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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,105 to 1,152 of 1,868 chemicals

(3-Methoxy-1,2-thiazol-4-yl)methanol chemical structure, C5H7NO2S, CAS 2156132-22-6
(3-Methoxy-1,2-thiazol-4-yl)methanol
CAS 2156132-22-6C5H7NO2S
5-Methyl-1,2-thiazol-4-amine hydrochloride chemical structure, C4H7ClN2S, CAS 2624121-64-6
5-Methyl-1,2-thiazol-4-amine hydrochloride
CAS 2624121-64-6C4H7ClN2S
4-Bromo-1,2-thiazole-5-carbonitrile chemical structure, C4HBrN2S, CAS 2285215-08-7
4-Bromo-1,2-thiazole-5-carbonitrile
CAS 2285215-08-7C4HBrN2S
1-(5-Bromo-1,2-thiazol-3-yl)methanamine hydrochloride chemical structure, C4H6BrClN2S, CAS 2493200-78-3
1-(5-Bromo-1,2-thiazol-3-yl)methanamine hydrochloride
CAS 2493200-78-3C4H6BrClN2S
4-Ethynyl-3,5-dimethyl-1,2-thiazole chemical structure, C7H7NS, CAS 2384541-72-2
4-Ethynyl-3,5-dimethyl-1,2-thiazole
CAS 2384541-72-2C7H7NS
5-Bromo-3-methylisothiazol-4-amine hydrochloride chemical structure, C4H6BrClN2S, CAS 2639413-85-5
5-Bromo-3-methylisothiazol-4-amine hydrochloride
CAS 2639413-85-5C4H6BrClN2S
5-Bromo-1,2-thiazol-4-amine hydrochloride chemical structure, C3H4BrClN2S, CAS 2639464-36-9
5-Bromo-1,2-thiazol-4-amine hydrochloride
CAS 2639464-36-9C3H4BrClN2S
Methyl[(3-methyl-1,2-thiazol-4-yl)methyl]amine dihydrochloride chemical structure, C6H12Cl2N2S, CAS 2648948-74-5
Methyl[(3-methyl-1,2-thiazol-4-yl)methyl]amine dihydrochloride
CAS 2648948-74-5C6H12Cl2N2S
2-Chloro-1-(5-methyl-1,2-thiazol-4-yl)ethan-1-one chemical structure, C6H6ClNOS, CAS 2648941-49-3
2-Chloro-1-(5-methyl-1,2-thiazol-4-yl)ethan-1-one
CAS 2648941-49-3C6H6ClNOS
4,4,4-Trifluoro-N-(3-methyl-1,2-thiazol-5-yl)butanamide chemical structure, C8H9F3N2OS, CAS 2329212-28-2
4,4,4-Trifluoro-N-(3-methyl-1,2-thiazol-5-yl)butanamide
CAS 2329212-28-2C8H9F3N2OS
(3-Methoxy-1,2-thiazol-5-yl)methanethiol chemical structure, C5H7NOS2, CAS 2172447-56-0
(3-Methoxy-1,2-thiazol-5-yl)methanethiol
CAS 2172447-56-0C5H7NOS2
3-Isothiazolemethanol, 3-methanesulfonate chemical structure, C5H7NO3S2, CAS 2274329-25-6
3-Isothiazolemethanol, 3-methanesulfonate
CAS 2274329-25-6C5H7NO3S2
(R)-1-(3-Chloroisothiazol-4-yl)ethan-1-ol chemical structure, C5H6ClNOS, CAS 2643340-79-6
(R)-1-(3-Chloroisothiazol-4-yl)ethan-1-ol
CAS 2643340-79-6C5H6ClNOS
1-(3-Chloro-4-isothiazolyl)ethanone chemical structure, C5H4ClNOS, CAS 2643340-78-5
1-(3-Chloro-4-isothiazolyl)ethanone
CAS 2643340-78-5C5H4ClNOS
(R)-1-(5-Chloroisothiazol-4-yl)ethan-1-ol chemical structure, C5H6ClNOS, CAS 2643341-23-3
(R)-1-(5-Chloroisothiazol-4-yl)ethan-1-ol
CAS 2643341-23-3C5H6ClNOS
tert-Butyl N-[2-oxo-2-(1,2-thiazol-5-yl)ethyl]carbamate chemical structure, C10H14N2O3S, CAS 1999650-79-1
tert-Butyl N-[2-oxo-2-(1,2-thiazol-5-yl)ethyl]carbamate
CAS 1999650-79-1C10H14N2O3S
3-Methylisothiazole-5-sulfonic acid methylamide chemical structure, C5H8N2O2S2, CAS 2737207-63-3
3-Methylisothiazole-5-sulfonic acid methylamide
CAS 2737207-63-3C5H8N2O2S2
Isothiazol-4-ylmethyl-methyl-amine HCl chemical structure, C5H9ClN2S, CAS 2682114-42-5
Isothiazol-4-ylmethyl-methyl-amine HCl
CAS 2682114-42-5C5H9ClN2S
4-Bromo-5-ethyl-isothiazole chemical structure, C5H6BrNS, CAS 2792724-46-8
4-Bromo-5-ethyl-isothiazole
CAS 2792724-46-8C5H6BrNS
5-(Prop-1-en-2-yl)isothiazole chemical structure, C6H7NS, CAS 2294904-07-5
5-(Prop-1-en-2-yl)isothiazole
CAS 2294904-07-5C6H7NS
Ethyl 3-ethyl-5-isothiazolecarboxylate chemical structure, C8H11NO2S, CAS 2106228-98-0
Ethyl 3-ethyl-5-isothiazolecarboxylate
CAS 2106228-98-0C8H11NO2S
3-Methyl-4-(1,2-thiazol-5-yl)butan-2-ol chemical structure, C8H13NOS, CAS 2027708-23-0
3-Methyl-4-(1,2-thiazol-5-yl)butan-2-ol
CAS 2027708-23-0C8H13NOS
(5-Ethylisothiazol-3-yl)methanol chemical structure, C6H9NOS, CAS 2739830-39-6
(5-Ethylisothiazol-3-yl)methanol
CAS 2739830-39-6C6H9NOS
tert-Butyl (4-iodoisothiazol-5-yl)carbamate chemical structure, C8H11IN2O2S, CAS 2227013-83-2
tert-Butyl (4-iodoisothiazol-5-yl)carbamate
CAS 2227013-83-2C8H11IN2O2S