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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
5
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,057 to 1,104 of 1,868 chemicals

5-Bromo-4-(bromomethyl)-1,2-thiazole chemical structure, C4H3Br2NS, CAS 2375260-27-6
5-Bromo-4-(bromomethyl)-1,2-thiazole
CAS 2375260-27-6C4H3Br2NS
Methyl 4-formyl-1,2-thiazole-5-carboxylate chemical structure, C6H5NO3S, CAS 2375270-36-1
Methyl 4-formyl-1,2-thiazole-5-carboxylate
CAS 2375270-36-1C6H5NO3S
4-Methyl-1,2-thiazol-5-amine hydrochloride chemical structure, C4H7ClN2S, CAS 605663-20-5
4-Methyl-1,2-thiazol-5-amine hydrochloride
CAS 605663-20-5C4H7ClN2S
5-Iodo-1,2-thiazole-3-carboxylic acid chemical structure, C4H2INO2S, CAS 2167956-38-7
5-Iodo-1,2-thiazole-3-carboxylic acid
CAS 2167956-38-7C4H2INO2S
[5-(Trifluoromethyl)-1,2-thiazol-3-yl]methanamine chemical structure, C5H5F3N2S, CAS 2375268-21-4
[5-(Trifluoromethyl)-1,2-thiazol-3-yl]methanamine
CAS 2375268-21-4C5H5F3N2S
2-Chloro-N-[1-(1,2-thiazol-5-yl)ethyl]propanamide chemical structure, C8H11ClN2OS, CAS 2168946-83-4
2-Chloro-N-[1-(1,2-thiazol-5-yl)ethyl]propanamide
CAS 2168946-83-4C8H11ClN2OS
4-(2-Bromoethynyl)-3-methyl-1,2-thiazole chemical structure, C6H4BrNS, CAS 2402829-71-2
4-(2-Bromoethynyl)-3-methyl-1,2-thiazole
CAS 2402829-71-2C6H4BrNS
4-Ethynyl-3-methyl-1,2-thiazole chemical structure, C6H5NS, CAS 2402839-35-2
4-Ethynyl-3-methyl-1,2-thiazole
CAS 2402839-35-2C6H5NS
Sodium 1,2-thiazole-5-sulfinate chemical structure, C3H2NNaO2S2, CAS 2137915-98-9
Sodium 1,2-thiazole-5-sulfinate
CAS 2137915-98-9C3H2NNaO2S2
(5-Nitroisothiazol-3-yl)methanol chemical structure, C4H4N2O3S, CAS 2271348-91-3
(5-Nitroisothiazol-3-yl)methanol
CAS 2271348-91-3C4H4N2O3S
3-(Difluoromethyl)isothiazol-5-amine chemical structure, C4H4F2N2S, CAS 2270872-91-6
3-(Difluoromethyl)isothiazol-5-amine
CAS 2270872-91-6C4H4F2N2S
4-Bromo-1,2-thiazole-3-carbonitrile chemical structure, C4HBrN2S, CAS 89089-06-5
4-Bromo-1,2-thiazole-3-carbonitrile
CAS 89089-06-5C4HBrN2S
(E)-N-[(3,5-Dimethoxy-1,2-thiazol-4-yl)methyl]-4-(dimethylamino)but-2-enamide chemical structure, C12H19N3O3S, CAS 2411337-55-6
(E)-N-[(3,5-Dimethoxy-1,2-thiazol-4-yl)methyl]-4-(dimethylamino)but-2-enamide
CAS 2411337-55-6C12H19N3O3S
(E)-4-(Dimethylamino)-N-[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]but-2-enamide chemical structure, C12H19N3O2S, CAS 2411331-52-5
(E)-4-(Dimethylamino)-N-[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]but-2-enamide
CAS 2411331-52-5C12H19N3O2S
N-[(3,5-Dimethoxy-1,2-thiazol-4-yl)methyl]but-2-ynamide chemical structure, C10H12N2O3S, CAS 2411312-96-2
N-[(3,5-Dimethoxy-1,2-thiazol-4-yl)methyl]but-2-ynamide
CAS 2411312-96-2C10H12N2O3S
2-Chloro-N-[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]acetamide chemical structure, C8H11ClN2O2S, CAS 2294753-44-7
2-Chloro-N-[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]acetamide
CAS 2294753-44-7C8H11ClN2O2S
3-(Difluoromethyl)-5-nitroisothiazole chemical structure, C4H2F2N2O2S, CAS 2270876-63-4
3-(Difluoromethyl)-5-nitroisothiazole
CAS 2270876-63-4C4H2F2N2O2S
3-tert-Butyl-1,2-thiazol-4-amine chemical structure, C7H12N2S, CAS 82560-17-6
3-tert-Butyl-1,2-thiazol-4-amine
CAS 82560-17-6C7H12N2S
(1,2-Thiazol-4-yl)methanethiol chemical structure, C4H5NS2, CAS 2171918-48-0
(1,2-Thiazol-4-yl)methanethiol
CAS 2171918-48-0C4H5NS2
3-Ethyl-1,2-thiazol-4-amine chemical structure, C5H8N2S, CAS 2743438-87-9
3-Ethyl-1,2-thiazol-4-amine
CAS 2743438-87-9C5H8N2S
Ethyl 4-methyl-5-isothiazolecarboxylate chemical structure, C7H9NO2S, CAS 15901-62-9
Ethyl 4-methyl-5-isothiazolecarboxylate
CAS 15901-62-9C7H9NO2S
Methyl 3-(bromomethyl)-1,2-thiazole-4-carboxylate chemical structure, C6H6BrNO2S, CAS 15901-71-0
Methyl 3-(bromomethyl)-1,2-thiazole-4-carboxylate
CAS 15901-71-0C6H6BrNO2S
tert-Butyl ((4-bromoisothiazol-3-yl)methyl)carbamate chemical structure, C9H13BrN2O2S, CAS 2375192-78-0
tert-Butyl ((4-bromoisothiazol-3-yl)methyl)carbamate
CAS 2375192-78-0C9H13BrN2O2S
(S)-1-(4-Bromoisothiazol-3-yl)ethan-1-amine chemical structure, C5H7BrN2S, CAS 2411592-37-3
(S)-1-(4-Bromoisothiazol-3-yl)ethan-1-amine
CAS 2411592-37-3C5H7BrN2S