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Murcko scaffold

6-Phenyl-2-pyridone scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
360
With full pages
43
Scaffold SMILES

O=c1cccc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-2-pyridone page
Murcko scaffold O=c1cccc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 360 chemicals

Diethyl 2-hydroxy-5-nitro-6-phenylpyridine-3,4-dicarboxylate chemical structure, C17H16N2O7, CAS 143323-42-6
Diethyl 2-hydroxy-5-nitro-6-phenylpyridine-3,4-dicarboxylate
CAS 143323-42-6C17H16N2O7
3,4-Diethoxycarbonyl-6-phenyl-2-pyridone chemical structure, C17H17NO5, CAS 39632-84-3
3,4-Diethoxycarbonyl-6-phenyl-2-pyridone
CAS 39632-84-3C17H17NO5
6-(3-Nitrophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C12H7N3O3, CAS 56916-10-0
6-(3-Nitrophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 56916-10-0C12H7N3O3
6-[4-(Dimethylamino)phenyl]-2-oxo-1H-pyridine-3-carboxylic acid chemical structure, C14H14N2O3, CAS 1282753-08-5
6-[4-(Dimethylamino)phenyl]-2-oxo-1H-pyridine-3-carboxylic acid
CAS 1282753-08-5C14H14N2O3
6-(3-Aminophenyl)pyridin-2-ol chemical structure, C11H10N2O, CAS 161887-04-3
6-(3-Aminophenyl)pyridin-2-ol
CAS 161887-04-3C11H10N2O
6-(4-Chlorophenyl)-2-hydroxypyridine chemical structure, C11H8ClNO, CAS 154476-86-5
6-(4-Chlorophenyl)-2-hydroxypyridine
CAS 154476-86-5C11H8ClNO
Methyl 3-(5-amino-1,6-dihydro-6-oxo-2-pyridinyl)benzoate chemical structure, C13H12N2O3, CAS 147284-88-6
Methyl 3-(5-amino-1,6-dihydro-6-oxo-2-pyridinyl)benzoate
CAS 147284-88-6C13H12N2O3
3-Amino-6-phenylpyridin-2(1H)-one chemical structure, C11H10N2O, CAS 203578-26-1
3-Amino-6-phenylpyridin-2(1H)-one
CAS 203578-26-1C11H10N2O
2-Butenedioic acid, 2-(2-oxo-6-phenyl-1(2H)-pyridinyl)-, diethyl ester, (E)- chemical structure, C19H19NO5, CAS 54802-15-2
2-Butenedioic acid, 2-(2-oxo-6-phenyl-1(2H)-pyridinyl)-, diethyl ester, (E)-
CAS 54802-15-2C19H19NO5
2-Hydroxy-6-(3-methoxyphenyl)nicotinic acid chemical structure, C13H11NO4, CAS 947013-49-2
2-Hydroxy-6-(3-methoxyphenyl)nicotinic acid
CAS 947013-49-2C13H11NO4
6-(3-Bromophenyl)-2-oxo-1H-pyridine-3-carbonitrile chemical structure, C12H7BrN2O, CAS 142499-50-1
6-(3-Bromophenyl)-2-oxo-1H-pyridine-3-carbonitrile
CAS 142499-50-1C12H7BrN2O
6-(4-Bromophenyl)-2-oxo-1H-pyridine-3-carbonitrile chemical structure, C12H7BrN2O, CAS 149557-07-3
6-(4-Bromophenyl)-2-oxo-1H-pyridine-3-carbonitrile
CAS 149557-07-3C12H7BrN2O
6-(3-Methylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C13H11NO3, CAS 1049130-41-7
6-(3-Methylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1049130-41-7C13H11NO3
2-Hydroxy-6-(4-methylsulfonylphenyl)pyridine chemical structure, C12H11NO3S, CAS 1125440-14-3
2-Hydroxy-6-(4-methylsulfonylphenyl)pyridine
CAS 1125440-14-3C12H11NO3S
Ethyl 2-hydroxy-6-phenylnicotinate chemical structure, C14H13NO3, CAS 58787-26-1
Ethyl 2-hydroxy-6-phenylnicotinate
CAS 58787-26-1C14H13NO3
2(1H)-Pyridinone, 3-(aminomethyl)-4-methyl-6-phenyl- chemical structure, C13H14N2O, CAS 771573-87-6
2(1H)-Pyridinone, 3-(aminomethyl)-4-methyl-6-phenyl-
CAS 771573-87-6C13H14N2O
2(1H)-Pyridinone, 5-acetyl-3-methyl-6-phenyl- chemical structure, C14H13NO2, CAS 798555-49-4
2(1H)-Pyridinone, 5-acetyl-3-methyl-6-phenyl-
CAS 798555-49-4C14H13NO2
6-(2-Methylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C13H10N2O, CAS 1204297-65-3
6-(2-Methylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1204297-65-3C13H10N2O
6-(2-Methylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C13H11NO3, CAS 1204296-40-1
6-(2-Methylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1204296-40-1C13H11NO3
6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C12H6F2N2O, CAS 1204296-69-4
6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1204296-69-4C12H6F2N2O
6-(2-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C12H7FN2O, CAS 1204297-30-2
6-(2-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1204297-30-2C12H7FN2O
6-(3-Bromophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C12H8BrNO3, CAS 1204296-95-6
6-(3-Bromophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1204296-95-6C12H8BrNO3
6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C12H7F2NO3, CAS 1204296-90-1
6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1204296-90-1C12H7F2NO3
6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C12H8FNO3, CAS 31695-73-5
6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 31695-73-5C12H8FNO3