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Murcko scaffold

6-Phenyl-2-pyridone scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
360
With full pages
43
Scaffold SMILES

O=c1cccc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-2-pyridone page
Murcko scaffold O=c1cccc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 360 chemicals

6-(4-Cyanophenyl)-2-hydroxypyridine chemical structure, C12H8N2O, CAS 1111110-50-9
6-(4-Cyanophenyl)-2-hydroxypyridine
CAS 1111110-50-9C12H8N2O
2-(6-Oxo-1,6-dihydropyridin-2-yl)benzaldehyde chemical structure, C12H9NO2, CAS 1111114-36-3
2-(6-Oxo-1,6-dihydropyridin-2-yl)benzaldehyde
CAS 1111114-36-3C12H9NO2
6-(3-Formylphenyl)-2-hydroxypyridine chemical structure, C12H9NO2, CAS 1111105-36-2
6-(3-Formylphenyl)-2-hydroxypyridine
CAS 1111105-36-2C12H9NO2
4-(6-Hydroxypyridin-2-yl)benzaldehyde chemical structure, C12H9NO2, CAS 1111105-38-4
4-(6-Hydroxypyridin-2-yl)benzaldehyde
CAS 1111105-38-4C12H9NO2
6-(2,3-Dimethylphenyl)pyridin-2(1H)-one chemical structure, C13H13NO, CAS 1111111-17-1
6-(2,3-Dimethylphenyl)pyridin-2(1H)-one
CAS 1111111-17-1C13H13NO
6-(2,5-Dimethylphenyl)-2-hydroxypyridine chemical structure, C13H13NO, CAS 1111105-24-8
6-(2,5-Dimethylphenyl)-2-hydroxypyridine
CAS 1111105-24-8C13H13NO
6-(2,4-Dimethylphenyl)pyridin-2(1H)-one chemical structure, C13H13NO, CAS 180606-06-8
6-(2,4-Dimethylphenyl)pyridin-2(1H)-one
CAS 180606-06-8C13H13NO
6-(3,5-Dimethylphenyl)-2-hydroxypyridine chemical structure, C13H13NO, CAS 1111110-98-5
6-(3,5-Dimethylphenyl)-2-hydroxypyridine
CAS 1111110-98-5C13H13NO
2-Hydroxy-6-(2-hydroxymethylphenyl)pyridine chemical structure, C12H11NO2, CAS 1111105-34-0
2-Hydroxy-6-(2-hydroxymethylphenyl)pyridine
CAS 1111105-34-0C12H11NO2
2-Hydroxy-6-(3-hydroxymethylphenyl)pyridine chemical structure, C12H11NO2, CAS 1111105-35-1
2-Hydroxy-6-(3-hydroxymethylphenyl)pyridine
CAS 1111105-35-1C12H11NO2
2-Hydroxy-6-(4-hydroxymethylphenyl)pyridine chemical structure, C12H11NO2, CAS 1111114-64-7
2-Hydroxy-6-(4-hydroxymethylphenyl)pyridine
CAS 1111114-64-7C12H11NO2
6-(2-Fluoro-4-methylphenyl)-2-hydroxypyridine chemical structure, C12H10FNO, CAS 1111110-97-4
6-(2-Fluoro-4-methylphenyl)-2-hydroxypyridine
CAS 1111110-97-4C12H10FNO
6-(2-Fluoro-5-methylphenyl)-2-hydroxypyridine chemical structure, C12H10FNO, CAS 1111113-00-8
6-(2-Fluoro-5-methylphenyl)-2-hydroxypyridine
CAS 1111113-00-8C12H10FNO
6-(3-Fluoro-2-methylphenyl)-2-hydroxypyridine chemical structure, C12H10FNO, CAS 1261931-50-3
6-(3-Fluoro-2-methylphenyl)-2-hydroxypyridine
CAS 1261931-50-3C12H10FNO
6-(3-Fluoro-4-methylphenyl)-2-hydroxypyridine chemical structure, C12H10FNO, CAS 1111113-03-1
6-(3-Fluoro-4-methylphenyl)-2-hydroxypyridine
CAS 1111113-03-1C12H10FNO
6-(4-Fluoro-3-methylphenyl)-2-hydroxypyridine chemical structure, C12H10FNO, CAS 1111110-66-7
6-(4-Fluoro-3-methylphenyl)-2-hydroxypyridine
CAS 1111110-66-7C12H10FNO
6-(5-Fluoro-2-methylphenyl)-2-hydroxypyridine chemical structure, C12H10FNO, CAS 1111112-99-2
6-(5-Fluoro-2-methylphenyl)-2-hydroxypyridine
CAS 1111112-99-2C12H10FNO
6-(3-Fluoro-4-hydroxyphenyl)pyridin-2(1H)-one chemical structure, C11H8FNO2, CAS 1111111-14-8
6-(3-Fluoro-4-hydroxyphenyl)pyridin-2(1H)-one
CAS 1111111-14-8C11H8FNO2
6-(3-Fluoro-5-hydroxyphenyl)pyridin-2(1H)-one chemical structure, C11H8FNO2, CAS 1261895-39-9
6-(3-Fluoro-5-hydroxyphenyl)pyridin-2(1H)-one
CAS 1261895-39-9C11H8FNO2
6-(4-Fluoro-2-hydroxyphenyl)pyridin-2(1H)-one chemical structure, C11H8FNO2, CAS 1261924-70-2
6-(4-Fluoro-2-hydroxyphenyl)pyridin-2(1H)-one
CAS 1261924-70-2C11H8FNO2
6-(5-Fluoro-2-hydroxyphenyl)pyridin-2(1H)-one chemical structure, C11H8FNO2, CAS 1111111-53-5
6-(5-Fluoro-2-hydroxyphenyl)pyridin-2(1H)-one
CAS 1111111-53-5C11H8FNO2
6-(2-Chlorophenyl)-2-hydroxypyridine chemical structure, C11H8ClNO, CAS 1111114-35-2
6-(2-Chlorophenyl)-2-hydroxypyridine
CAS 1111114-35-2C11H8ClNO
6-(2,4-Difluorophenyl)pyridin-2(1H)-one chemical structure, C11H7F2NO, CAS 1111110-73-6
6-(2,4-Difluorophenyl)pyridin-2(1H)-one
CAS 1111110-73-6C11H7F2NO
6-(2,3-Difluorophenyl)pyridin-2(1H)-one chemical structure, C11H7F2NO, CAS 1111110-46-3
6-(2,3-Difluorophenyl)pyridin-2(1H)-one
CAS 1111110-46-3C11H7F2NO