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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings: 1
Scaffold atoms: 5
Chemicals: 1,868
With full pages: 279

Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold Open the Isothiazole page

Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,009 to 1,056 of 1,868 chemicals

Methyl 5-formyl-3-methoxy-1,2-thiazole-4-carboxylate chemical structure, C7H7NO4S, CAS 2095409-99-5

Methyl 5-formyl-3-methoxy-1,2-thiazole-4-carboxylate

CAS 2095409-99-5C₇H₇NO₄S

2-(1,2-Thiazol-5-yl)ethan-1-amine dihydrochloride chemical structure, C5H10Cl2N2S, CAS 2095409-66-6

2-(1,2-Thiazol-5-yl)ethan-1-amine dihydrochloride

CAS 2095409-66-6C₅H₁₀Cl₂N₂S

3-(Bromomethyl)-5-(trifluoromethyl)-1,2-thiazole chemical structure, C5H3BrF3NS, CAS 2253638-60-5

3-(Bromomethyl)-5-(trifluoromethyl)-1,2-thiazole

CAS 2253638-60-5C₅H₃BrF₃NS

4-Bromo-5-(difluoromethyl)-1,2-thiazole chemical structure, C4H2BrF2NS, CAS 2248384-04-3

4-Bromo-5-(difluoromethyl)-1,2-thiazole

CAS 2248384-04-3C₄H₂BrF₂NS

3-(Difluoromethyl)-1,2-thiazole-4-carboxylic acid chemical structure, C5H3F2NO2S, CAS 2248354-63-2

3-(Difluoromethyl)-1,2-thiazole-4-carboxylic acid

CAS 2248354-63-2C₅H₃F₂NO₂S

4-(Difluoromethyl)-3-methyl-1,2-thiazole-5-carboxylic acid chemical structure, C6H5F2NO2S, CAS 2248343-42-0

4-(Difluoromethyl)-3-methyl-1,2-thiazole-5-carboxylic acid

CAS 2248343-42-0C₆H₅F₂NO₂S

4-Bromo-5-(difluoromethyl)-3-methoxy-1,2-thiazole chemical structure, C5H4BrF2NOS, CAS 2248396-65-6

4-Bromo-5-(difluoromethyl)-3-methoxy-1,2-thiazole

CAS 2248396-65-6C₅H₄BrF₂NOS

tert-Butyl 4-amino-3-methyl-1,2-thiazole-5-carboxylate chemical structure, C9H14N2O2S, CAS 2248414-92-6

tert-Butyl 4-amino-3-methyl-1,2-thiazole-5-carboxylate

CAS 2248414-92-6C₉H₁₄N₂O₂S

5-(Difluoromethyl)-3-methoxy-1,2-thiazole-4-carboxylic acid chemical structure, C6H5F2NO3S, CAS 2248298-89-5

5-(Difluoromethyl)-3-methoxy-1,2-thiazole-4-carboxylic acid

CAS 2248298-89-5C₆H₅F₂NO₃S

Ethyl 4-amino-3-methyl-1,2-thiazole-5-carboxylate chemical structure, C7H10N2O2S, CAS 2248348-54-9

Ethyl 4-amino-3-methyl-1,2-thiazole-5-carboxylate

CAS 2248348-54-9C₇H₁₀N₂O₂S

5-Bromo-3-methyl-1,2-thiazole-4-carbaldehyde chemical structure, C5H4BrNOS, CAS 2248373-87-5

5-Bromo-3-methyl-1,2-thiazole-4-carbaldehyde

CAS 2248373-87-5C₅H₄BrNOS

4-Bromo-3-(difluoromethyl)-1,2-thiazole chemical structure, C4H2BrF2NS, CAS 2248400-73-7

4-Bromo-3-(difluoromethyl)-1,2-thiazole

CAS 2248400-73-7C₄H₂BrF₂NS

3-Bromo-4-(difluoromethyl)-1,2-thiazole chemical structure, C4H2BrF2NS, CAS 2248290-40-4

3-Bromo-4-(difluoromethyl)-1,2-thiazole

CAS 2248290-40-4C₄H₂BrF₂NS

5-Bromo-4-(difluoromethyl)-3-methyl-1,2-thiazole chemical structure, C5H4BrF2NS, CAS 2248400-97-5

5-Bromo-4-(difluoromethyl)-3-methyl-1,2-thiazole

CAS 2248400-97-5C₅H₄BrF₂NS

5-(Difluoromethyl)-1,2-thiazole-4-carboxylic acid chemical structure, C5H3F2NO2S, CAS 2248412-71-5

5-(Difluoromethyl)-1,2-thiazole-4-carboxylic acid

CAS 2248412-71-5C₅H₃F₂NO₂S

4-(Difluoromethyl)-1,2-thiazole-3-carboxylic acid chemical structure, C5H3F2NO2S, CAS 2248285-47-2

4-(Difluoromethyl)-1,2-thiazole-3-carboxylic acid

CAS 2248285-47-2C₅H₃F₂NO₂S

Methyl 5-formyl-1,2-thiazole-4-carboxylate chemical structure, C6H5NO3S, CAS 2248276-15-3

Methyl 5-formyl-1,2-thiazole-4-carboxylate

CAS 2248276-15-3C₆H₅NO₃S

Ethyl 2-amino-2-(1,2-thiazol-5-yl)acetate hydrochloride chemical structure, C7H11ClN2O2S, CAS 2287262-53-5

Ethyl 2-amino-2-(1,2-thiazol-5-yl)acetate hydrochloride

CAS 2287262-53-5C₇H₁₁ClN₂O₂S

Ethyl 2-amino-2-(1,2-thiazol-5-yl)acetate chemical structure, C7H10N2O2S, CAS 2026218-00-6

Ethyl 2-amino-2-(1,2-thiazol-5-yl)acetate

CAS 2026218-00-6C₇H₁₀N₂O₂S

1-(Dimethoxy-1,2-thiazol-4-yl)ethan-1-amine hydrochloride chemical structure, C7H13ClN2O2S, CAS 2287314-62-7

1-(Dimethoxy-1,2-thiazol-4-yl)ethan-1-amine hydrochloride

CAS 2287314-62-7C₇H₁₃ClN₂O₂S

1-(3,5-Dimethoxy-1,2-thiazol-4-yl)ethan-1-amine chemical structure, C7H12N2O2S, CAS 2281521-91-1

1-(3,5-Dimethoxy-1,2-thiazol-4-yl)ethan-1-amine

CAS 2281521-91-1C₇H₁₂N₂O₂S

1-(1,2-Thiazol-4-yl)ethan-1-amine dihydrochloride chemical structure, C5H10Cl2N2S, CAS 2287288-88-2

1-(1,2-Thiazol-4-yl)ethan-1-amine dihydrochloride

CAS 2287288-88-2C₅H₁₀Cl₂N₂S

2-{[(tert-Butoxy)carbonyl]amino}-2-(1,2-thiazol-5-yl)aceticacid chemical structure, C10H14N2O4S, CAS 1999072-08-0

2-{[(tert-Butoxy)carbonyl]amino}-2-(1,2-thiazol-5-yl)aceticacid

CAS 1999072-08-0C₁₀H₁₄N₂O₄S

Methyl 5-amino-3-tert-butyl-1,2-thiazole-4-carboxylate chemical structure, C9H14N2O2S, CAS 2138226-81-8

Methyl 5-amino-3-tert-butyl-1,2-thiazole-4-carboxylate

CAS 2138226-81-8C₉H₁₄N₂O₂S