-7C15H21ClN4O2
1-Piperazinecarboxamide, 4-(4-chlorophenyl)-N-((dimethylamino)carbonyl)-N-methyl- chemical structure, C15H21ClN4O2, CAS 80712-23-8
1-Piperazinecarboxamide, 4-(4-chlorophenyl)-N-((dimethylamino)carbonyl)-N-methyl-
CAS 80712-23-8C15H21ClN4O2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-4-(3-fluorophenyl)-N-methyl- chemical structure, C15H21FN4O2, CAS 80712-24-9
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-4-(3-fluorophenyl)-N-methyl-
CAS 80712-24-9C15H21FN4O2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-4-(4-fluorophenyl)-N-methyl- chemical structure, C15H21FN4O2, CAS 80712-25-0
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-4-(4-fluorophenyl)-N-methyl-
CAS 80712-25-0C15H21FN4O2
1-Piperazinecarboxamide, 4-(4-bromophenyl)-N-((dimethylamino)carbonyl)-N-methyl- chemical structure, C15H21BrN4O2, CAS 80712-26-1
1-Piperazinecarboxamide, 4-(4-bromophenyl)-N-((dimethylamino)carbonyl)-N-methyl-
CAS 80712-26-1C15H21BrN4O2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-(4-methylphenyl)- chemical structure, C16H24N4O2, CAS 80712-27-2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-(4-methylphenyl)-
CAS 80712-27-2C16H24N4O2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-(3-(trifluoromethyl)phenyl)- chemical structure, C16H21F3N4O2, CAS 80712-28-3
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-(3-(trifluoromethyl)phenyl)-
CAS 80712-28-3C16H21F3N4O2
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-(4-(trifluoromethyl)phenyl)- chemical structure, C16H21F3N4O2, CAS 80712-29-4
1-Piperazinecarboxamide, N-((dimethylamino)carbonyl)-N-methyl-4-(4-(trifluoromethyl)phenyl)-
CAS 80712-29-4C16H21F3N4O2